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公开(公告)号：US20070066588A1
公开(公告)日：2007-03-22
申请号：US11518132
申请日：2006-09-08
申请人： Marlon Cowart , Minghua Sun , Chen Zhao , Guo Zheng
发明人： Marlon Cowart , Minghua Sun , Chen Zhao , Guo Zheng
IPC分类号： C07D417/02 , A61K31/55 , A61K31/5377 , A61K31/496 , A61K31/454 , A61K31/428
CPC分类号： C07D277/64 , C07D417/04 , C07D417/08 , C07D417/12 , C07D487/04
摘要： Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
摘要翻译： 式（I）化合物可用于治疗由组胺-3受体配体预防或改善的病症或病症。 还公开了包含组胺-3受体配体的药物组合物，使用这些化合物和组合物的方法，以及制备式（I）范围内的化合物的方法。
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公开(公告)号：US08592467B2
公开(公告)日：2013-11-26
申请号：US12489269
申请日：2009-06-22
申请人： Marlon D. Cowart , Minghua Sun , Chen Zhao , Guo Zhu Zheng
发明人： Marlon D. Cowart , Minghua Sun , Chen Zhao , Guo Zhu Zheng
IPC分类号： A61K31/428 , C07D277/62
CPC分类号： C07D277/64 , C07D417/04 , C07D417/08 , C07D417/12 , C07D487/04
摘要： Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
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![OCTAHYDRO-PYRROLO[3,4-B]PYRROLE DERIVATIVES](/abs-image/US/2010/09/02/US20100222358A1/abs.jpg.150x150.jpg)
公开(公告)号：US20100222358A1
公开(公告)日：2010-09-02
申请号：US12715660
申请日：2010-03-02
申请人： Marlon D. Cowart , Chen Zhao , Minghua Sun , Lawrence A. Black , Guo Zhu Zheng , Robert J. Gregg , Geoff G.Z. Zhang , Ahmad Y. Sheikh , Xiaochun Lou , Rodger F. Henry , David M. Barnes , Lawrence Kolaczkowski , Anthony R. Haight , Sou-Jen Chang , Steven J. Wittenberger , Michael G. Fickes
发明人： Marlon D. Cowart , Chen Zhao , Minghua Sun , Lawrence A. Black , Guo Zhu Zheng , Robert J. Gregg , Geoff G.Z. Zhang , Ahmad Y. Sheikh , Xiaochun Lou , Rodger F. Henry , David M. Barnes , Lawrence Kolaczkowski , Anthony R. Haight , Sou-Jen Chang , Steven J. Wittenberger , Michael G. Fickes
IPC分类号： A61K31/501 , A61K31/407 , C07D487/04 , A61K31/47 , C07D215/00 , A61K31/4439 , C07D401/14 , A61K31/428 , C07D417/14 , A61K31/4164 , C07D233/00 , C07D403/14 , A61K31/506 , A61K31/497 , A61P3/04 , A61P5/00 , A61P11/06 , A61P25/00 , A61P29/00 , A61P37/08 , A61P1/02
CPC分类号： C07D487/04
摘要： Octahydro-pyrrolo[3,4-b]pyrrole derivatives are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Octahydro-pyrrolo[3,4-b]pyrrole compounds, methods for using such compounds, compositions for making them, and processes for preparing such compounds are disclosed herein.
摘要翻译： 八氢吡咯并[3,4-b]吡咯衍生物可用于治疗组胺-3受体配体预防或改善的病症或病症。 八氢吡咯并[3,4-b]吡咯化合物，使用这些化合物的方法，制备它们的组合物和制备这些化合物的方法在本文中公开。
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公开(公告)号：US20080113982A1
公开(公告)日：2008-05-15
申请号：US12014566
申请日：2008-01-15
申请人： Chen Zhao , Minghua Sun , Marlon Cowart , Youssef Bennani
发明人： Chen Zhao , Minghua Sun , Marlon Cowart , Youssef Bennani
IPC分类号： A61K31/5377 , A61K31/403 , A61K31/427 , A61P3/08 , A61P25/28 , A61P9/00
CPC分类号： C07J71/00
摘要： Azacyclosteroid histamine-3 receptor ligands, pharmaceutical compositions comprising such compounds, and methods for using such compounds and compositions are described herein.
摘要翻译： 氮杂环绕组胺胺受体配体，包含这些化合物的药物组合物和使用这些化合物和组合物的方法在本文中描述。
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![Octahydro-pyrrolo[3,4-b]pyrrole Derivatives](/abs-image/US/2007/10/04/US20070232612A1/abs.jpg.150x150.jpg)
公开(公告)号：US20070232612A1
公开(公告)日：2007-10-04
申请号：US11674518
申请日：2007-02-13
申请人： Marlon Cowart , Chen Zhao , Minghua Sun , Lawrence Black , Guo Zheng , Robert Gregg , Geoff Zhang , Ahmand Sheikh , Xiaochun Lou , Rodger Henry , David Barnes , Lawrence Kolaczkowski , Anthony Haight , Sou-Jen Chang , Steven Wittenberger , Michael Fickes
发明人： Marlon Cowart , Chen Zhao , Minghua Sun , Lawrence Black , Guo Zheng , Robert Gregg , Geoff Zhang , Ahmand Sheikh , Xiaochun Lou , Rodger Henry , David Barnes , Lawrence Kolaczkowski , Anthony Haight , Sou-Jen Chang , Steven Wittenberger , Michael Fickes
IPC分类号： A61K31/506 , A61K31/501 , A61K31/496 , A61K31/4439 , A61K31/407 , C07D487/02 , A61K31/416
CPC分类号： C07D487/04
摘要： Octahydro-pyrrolo[3,4-b]pyrrole derivatives are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands, Octahydro-pyrrolo[3,4-b]pyrrole compounds, methods for using such compounds, compositions for making them, and processes for preparing such compounds are disclosed herein.
摘要翻译： 八氢 - 吡咯并[3,4-b]吡咯衍生物可用于治疗组胺-3受体配体，八氢吡咯并[3,4-b]吡咯化合物，使用这些化合物的方法，组合物 制备这些化合物的方法和方法。
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![Octahydro-pyrrolo[3,4-B]pyrrole derivatives](/abs-image/US/2013/03/19/US08399468B2/abs.jpg.150x150.jpg)
公开(公告)号：US08399468B2
公开(公告)日：2013-03-19
申请号：US12715660
申请日：2010-03-02
申请人： Marlon D. Cowart , Chen Zhao , Minghua Sun , Lawrence A. Black , Guo Zhu Zheng , Robert J. Gregg , Geoff G. Z. Zhang , Ahmad Y. Sheikh , Xiaochun Lou , Rodger F. Henry , David M. Barnes , Lawrence Kolaczkowski , Anthony R. Haight , Sou-Jen Chang , Steven J. Wittenberger , Michael G. Fickes
发明人： Marlon D. Cowart , Chen Zhao , Minghua Sun , Lawrence A. Black , Guo Zhu Zheng , Robert J. Gregg , Geoff G. Z. Zhang , Ahmad Y. Sheikh , Xiaochun Lou , Rodger F. Henry , David M. Barnes , Lawrence Kolaczkowski , Anthony R. Haight , Sou-Jen Chang , Steven J. Wittenberger , Michael G. Fickes
IPC分类号： A61K31/501 , C07D403/10
CPC分类号： C07D487/04
摘要： Octahydro-pyrrolo[3,4-b]pyrrole derivatives are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Octahydro-pyrrolo[3,4-b]pyrrole compounds, methods for using such compounds, compositions for making them, and processes for preparing such compounds are disclosed herein.
摘要翻译： 八氢吡咯并[3,4-b]吡咯衍生物可用于治疗组胺-3受体配体预防或改善的病症或病症。 八氢吡咯并[3,4-b]吡咯化合物，使用这些化合物的方法，制备它们的组合物和制备这些化合物的方法在本文中公开。
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公开(公告)号：US07576110B2
公开(公告)日：2009-08-18
申请号：US11518132
申请日：2006-09-08
申请人： Marlon D. Cowart , Minghua Sun , Chen Zhao , Guo Zhu Zheng
发明人： Marlon D. Cowart , Minghua Sun , Chen Zhao , Guo Zhu Zheng
IPC分类号： A61K31/428 , C07D277/62
CPC分类号： C07D277/64 , C07D417/04 , C07D417/08 , C07D417/12 , C07D487/04
摘要： Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
摘要翻译： 式（I）化合物可用于治疗由组胺-3受体配体预防或改善的病症或病症。 还公开了包含组胺-3受体配体的药物组合物，使用这些化合物和组合物的方法，以及制备式（I）范围内的化合物的方法。
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公开(公告)号：US20050227953A1
公开(公告)日：2005-10-13
申请号：US11096382
申请日：2005-04-01
申请人： Chen Zhao , Minghua Sun , Marlon Cowart , Youssef Bennani
发明人： Chen Zhao , Minghua Sun , Marlon Cowart , Youssef Bennani
CPC分类号： C07J71/00
摘要： Azacyclosteroid histamine-3 receptor ligands, pharmaceutical compositions comprising such compounds, and methods for using such compounds and compositions are described herein.
摘要翻译： 氮杂环绕组胺胺受体配体，包含这些化合物的药物组合物和使用这些化合物和组合物的方法在本文中描述。
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公开(公告)号：US20090326222A1
公开(公告)日：2009-12-31
申请号：US12489269
申请日：2009-06-22
申请人： Marlon D. Cowart , Minghua Sun , Chen Zhao , Guo Zhu Zheng
发明人： Marlon D. Cowart , Minghua Sun , Chen Zhao , Guo Zhu Zheng
IPC分类号： C07D413/14 , C07D417/14 , C07D401/14 , C07D277/62 , C07D237/02 , C07D213/02
CPC分类号： C07D277/64 , C07D417/04 , C07D417/08 , C07D417/12 , C07D487/04
摘要： Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
摘要翻译： 式（I）化合物可用于治疗由组胺-3受体配体预防或改善的病症或病症。 还公开了包含组胺-3受体配体的药物组合物，使用这些化合物和组合物的方法，以及制备式（I）范围内的化合物的方法。
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公开(公告)号：US07345034B2
公开(公告)日：2008-03-18
申请号：US11096382
申请日：2005-04-01
申请人： Chen Zhao , Minghua Sun , Marlon D. Cowart , Youssef L. Bennani
发明人： Chen Zhao , Minghua Sun , Marlon D. Cowart , Youssef L. Bennani
CPC分类号： C07J71/00
摘要： Azacyclosteroid histamine-3 receptor ligands, pharmaceutical compositions comprising such compounds, and methods for using such compounds and compositions are described herein.
摘要翻译： 氮杂环绕组胺胺受体配体，包含这些化合物的药物组合物和使用这些化合物和组合物的方法在本文中描述。
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