公开(公告)号：US20100094113A1

公开(公告)日：2010-04-15

申请号：US12576121

申请日：2009-10-08

申请人： Mark Ries Robinson ,  Mike Borrello ,  William R. Patterson

发明人： Mark Ries Robinson ,  Mike Borrello ,  William R. Patterson

IPC分类号： A61B5/1473 ,  A61B5/02 ,  A61B5/021

CPC分类号： A61B5/0215 ,  A61B5/14532 ,  A61B5/14546

摘要： The present invention provides methods and apparatuses that can provide measurement of analytes such as glucose with a variety of sensors in connection with hemodynamic monitoring. Some embodiments of the present invention enable the use of a single arterial access site for automated blood glucose measurement as well as hemodynamic monitoring. Some embodiments of the present invention can reduce or eliminate nuisance hemodynamic alarms. Some embodiments of the present invention can provide hemodynamic monitoring during an automated analyte measurement process. An example apparatus according to the present invention comprises a blood access system, adapted to remove blood from a body and infuse at least a portion of the blood back into the body. Such an apparatus also comprises an analyte sensor, mounted with or integrated into the blood access system such that the analyte sensor measures the analyte in the blood that has been removed from the body by the blood access system.

摘要翻译： 本发明提供了可以提供诸如葡萄糖等分析物与血液动力学监测相结合的各种传感器的测量方法和装置。 本发明的一些实施例使得能够使用单个动脉进入部位进行自动血糖测量以及血液动力学监测。 本发明的一些实施例可以减少或消除麻烦的血液动力学警报。 本发明的一些实施方案可以在自动分析物测量过程中提供血液动力学监测。 根据本发明的示例性装置包括血液存取系统，其适于从身体去除血液并将至少一部分血液注入体内。 这样的装置还包括安装有或集成到血液存取系统中的分析物传感器，使得分析物传感器测量血液中已被血液存取系统从体内除去的分析物。

公开(公告)号：US20090156975A1

公开(公告)日：2009-06-18

申请号：US12325243

申请日：2008-11-30

申请人： Mark Ries Robinson ,  Mike Borrello ,  Dan Welsh

发明人： Mark Ries Robinson ,  Mike Borrello ,  Dan Welsh

IPC分类号： A61M1/14 ,  B01D65/02

CPC分类号： A61M1/3653 ,  A61B5/0215 ,  A61B5/14532 ,  A61B5/15003 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150755 ,  A61B5/150946 ,  A61B5/150961 ,  A61B5/150992 ,  A61B5/153 ,  A61B5/155 ,  A61B5/157 ,  A61B5/4839 ,  A61M1/30 ,  A61M1/303 ,  A61M1/308 ,  A61M1/3656 ,  A61M1/3659 ,  A61M2005/1588 ,  A61M2039/0009

摘要： Embodiments of the present invention provide robust systems for the removal and subsequent infusion of blood for measurement purposes, and embodiments of the present invention provide methods of operating such systems and providing capabilities such as predicting and avoiding occlusions and/or bubbles, managing occlusions and/or bubbles if they occur, automatic cleaning of the blood access system, and determining and managing the patency of the blood access site. Such operational challenges can occur during any of several phases of operation of a blood access system. Embodiments of the present invention can effectively incorporate a variety of inputs for the identification of trends consistent with present or pending occlusions. An embodiment of the present invention can be aware of the stage of operation, e.g., withdrawal, infusion, or cleaning, and the prior performance of the system. Embodiments of the present invention can have the ability to identify the location of the problem so that effective procedures can be used to resolve the problem.

摘要翻译： 本发明的实施例提供用于去除和随后输注用于测量目的的血液的鲁棒系统，并且本发明的实施例提供了操作这样的系统并提供诸如预测和避免闭塞和/或气泡的能力的方法，管理闭塞和/ 如果发生气泡，自动清洗血液存取系统，以及确定和管理血液通道的通畅。 这样的操作挑战可以在血液存取系统的几个操作阶段的任何阶段发生。 本发明的实施例可以有效地结合用于识别与当前或未决遮挡一致的趋势的各种输入。 本发明的实施例可以意识到操作的阶段，例如撤回，输注或清洁，以及系统的先前的执行。 本发明的实施例可以具有识别问题的位置的能力，从而可以使用有效的过程来解决问题。