公开(公告)号：US06409721B1

公开(公告)日：2002-06-25

申请号：US09523540

申请日：2000-03-10

申请人： E. Thomas Wheelock ,  Erik T. Engelson ,  Harold F. Carrison

发明人： E. Thomas Wheelock ,  Erik T. Engelson ,  Harold F. Carrison

IPC分类号： A61B1814

CPC分类号： A61B17/12022 ,  A61B17/1214 ,  A61B2017/12063

摘要： This invention is an apparatus for the formation of occlusions in spaces in the human body, occluding such as thrombi in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas. In particular, it deals with a one piece assembly having an improved electrolytically erodable link to an occlusive member and further having an incorporated return electrode in the assembly. The occlusion-forming member is introduced to and is intended to remain at the desired occlusion site. The invention also relates to the joint itself. The invention further includes a method for introduction and electrolytic separation of the device.

摘要翻译： 本发明是一种用于在人体空间中形成闭塞的装置，阻塞动脉，静脉，动脉瘤，血管畸形和动静脉瘘等血栓。 特别地，它涉及具有改进的电解腐蚀性连接到闭塞构件的一体式组件，并且在组件中还具有并入的返回电极。 将闭塞形成构件引入并且旨在保留在期望的闭塞部位。 本发明还涉及接头本身。 本发明还包括用于引入和电解分离该装置的方法。

公开(公告)号：US6066158A

公开(公告)日：2000-05-23

申请号：US686304

申请日：1996-07-25

申请人： Erik T. Engelson ,  Gene Samson

发明人： Erik T. Engelson ,  Gene Samson

IPC分类号： A61B17/22 ,  A61F2/958 ,  A61M29/00 ,  A61M29/02

CPC分类号： A61B17/3207 ,  A61B17/221 ,  A61B17/320725 ,  A61B17/32075 ,  A61B2017/22034 ,  A61B2017/22061 ,  A61B2017/2212 ,  A61M2025/1095 ,  A61M25/10 ,  A61M29/02

摘要： This is a surgical device usually delivered through an intravascular catheter. It is designed to pierce and remove emboli often found in tortuous vasculature. The device includes several sections. The device has a core element. Placed around the distal end of the core wire is a collapsible but self expanding embolism collection assembly. That collector assembly is typically joined to the core wire at its distal end. The collector assembly may have a generally conical distal portion when expanded and may have a proximal section having varied purposes, e.g. for centering the collector assembly in the vascular lumen. The assembly further may have an actuator which permits the collector assembly to expand after deployment.

摘要翻译： 这是通常通过血管内导管递送的手术装置。 它旨在刺穿和去除经常在弯曲脉管系统中发现的栓子。 该设备包括几个部分。 该设备具有核心元件。 放置在芯线远端的是可折叠但自膨胀的栓塞收集组件。 该集电器组件通常在其远端处连接到芯线。 收集器组件可以在膨胀时具有大致锥形的远侧部分，并且可以具有不同目的的近端部分，例如， 用于将收集器组件对准在血管腔中。 组件还可以具有致动器，其允许收集器组件在展开之后膨胀。

公开(公告)号：US6030369A

公开(公告)日：2000-02-29

申请号：US887950

申请日：1997-07-03

申请人： Erik T. Engelson ,  Mark Carter

发明人： Erik T. Engelson ,  Mark Carter

IPC分类号： A61M25/00 ,  A61M25/16 ,  A61M5/00

CPC分类号： A61M25/0045 ,  A61M2025/0042 ,  A61M25/0009

摘要： This is a catheter having a shaft, the layers of which are coextruded in an intermittently changing pattern that produces particular mechanical and frictional properties in the structure. The outer layer of the catheter shaft is comprised of a material which has greater flexibility than the material which comprises the inner layer of the catheter shaft. The stiffer material which comprises the inner layer has frictional properties which facilitate guidewire passage and control. The invention includes the substituent shaft per se and a method of making the shaft.

摘要翻译： 这是具有轴的导管，其轴线以间歇变化的图案共挤出，在结构中产生特定的机械和摩擦特性。 导管轴的外层由与包括导管轴的内层的材料相比具有更大柔性的材料构成。 包含内层的更硬的材料具有促进导丝通过和控制的摩擦性能。 本发明包括取代轴本身以及制造轴的方法。

公开(公告)号：US5984929A

公开(公告)日：1999-11-16

申请号：US941458

申请日：1997-09-30

申请人： Mehran Bashiri ,  Michael P. Wallace ,  Pete Phong Pham ,  Cong Thach ,  Chad C. Roue ,  Erik T. Engelson

发明人： Mehran Bashiri ,  Michael P. Wallace ,  Pete Phong Pham ,  Cong Thach ,  Chad C. Roue ,  Erik T. Engelson

IPC分类号： A61B17/12 ,  A61F2/01 ,  A61F2/02 ,  A61F2/06 ,  A61F2/84 ,  A61B17/00

CPC分类号： A61F2/95 ,  A61B17/12022 ,  A61B17/12113 ,  A61B17/12145 ,  A61B17/1215 ,  A61B17/12154 ,  A61F2/01 ,  A61B2017/12063 ,  A61F2002/011 ,  A61F2002/016 ,  A61F2002/9505 ,  A61F2230/0006 ,  A61F2230/005 ,  A61F2230/0069 ,  A61F2230/0091

摘要： This is an implant for placement in the human body and an assembly for so placing that implant. Most desirably, it is an implant for use in the vasculature of the human body and is used to occlude some space in that vasculature as a portion of a treatment regimen. The implant itself is preferably a component of a deployment device using an electrolytically severable joint. The implant is electrically isolated from the electrolytically severable joint by a highly resistive or insulative layer. Such isolation and minimization of the conductive pathway from the placement apparatus to the body's fluids appears to enhance the susceptibility of the electrolytic joint to quick erosion and detachment of the implant from the deployment media. Although the implant itself is preferably a vaso-occlusive device, it may instead be a stent, a vena cava filter, or other implant which may be installed in this manner.

摘要翻译： 这是用于放置在人体中的植入物和用于使得植入物放置的组件。 最理想的是，它是用于人体脉管系统的植入物，并且用于封闭该脉管系统中的一些空间作为治疗方案的一部分。 植入物本身优选是使用电解可分割接头的展开装置的部件。 植入物通过高电阻或绝缘层与电解可分离的接头电隔离。 从放置装置到身体的流体的导电通路的这种隔离和最小化似乎增强了电解接头对植入物从展开介质的快速侵蚀和分离的敏感性。 虽然植入物本身优选为血管闭塞装置，但它可以是支架，腔静脉过滤器或可以以这种方式安装的其它植入物。

公开(公告)号：US5749849A

公开(公告)日：1998-05-12

申请号：US557075

申请日：1996-08-12

申请人： Erik T. Engelson

发明人： Erik T. Engelson

IPC分类号： A61M25/00 ,  A61M29/02 ,  A61M31/00

CPC分类号： A61M29/02 ,  A61M25/0045 ,  A61M25/0054 ,  A61M2025/0079 ,  A61M2025/1063

摘要： This invention is a single-lumen balloon catheter and assembly having a variable stiffness shaft that allows for greater guidewire trackability and proximal pushability than previous designs. The catheter has an elongate tubular body that is made of inner and outer coaxial tubes, the inner tube being made of proximal and distal sections, the proximal section being stiffer than the distal section and the distal section being stiffer than the outer tube.

摘要翻译： PCT No.PCT / US94 / 05679 Sec。 371日期：1996年8月12日 102（e）日期1996年8月12日PCT 1994年5月20日PCT公布。 公开号WO94 / 27668 日期1994年12月8日本发明是具有可变刚度轴的单腔气囊导管和组件，其允许比以前的设计更大的导丝跟踪性和近端推挤性。 导管具有由内外同轴管制成的细长管状体，内管由近端和远端部分制成，近端部分比远端部分更硬，远端部分比外管更硬。

公开(公告)号：US5261916A

公开(公告)日：1993-11-16

申请号：US806912

申请日：1991-12-12

申请人： Erik T. Engelson

发明人： Erik T. Engelson

IPC分类号： A61B17/03 ,  A61B17/12 ,  A61F2/88 ,  A61F2/95 ,  A61M25/12 ,  A61M25/14 ,  A61M29/00 ,  A61B17/00

CPC分类号： A61B17/12022 ,  A61B17/1214 ,  A61F2/88 ,  A61F2/95 ,  A61B2017/1205 ,  A61B2017/12054 ,  A61F2002/9505

摘要： A pusher-vasoocclusive coil assembly that is advanced through a catheter to a site within a vessel and is manipulated to detach the coil from the assembly. The coil has an enlarged member at its proximal end and the pusher has a keyway at its distal end that receives the enlarged member in interlocking engagement. The pusher and coil are coupled by placing the enlarged member in the keyway and enclosing the coupled assembly with a coaxial sleeve. The coil-pusher-sleeve assembly is positioned at the site and the sleeve is retracted to allow the member to move out of the keyway to uncouple the pusher and coil.

摘要翻译： 推进器 - 血管收缩线圈组件，其通过导管前进到血管内的部位，并被操纵以将线圈从组件分离。 线圈在其近端具有扩大的构件，并且推动器在其远端具有键槽，其接合互锁接合的扩大构件。 推动器和线圈通过将扩大构件放置在键槽中并且用同轴套筒封闭联接组件而联接。 线圈推动器 - 套筒组件定位在该位置处并且套筒缩回以允许构件移出键槽以使该推动器和线圈脱开。

公开(公告)号：US4739768A

公开(公告)日：1988-04-26

申请号：US869597

申请日：1986-06-02

申请人： Erik T. Engelson

发明人： Erik T. Engelson

IPC分类号： A61M25/01 ,  A61M25/00 ,  A61B6/00

CPC分类号： A61M25/09 ,  A61M25/0045 ,  A61M2025/0047 ,  A61M2025/0048

摘要： A catheter for use with a guide wire which can be guided from an external body access site to an internal tissue, and into the tissue along a tortuous path of at least about 5 cm through vessels of less than about 3 mm lumen inner diameter. The catheter includes a relatively stiff proximal segment dimensioned to track the wire from the access site to a region adjacent the internal tissue, and a relatively flexible distal segment dimensioned to track the wire along the tortuous path within the soft tissue.

摘要翻译： 一种用于导线的导管，其可以从外部身体进入部位被引导到内部组织，并且沿着至少约5cm的曲折路径通过小于约3mm管腔内径的血管进入组织。 导管包括相对刚性的近端段，其尺寸适于跟踪从进入位置到邻近内部组织的区域的线，以及尺寸适于沿着软组织内的曲折路径跟踪线的相对柔性的远侧段。

公开(公告)号：US4655746A

公开(公告)日：1987-04-07

申请号：US803816

申请日：1985-12-02

申请人： John R. Daniels ,  Erik T. Engelson ,  Garbriel B. Vegh

发明人： John R. Daniels ,  Erik T. Engelson ,  Garbriel B. Vegh

IPC分类号： A61F2/958 ,  A61M1/36 ,  A61M25/00

CPC分类号： A61M25/1011 ,  A61M1/3615

摘要： A catheter device for transferring fluid material to or from one or more selected-length segment of a vessel. The device includes first and second catheters, each having a tube with distal and proximal ends, an inflatable balloon carried on the tube, adjacent the distal tube end, and a fluid conduit for supplying the balloon, with such operatively positioned in the vessel. A central region of the second-catheter tube is axially shiftable within the first-catheter tube, allowing the balloons to be placed at desired relative positions in the vessel. Fluid is injected into the region between the two balloons through a fluid passageway formed in a channel in the first-catheter tube.

摘要翻译： 一种导管装置，用于将流体材料输送到或从容器的一个或多个选定长度的段进行传送。 该装置包括第一和第二导管，每个导管具有带有远端和近端的管，邻近远端管端承载在管上的可膨胀气囊，以及用于供应气囊的流体导管，可操作地定位在容器中。 第二导管管的中心区域在第一导管管内可轴向移动，允许气囊放置在容器中期望的相对位置。 流体通过形成在第一导管中的通道中的流体通道注入到两个气囊之间的区域中。

公开(公告)号：US5972019A

公开(公告)日：1999-10-26

申请号：US869346

申请日：1997-06-05

申请人： Erik T. Engelson ,  Gene Samson ,  Kim Nguyen ,  Rose Y. Wong

发明人： Erik T. Engelson ,  Gene Samson ,  Kim Nguyen ,  Rose Y. Wong

IPC分类号： A61B17/00 ,  A61B17/22 ,  A61F2/82 ,  A61M25/00 ,  A61M25/04 ,  A61M25/10 ,  A61M29/00 ,  A61M29/02

CPC分类号： A61B17/3207 ,  A61B17/221 ,  A61B17/320725 ,  A61B17/32075 ,  A61B2017/22034 ,  A61B2017/2212 ,  A61F2/013 ,  A61M2025/1095 ,  A61M25/10 ,  A61M29/02

摘要： This is a medical device. In particular, it is a surgical device usually delivered through an intravascular catheter. It may be used in several ways. It may, for instance, be used to open a clear passageway adjacent thrombus to allow both blood and medication to bypass the clot. It may be used to pierce and to remove thrombus. These thrombus are often found in tortuous vasculature. The device includes several sections. The device has a core element, typically a core wire. Placed around the distal end of the core element is a collapsible but preferably self expanding cage assembly. The cage assembly is preferably radio-opaque. The proximal end of the cage is typically is affixed to an actuator in such a way as to allow expansion of the cage after deployment. The cage assembly may have a generally conical distal or "trailing" portion when expanded and also a proximal section. The cage assembly may be used for collecting emboli or for displacing them to allow blood flow to resume. The proximal section may have various uses, e.g., for centering the collector assembly in the vascular lumen or for gathering larger amounts of the targeted clot or to act as a passageway for fluid flow. The assembly further may have an actuator which permits or causes the collector assembly to expand after deployment.

摘要翻译： 这是一种医疗器械。 特别地，它是通常通过血管内导管递送的手术装置。 它可以以几种方式使用。 例如，它可以用于打开邻近血栓的清晰通道，以允许血液和药物绕过凝块。 它可以用于刺穿和去除血栓。 这些血栓通常在曲折的脉管系统中发现。 该设备包括几个部分。 该装置具有核心元件，通常为芯线。 围绕芯元件的远端放置的是可折叠但优选自膨胀的笼组件。 笼组件优选地是不透射线的。 保持架的近端通常被固定到致动器上，以允许在展开之后使笼膨胀。 当膨胀时，笼组件可以具有大致锥形的远侧或“后退”部分，并且还具有近端部分。 笼组件可以用于收集栓塞或用于移位它们以允许血流恢复。 近端部分可以具有各种用途，例如用于将收集器组件对准在血管腔中或用于收集更大量的目标凝块或用作流体流动的通道。 组件还可具有致动器，该致动器允许或导致收集器组件在展开之后膨胀。

公开(公告)号：US5944733A

公开(公告)日：1999-08-31

申请号：US891936

申请日：1997-07-14

申请人： Erik T. Engelson

发明人： Erik T. Engelson

IPC分类号： A61B17/12

CPC分类号： A61B17/12145 ,  A61B17/12022 ,  A61B2017/12068

摘要： A vasoocclusive member, such as embolic coil, that mechanically joins an instrument for delivering that vasoocclusive member to a selected site within the vasculature or other lumen of a human body via the use of a catheter is provided. A thermoplastic member augments the junction to enhance variously the friction at an integrity of the junction. Once the vasoocclusive member is delivered to the desired site, radio frequency energy is supplied to the thermoplastic member in an amount sufficient to soften the thermoplastic member, allowing mechanical disengagement to then take place.

摘要翻译： 提供了一种血管闭塞性成员，例如栓塞线圈，其通过使用导管机械地连接用于将血管闭塞成员递送到人体的脉管系统或其他内腔内的选定部位的器械。 热塑性构件增加了接合部，以在连接处的完整性处不同地增强摩擦。 一旦血管充填构件被输送到期望的位置，则射频能量以足以软化热塑性构件的量被供应到热塑性构件，从而允许机械脱开。