公开(公告)号：US20240358266A1

公开(公告)日：2024-10-31

申请号：US18643493

申请日：2024-04-23

Applicant: Neuro-Vascular Research and Design Corporation

Inventor： Jeffrey Owen ,  Nicholas Chung ,  H. Shields Day ,  Obed Espina

IPC: A61B5/026 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/391 ,  A61B5/395 ,  A61B5/397

CPC classification number: A61B5/0261 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/391 ,  A61B5/395 ,  A61B5/397 ,  A61B5/6813 ,  A61B5/6832 ,  A61B5/6838 ,  A61B5/7267 ,  A61B5/7405 ,  A61B5/742 ,  A61B5/746 ,  A61B2560/0204 ,  A61B2560/045 ,  A61B2560/0462 ,  A61B2562/0233 ,  A61B2562/227

Abstract: Exemplary embodiments provide an optical penile blood flow measuring technology for the monitoring of neurological and vascular function of structures at surgical risk. The measuring principle is to rely on optical absorption properties of blood components for penile blood flow monitoring. Certain embodiments use different wavelengths to measure changes in hemoglobin concentrations and are particularly advantageous in continuous, autonomous monitoring with real-time feedback to surgeons for potential intervention and decision-making in a timely manner. The measurements results can be used to provide real-time feedback to surgeons operating on the patient, or for off-line analysis and evaluation. Certain embodiments can operate autonomously in the continuous measurement mode, a synchronized mode, or a triggered mode, reducing the need of highly-skilled apparatus operators, allowing automatic and real-time warning to surgeons when operating in areas while preserving the functions of critical nerves, resulting in improved clinical outcomes and reducing operation costs.

公开(公告)号：US20240342503A1

公开(公告)日：2024-10-17

申请号：US18133927

申请日：2023-04-12

Applicant: Becton, Dickinson and Company

Inventor： Amanda Lingle ,  Megan Brooks ,  Morgan Izykowski ,  David Colton Jackson ,  Joseph Aamodt

IPC: A61N5/06 ,  A61B5/00 ,  A61B5/01 ,  A61B5/0538 ,  A61B5/145

CPC classification number: A61N5/0624 ,  A61B5/01 ,  A61B5/0538 ,  A61B5/14503 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/6852 ,  A61N5/0601 ,  A61N2005/063 ,  A61N2005/0651

Abstract: An indwelling medical device with stimuli-responsive antimicrobial properties. The medical device includes a polymeric substrate having one or more light-responsive antimicrobial compounds. The medical device includes a light source to provide light to the polymeric substrate and a sensor to detect infection or bacterial colonization. A controller is connected to the light source and to the sensor. The controller controls operation of the sensor and receives sensing signals from the sensor. The controller activates the light source in response to infection detection and release the antimicrobial compound. The light-responsive antimicrobial compound may include a nitric oxide donor, such as S-nitroso-n-acetylpenacillamine, S-nitrosoglutathione, or N-diazeniumdiolate (NONOate). The light-responsive antimicrobial compound may include a photocatalyst metal oxide, such as ZnO, CuO, or TiO2. The light-responsive antimicrobial compound may include a photosensitive dye, such as crystal violet, methylene blue ethyl violet, rose bengal, or malachite green.

公开(公告)号：US20240341643A1

公开(公告)日：2024-10-17

申请号：US18752091

申请日：2024-06-24

Applicant: Roche Diabetes Care, Inc.

Inventor： Helmut Walter

IPC: A61B5/1473 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1486 ,  B08B5/00 ,  B08B7/00

CPC classification number: A61B5/1473 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14865 ,  A61B5/6849 ,  B08B5/00 ,  B08B7/0035 ,  A61B5/688 ,  A61B2560/063 ,  A61B2562/166 ,  A61B2562/242

Abstract: Medical devices and methods are disclosed for detecting an analyte in a body fluid. The medical device comprises an analyte sensor having an insertable portion adapted for insertion into body tissue of a user. An insertion cannula receives the analyte sensor therein. A housing forms a sealed sensor compartment receiving an insertable portion of the analyte sensor. The sealed sensor compartment comprises a detachable upper cap and a detachable lower cap. The detachable lower cap is configured for detachment before sensor insertion. The cannula is attached to the detachable upper cap, wherein the detachable upper cap is configured for detachment after insertion, thereby removing the insertion cannula. The analyte sensor is operably connected to an electronics unit comprising an interconnect device with at least one electronic component attached thereto

公开(公告)号：US20240341639A1

公开(公告)日：2024-10-17

申请号：US18755915

申请日：2024-06-27

Applicant: ABBOTT DIABETES CARE INC.

Inventor： Benjamin Jay Feldman ,  Adam Heller ,  Namvar Kiaie

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/01 ,  A61B5/1486

CPC classification number: A61B5/14532 ,  A61B5/01 ,  A61B5/1451 ,  A61B5/14546 ,  A61B5/14865 ,  A61B5/746

Abstract: Embodiments of the present disclosure include a method for receiving sensor data indicative of a glucose level from a glucose sensor configured to be positioned in contact with a bodily fluid under a skin surface of a subject, receiving, from a temperature sensor, temperature data indicative of a temperature of the skin surface, determining a rate of change of the glucose level, wherein the rate of change indicates a presence of a hypoglycemic condition, determining that a variation of the temperature of the skin surface is within a predetermined range of temperature values, and determining, in response to the variation of the temperature data, that the rate of change of the glucose level corresponds to a sensor signal attenuation.

公开(公告)号：US20240341633A1

公开(公告)日：2024-10-17

申请号：US18642331

申请日：2024-04-22

Applicant: Senseonics, Incorporated

Inventor： Joon Chatterjee ,  Venkata Velvadapu ,  Mark Mortellaro ,  Philip Huffstetler

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1459 ,  A61B5/1473 ,  A61B5/1486 ,  A61L31/04 ,  A61L31/14 ,  A61L31/16 ,  C08F283/06 ,  C08K5/55 ,  G01N21/75 ,  G01N21/77 ,  G01N33/50

CPC classification number: A61B5/14503 ,  A61B5/14546 ,  A61L31/041 ,  A61L31/145 ,  A61L31/16 ,  C08F283/06 ,  C08K5/55 ,  G01N21/75 ,  G01N21/77 ,  G01N33/50 ,  A61B5/0031 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/1459 ,  A61B5/14735 ,  A61B5/14865

Abstract: A sensor (e.g., an optical sensor) that may be implanted within a living animal (e.g., a human) and may be used to measure an analyte (e.g., glucose or oxygen) in a medium (e.g., interstitial fluid, blood, or intraperitoneal fluid) within the animal. The sensor may include a sensor housing, an analyte indicator covering at least a portion of the sensor housing, and one or more compounds having metal chelating moieties that reduce degradation of the analyte indicator.

公开(公告)号：US20240341605A1

公开(公告)日：2024-10-17

申请号：US18636183

申请日：2024-04-15

Applicant: Stryker Corporation

Inventor： Frederick Allen MOORE ,  Lesley Myron OTSIG ,  Muhammad Nasir al-Din bin ZULKAFLY ,  Theodore Drew Fast HUSBY

IPC: A61B5/0205 ,  A61B1/00 ,  A61B1/04 ,  A61B5/00 ,  A61B5/02 ,  A61B5/145 ,  A61K49/00

CPC classification number: A61B5/0205 ,  A61B1/043 ,  A61B5/02007 ,  A61B5/14546 ,  A61K49/0017 ,  A61K49/0045 ,  A61B1/00 ,  A61B5/00 ,  A61B5/418

Abstract: Closed cavity adjustable sensor mount systems and methods are disclosed. The sensor mount systems include a sealed, closed cavity enclosing a sensor and forming a closed cavity sensor assembly. The closed cavity sensor assembly may be tilted and/or translated relative to a platform in order to adjust the orientation of the sensor to align it with an imaging optical axis. Following alignment, the closed cavity sensor assembly may be permanently or reversibly fixed in place. The closed cavity adjustable sensor mount systems may be part of medical imaging systems such as endoscopic imaging systems and/or open field imaging systems.

公开(公告)号：US12114975B2

公开(公告)日：2024-10-15

申请号：US16728652

申请日：2019-12-27

Applicant: DexCom, Inc.

Inventor： Sebastian Bohm ,  Anna Claire Harley-Trochimczyk ,  Daiting Rong ,  Rui Ma ,  Wenjie Lan ,  Minglian Shi ,  Disha B. Sheth

IPC: A61B5/1495 ,  A61B5/00 ,  A61B5/0537 ,  A61B5/145 ,  A61B5/1473 ,  A61B5/1486 ,  G01N27/02 ,  G01N27/22 ,  G01N27/24 ,  G01N33/487

CPC classification number: A61B5/1495 ,  A61B5/0537 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/14865 ,  A61B5/6844 ,  G01N27/221 ,  G01N27/24 ,  G01N33/48707 ,  A61B5/0004 ,  A61B5/0031 ,  A61B2560/0223 ,  A61B2560/0252 ,  A61B2560/0276 ,  G01N27/026

Abstract: Various examples are directed to systems and methods for operating an analyte sensor system using sensor electronics. An example method may comprise applying a bias voltage change to an analyte sensor bias voltage and measuring a current value for each of a plurality of time periods after application of the bias voltage change. The example method may also comprise determining an estimated impedance using the current values for the plurality of time periods and determining a characteristic of the analyte sensor using the estimated impedance. The example method may further comprise receiving from the analyte sensor a signal indicative of an analyte concentration, and determining an estimated analyte concentration level using the determined characteristic of the analyte sensor and the received signal.

公开(公告)号：US20240335168A1

公开(公告)日：2024-10-10

申请号：US18627759

申请日：2024-04-05

Applicant: Dexcom, Inc.

Inventor： Qi AN ,  Kevin CHENG ,  Devon M. HEADEN ,  Anita Hanzong SHIEH

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1473

CPC classification number: A61B5/7203 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14735 ,  A61B5/6801 ,  A61B5/7405 ,  A61B5/742 ,  A61B5/7455 ,  A61B2560/045 ,  A61B2560/0468

Abstract: The present disclosure describes a continuous analyte monitoring system that may monitor, generate, and analyze data for analytes (e.g., glucose and/or lactate) and non-enzymes simultaneously. In certain aspects, an analyte sensor system includes a first electrode, a second electrode, and a sensor electronics module. The first electrode generates a first analyte signal stream. The second electrode generates a non-enzyme signal stream indicating a level of a non-enzyme over time. The sensor electronics module determines a level of a first analyte based on the first analyte signal stream and adjusts the level of the first analyte based on the non-enzyme signal stream.

公开(公告)号：US20240335146A1

公开(公告)日：2024-10-10

申请号：US18736041

申请日：2024-06-06

Applicant: Mayo Foundation for Medical Education and Research ,  Arizona Board of Regents on behalf of Arizona State University

Inventor： Marylaura Thomas ,  Leslie Thomas ,  Erica Forzani

IPC: A61B5/1455 ,  A61B5/00 ,  A61B5/145 ,  A61B5/20 ,  B01D53/22

CPC classification number: A61B5/14552 ,  A61B5/14546 ,  A61B5/201 ,  A61B5/4866 ,  B01D53/228 ,  B01D2259/10

Abstract: A system with an analyzer device in fluid communication with a sample of a bodily fluid is configured to chemically or electrochemically convert at least a portion of ammonium (NH4+) contained within the bodily fluid into ammonia (NH3) and dispel the converted ammonia (NH3) into a gas sensing chamber. An ammonia (NH3) sensor located within the gas sensing chamber in conjunction with a processor can quantify an amount of ammonia (NH3) present in the gas sensing chamber in relation to the total ammonia of the bodily fluid.

公开(公告)号：US20240324913A1

公开(公告)日：2024-10-03

申请号：US18621449

申请日：2024-03-29

Applicant: Abbott Diabetes Care, Inc.

Inventor： Zenghe Liu ,  Tram Nguyen ,  Benjamin Feldman

IPC: A61B5/145 ,  G01N27/327

CPC classification number: A61B5/14546 ,  G01N27/3271 ,  G01N27/3277

Abstract: The present invention relates to analyte sensors for use in detecting the concentration of potassium ions in a biological fluid and methods of using the sensors.