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公开(公告)号:US20210045665A1
公开(公告)日:2021-02-18
申请号:US17088381
申请日:2020-11-03
Applicant: DexCom, Inc.
Inventor: Peter C. Simpson , James H. Brauker , Mark C. Brister , Paul V. Goode, JR. , Apurv Ullas Kamath , Aarthi Mahalingam , Jack Pryor , Matthew D. Wightlin
IPC: A61B5/145 , A61B5/1473 , A61B5/1486 , A61B5/00 , A61B5/1495 , A61B5/15 , A61B5/05 , A61B17/34
Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
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公开(公告)号:US10918316B2
公开(公告)日:2021-02-16
申请号:US16528316
申请日:2019-07-31
Applicant: DexCom, Inc.
Inventor: Jack Pryor , Apurv Ullas Kamath , Paul V. Goode, Jr. , James H. Brauker , Aarthi Mahalingam
IPC: A61B5/1473 , A61B5/1495 , A61B5/1486 , A61B5/1468 , A61B5/145 , A61B5/00
Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
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公开(公告)号:US10898113B2
公开(公告)日:2021-01-26
申请号:US16000621
申请日:2018-06-05
Applicant: DexCom, Inc.
Inventor: James H. Brauker , Victoria E. Carr-Brendel , Paul V. Goode, Jr. , Apurv Ullas Kamath , James Patrick Thrower , Ben Xavier
IPC: A61B5/00 , A61B5/145 , A61B5/1468 , A61B5/1486 , A61B5/1495 , A61M5/172 , G06F19/00 , A61B5/1473
Abstract: Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.
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公开(公告)号:US10827956B2
公开(公告)日:2020-11-10
申请号:US16790435
申请日:2020-02-13
Applicant: DexCom, Inc.
Inventor: Mark C. Brister , Peter C. Simpson , Matthew D. Wightlin , Steve Masterson , James R. Petisce , John Nolting , Jack Pryor , Sean Saint , Vance Swanson , James H. Brauker , Apurv Ullas Kamath , Paul V. Goode, Jr. , Aarthi Mahalingam
IPC: A61B5/1468 , A61B5/1486 , A61B5/1473 , A61B5/1495 , A61B5/145 , A61B5/00 , A61B5/15 , A61B5/05 , A61B17/34 , A61M5/172 , A61M5/158 , A61M5/142
Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
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公开(公告)号:US20200337618A1
公开(公告)日:2020-10-29
申请号:US16924117
申请日:2020-07-08
Applicant: DexCom, Inc.
Inventor: Peter C. Simpson , James H. Brauker , Mark C. Brister , Paul V. Goode, JR. , Apurv Ullas Kamath , Aarthi Mahalingam , Jack Pryor , Matthew D. Wightlin
IPC: A61B5/145 , A61B5/1473 , A61B5/1486 , A61B5/00 , A61B5/1495 , A61B5/15 , A61B5/05 , A61B17/34
Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
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公开(公告)号:US20200245917A1
公开(公告)日:2020-08-06
申请号:US16857107
申请日:2020-04-23
Applicant: DexCom, Inc.
Inventor: Peter C. Simpson , Robert J. Boock , Sebastian Bohm , James H. Brauker , Paul V. Neale
IPC: A61B5/1486 , A61B5/1468 , A61B5/1473 , A61B5/145 , A61B5/00
Abstract: A transcutaneous sensor device configured for continuously measuring analyte concentrations in a host is provided. In some embodiments, the transcutaneous sensor device 100 comprises an in vivo portion 160 configured for insertion under the skin 180 of the host and an ex vivo portion 170 configured to remain above the surface of the skin 180 of the host after sensor insertion of the in vivo portion. The in vivo portion may comprise a tissue piercing element 110 configured for piercing the skin 180 of the host and a sensor body 120 comprising a material or support member 130 that provides sufficient column strength to allow the sensor body to be pushable in a host tissue without substantial buckling. The ex vivo portion 170 may be configured to comprise (or operably connect to) a sensor electronics unit and may comprise a mounting unit 150. Also described here are various configurations of the sensor body and the tissue piercing element that may be used to protect the membrane of the sensor body.
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公开(公告)号:US10702193B2
公开(公告)日:2020-07-07
申请号:US16742848
申请日:2020-01-14
Applicant: DexCom, Inc.
Inventor: Peter C. Simpson , James H. Brauker
Abstract: Disclosed herein is an analyte sensing biointerface that comprises a sensing electrode incorporated within a non-conductive matrix comprising a plurality of passageways extending through the matrix to the sensing electrode. Also disclosed herein are methods of manufacturing a sensing biointerface and methods of detecting an analyte within tissue of a host using an analyte sensing biointerface.
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公开(公告)号:US20200146599A1
公开(公告)日:2020-05-14
申请号:US16742848
申请日:2020-01-14
Applicant: DexCom, Inc.
Inventor: Peter C. Simpson , James H. Brauker
IPC: A61B5/145 , C12Q1/00 , A61B5/1486
Abstract: Disclosed herein is an analyte sensing biointerface that comprises a sensing electrode incorporated within a non-conductive matrix comprising a plurality of passageways extending through the matrix to the sensing electrode. Also disclosed herein are methods of manufacturing a sensing biointerface and methods of detecting an analyte within tissue of a host using an analyte sensing biointerface.
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公开(公告)号:US20200085355A1
公开(公告)日:2020-03-19
申请号:US16691252
申请日:2019-11-21
Applicant: DexCom, Inc.
Inventor: Jack Pryor , Apurv Ullas Kamath , Paul V. Goode, Jr. , James H. Brauker
IPC: A61B5/145 , A61B5/1495 , A61B5/1486 , A61B5/00 , A61B5/1473
Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
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公开(公告)号:US20200085354A1
公开(公告)日:2020-03-19
申请号:US16690977
申请日:2019-11-21
Applicant: DexCom, Inc.
Inventor: Jack Pryor , Apurv Ullas Kamath , Paul V. Goode, JR. , James H. Brauker
IPC: A61B5/145 , A61B5/1473 , A61B5/00 , A61B5/1486 , A61B5/1495
Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
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