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公开(公告)号：US12076666B2
公开(公告)日：2024-09-03
申请号：US17312109
申请日：2020-03-26
Applicant: EMD Millipore Corporation
Inventor： Akshat Gupta , John Paul Amara , Kara M. Pizzelli , Shannon Ryan
CPC classification number: B01D24/10 , B01D39/1623 , B01D39/18 , B01D39/2068 , G01N1/34 , G01N1/4077 , B01D2201/182 , G01N2001/4088
Abstract: Depth filters with optimized head space are provided, as well as methods of optimizing the head space in depth filters, and methods of filtration with depth filters having optimized head space, including clarification of flocculated feed streams where pretreatment may include any of lowering cell culture pH, addition of polymers (uncharged or charged), or addition of salts to precipitate out solubilized impurities resulting in high insoluble biomass.
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公开(公告)号：USD1018895S1
公开(公告)日：2024-03-19
申请号：US29792704
申请日：2022-04-19
Applicant: EMD Millipore Corporation
Designer： John Paul Amara , James Ormond , Kevin McDermot
Abstract: FIG. 1 is a first perspective view of a disc filter holder of the present invention.
FIG. 2 is a second perspective view of the disc filter holder of the present invention.
FIG. 3 is a third perspective view of the disc filter holder of the present invention.
FIG. 4 is a front view of the disc filter holder of the present invention.
FIG. 5 is a rear view of the disc filter holder of the present invention.
FIG. 6 is a left-side view of the disc filter holder of the present invention.
FIG. 7 is a right-side view of the disc filter holder of the present invention.
FIG. 8 is a top view of the disc filter holder of the present invention.
FIG. 9 is a bottom view of the disc filter holder of the present invention.
FIG. 10 is a first view of the disc filter holder of the present invention in an environmental context holding a disc filter; and,
FIG. 11 is a second view of the disc filter holder of the present invention illustrating an environmental context holding a disc filter in alignment with two other disc filter holders.
The broken lines in FIGS. 1-9 depict portions of the disc filter holder that form no part of the claimed design. The remaining broken lines shown in FIGS. 10-11 depict environmental subject matter and form no part of the claimed design.-
公开(公告)号：US12172108B2
公开(公告)日：2024-12-24
申请号：US17262356
申请日：2019-08-12
Applicant: EMD Millipore Corporation
Inventor： Michael James Susienka , Jeremy Perreault , Joseph Geringer , Brian Hillier , Joseph Muldoon , John Paul Amara
Abstract: A filtration module is provided, the module including at least one filtration packet containing filtration media or one or more membranes, such as a stack of membranes, the at least one filtration packet having one or more fluid ports, the one or more fluid ports being surrounded by a primary seal and a secondary seal spaced from the primary seal. The secondary seals are designed to maintain sterility of the assembly during shipping, handling and/or installation. A removable film may cover one or more fluid ports to maintain sterility prior to use.
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公开(公告)号：US20230302409A1
公开(公告)日：2023-09-28
申请号：US18034243
申请日：2021-11-16
Applicant: EMD Millipore Corporation
Inventor： Heejin Lee , Michael James Susienka , Johnathan Lawson , John Paul Amara , Joseph Michael Almasian , Sean Foley , James Ormond
CPC classification number: B01D61/18 , B01D63/082 , B01D2313/54 , B01D2313/13 , B01D2313/105 , B01D2313/125 , B01D2313/16 , B01D2313/06 , B01D2313/041
Abstract: An apparatus for treating a biological fluid, comprising a plurality of filtration devices. In some embodiments, each of the plurality of filtration devices comprising at least one inlet and at least one outlet; and a first insert plate and a second insert plate opposite the first insert plate, wherein the plurality of filtration devices is disposed therebetween. In some embodiments, each filtration device has a vent port. A manifold for each of the inlets, outlets, and vent ports is optionally fluidly connected. In another embodiment, hose barb connectors or the like may be protected from damage and/or exposure by being recessed in the device or positioned at a periphery of the device. Embodiments include apparatus and methods to achieve dripless connect/disconnect and to reduce the number of sterile-to-sterile connections.
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公开(公告)号：US20230330574A1
公开(公告)日：2023-10-19
申请号：US18185015
申请日：2023-03-16
Applicant: EMD Millipore Corporation
Inventor： John Paul Amara , James Ormond , Kevin McDermot
IPC: B01D35/30
Abstract: The present invention is for a magnetized filter holder.
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Patent Agency Ranking
公开(公告)号：US20210354055A1
公开(公告)日：2021-11-18
申请号：US17312109
申请日：2020-03-26
Applicant: EMD Millipore Corporation
Inventor： Akshat Gupta , John Paul Amara , Kara M. Pizzelli , Shannon Ryan
Abstract: Depth filters with optimized head space are provided, as well as methods of optimizing the head space in depth filters, and methods of filtration with depth filters having optimized head space, including clarification of flocculated feed streams where pretreatment may include any of lowering cell culture pH, addition of polymers (uncharged or charged), or addition of salts to precipitate out solubilized impurities resulting in high insoluble biomass.
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公开(公告)号：US10449517B2
公开(公告)日：2019-10-22
申请号：US15323471
申请日：2015-08-19
Applicant: EMD Millipore Corporation
Inventor： John Paul Amara , John Boyle , David Yavorsky , Benjamin Cacace
IPC: B01J20/285 , B01D15/32 , B01J20/26 , B01J20/28 , B01J20/281 , B01J20/32 , C07K1/16 , B01D15/36 , B01D15/38 , B01J39/19 , B01J47/127 , B01J41/13 , C12N7/00 , B01J39/26 , B01J41/20 , C07K1/18 , C07K1/20 , C07K1/22
Abstract: Chromatography media including a high surface area thermoplastic porous nanofiber and an ion-exchange ligand functionality on the surface of the fiber. The porous nanofibers display a convoluted structure that is comprised of discrete bundles of highly entangled nanofibrils that may be fibrillated or ridged. The porous fibers can be prepared through the extraction of a dissolvable mineral or polymeric porogen that is embedded into the fiber during its manufacture in a melt extrusion process.
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公开(公告)号：US20240269455A1
公开(公告)日：2024-08-15
申请号：US18411879
申请日：2024-01-12
Applicant: EMD Millipore Corporation
Inventor： Heejin Lee , Michael James Susienka , John Paul Amara
CPC classification number: A61M39/18 , A61M39/14 , A61M2205/75
Abstract: A system for sterilizing or bioburden-reducing a filter device includes a breathable microbial barrier, a filter device, and a tubing arrangement. The tubing arrangement may be coupled to at least one opening of the filter device. The tubing arrangement may include an aseptic connector, a sealable component, and a port, all of which are in fluid communication with one another. The sealable component may be disposed in the tubing arrangement between the at least one opening of the filter device and the aseptic connector. The sealable component may be reconfigurable between an open configuration, which facilitates the entry of a sterilization vapor into the tubing arrangement and the filter device when subjected to a sterilization or bioburden reduction process, and a closed configuration, where the tubing arrangement is sealed from a surrounding environment. The breathable microbial barrier may at least partially enclose the port of the tubing arrangement.
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公开(公告)号：US20210322901A1
公开(公告)日：2021-10-21
申请号：US17262356
申请日：2019-08-12
Applicant: EMD Millipore Corporation
Inventor： Michael James Susienka , Jeremy Perreault , Joseph Geringer , Brian Hillier , Joseph Muldoon , John Paul Amara
Abstract: A filtration module is provided, the module including at least one filtration packet containing filtration media or one or more membranes, such as a stack of membranes, the at least one filtration packet having one or more fluid ports, the one or more fluid ports being surrounded by a primary seal and a secondary seal spaced from the primary seal. The secondary seals are designed to maintain sterility of the assembly during shipping, handling and/or installation. A removable film may cover one or more fluid ports to maintain sterility prior to use.
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公开(公告)号：US20170165638A1
公开(公告)日：2017-06-15
申请号：US15323471
申请日：2015-08-19
Applicant: EMD Millipore Corporation
Inventor： John Paul Amara , John Boyle , David Yavorsky , Benjamin Cacace
IPC: B01J20/285 , B01D15/32 , B01D15/38 , B01J47/127 , B01J20/28 , B01J39/19 , B01J41/13 , B01D15/36 , C12N7/00
Abstract: Chromatography media including a high surface area thermoplastic porous nanofiber and an ion-exchange ligand functionality on the surface of the fiber. The porous nanofibers display a convoluted structure that is comprised of discrete bundles of highly entangled nanofibrils that may be fibrillated or ridged. The porous fibers can be prepared through the extraction of a dissolvable mineral or polymeric porogen that is embedded into the fiber during its manufacture in a melt extrusion process.
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