公开(公告)号：US20210322901A1

公开(公告)日：2021-10-21

申请号：US17262356

申请日：2019-08-12

Applicant: EMD Millipore Corporation

Inventor： Michael James Susienka ,  Jeremy Perreault ,  Joseph Geringer ,  Brian Hillier ,  Joseph Muldoon ,  John Paul Amara

IPC: B01D27/14 ,  B01D35/30 ,  B01D63/08

Abstract: A filtration module is provided, the module including at least one filtration packet containing filtration media or one or more membranes, such as a stack of membranes, the at least one filtration packet having one or more fluid ports, the one or more fluid ports being surrounded by a primary seal and a secondary seal spaced from the primary seal. The secondary seals are designed to maintain sterility of the assembly during shipping, handling and/or installation. A removable film may cover one or more fluid ports to maintain sterility prior to use.

公开(公告)号：US20140231339A1

公开(公告)日：2014-08-21

申请号：US14348968

申请日：2012-12-10

Applicant: EMD Millipore Corporation

Inventor： Clifton Ngan ,  Yu Zou ,  Brian Hillier ,  Andrew Bartlett

IPC: B01D35/28

CPC classification number: B01D35/28 ,  B01D39/083 ,  B01D63/08 ,  B01D2313/10 ,  B01D2313/143 ,  C07K1/34

Abstract: A device for the tangential filtration of liquids at high viscosities is taught. For a given channel length and width (relatively fixed by the cassette design), one can decrease the channel pressure drop by increasing the channel height or reducing the channel hydraulic resistance. One can increase the channel height by using a larger diameter fiber in the screen, by increasing the thickness of the molded border or nm on the overmolded screen or by using a thicker nonwoven as a spacer in a non-overmolded screen. Since the screen is embossed into the surface of the membrane: the effective channel height Is also affected by the hardness of the membrane -as well as the fibers In the screen.

Abstract translation: 教导了用于在高粘度下切向过滤液体的装置。 对于给定的通道长度和宽度（通过盒式设计相对固定），可以通过增加通道高度或降低通道液压阻力来减小通道压降。 可以通过在屏幕中使用较大直径的纤维来增加通道高度，通过增加成型边界的厚度或包覆成型的筛网上的nm，或者通过在非包覆成型的筛网中使用较厚的非织造物作为间隔物来增加通道高度。 由于屏幕被压印到膜的表面：有效通道高度也受到膜的硬度以及屏幕中的纤维的影响。

公开(公告)号：USD811519S1

公开(公告)日：2018-02-27

申请号：US29569589

申请日：2016-06-29

Applicant: EMD Millipore Corporation

Designer： Matthew Natale ,  Brian Hillier

公开(公告)号：US08919365B2

公开(公告)日：2014-12-30

申请号：US13956428

申请日：2013-08-01

Applicant: EMD Millipore Corporation

Inventor： Brian Hillier ,  Martin Szyk ,  Aaron Burke ,  Joseph Almasian

IPC: F16K15/00 ,  F16K31/00 ,  F16K31/50 ,  F16K1/12 ,  F16K11/22 ,  F16K31/44 ,  F16K31/60 ,  G01N15/08

CPC classification number: F16K31/50 ,  F16K1/12 ,  F16K11/22 ,  F16K31/445 ,  F16K31/60 ,  G01N15/0826 ,  Y10T137/0318 ,  Y10T137/7932 ,  Y10T137/794 ,  Y10T137/85938 ,  Y10T137/87885

Abstract: Fluid transfer apparatus including a body having a bore formed through at least a portion of its interior. Contained within the bore is a movable plunger that moves without changing the axial dimensions of the body. A first end of the body contains a face designed to be attached to an upstream component. A second end of the body is connected to a downstream component such as a filter, pipeline, etc. A first end of the plunger, when it is in the closed position, is in alignment with the face of the body, which combined form a steamable surface and a sterile barrier against the environment to the remainder of the interior of the body, the plunger and downstream components. An outer annular collar is rotatable relative to the body and causes the plunger to move axially within the bore from an open to a closed position.

Abstract translation: 流体输送装置包括具有通过其内部的至少一部分形成的孔的主体。 包含在孔内的是可移动的柱塞，其移动而不改变主体的轴向尺寸。 身体的第一端包含设计成连接到上游部件的面。 主体的第二端连接到诸如过滤器，管道等的下游部件。当处于关闭位置时，柱塞的第一端与主体的表面对准，其结合形成一个 可蒸发的表面和抵抗环境的无菌屏障到身体内部的其余部分，柱塞和下游部件。 外环形套环可相对于主体旋转并使柱塞在孔内轴向移动，从开放到闭合位置。

公开(公告)号：US20140026989A1

公开(公告)日：2014-01-30

申请号：US14040777

申请日：2013-09-30

Applicant: EMD Millipore Corporation

Inventor： Brian Hillier ,  Martin Szyk ,  Aaron Burke ,  Joseph Almasian

IPC: F16K31/50

CPC classification number: F16K31/50 ,  F16K1/12 ,  F16K11/22 ,  F16K31/445 ,  F16K31/60 ,  G01N15/0826 ,  Y10T137/0318 ,  Y10T137/7932 ,  Y10T137/794 ,  Y10T137/85938 ,  Y10T137/87885

Abstract: Fluid transfer apparatus including a body having a bore formed through at least a portion of its interior. Contained within the bore is a movable plunger that moves without changing the axial dimensions of the body. A first end of the body contains a face designed to be attached to an upstream component. A second end of the body is connected to a downstream component such as a filter, pipeline, etc. A first end of the plunger, when it is in the closed position, is in alignment with the face of the body, which combined form a steamable surface and a sterile barrier against the environment to the remainder of the interior of the body, the plunger and downstream components. An outer annular collar is rotatable relative to the body and causes the plunger to move axially within the bore from an open to a closed position.

Abstract translation: 流体输送装置包括具有通过其内部的至少一部分形成的孔的主体。 包含在孔内的是可移动的柱塞，其移动而不改变主体的轴向尺寸。 身体的第一端包含设计成连接到上游部件的面。 主体的第二端连接到诸如过滤器，管道等的下游部件。当处于关闭位置时，柱塞的第一端与主体的表面对准，其结合形成一个 可蒸发的表面和抵抗环境的无菌屏障到身体内部的其余部分，柱塞和下游部件。 外环形套环可相对于主体旋转并使柱塞在孔内轴向移动，从开放到闭合位置。