公开(公告)号：US06653153B2

公开(公告)日：2003-11-25

申请号：US09898142

申请日：2001-07-03

申请人： Yusheng Xiong ,  Kevin Chapman ,  Tiebang Wang

发明人： Yusheng Xiong ,  Kevin Chapman ,  Tiebang Wang

IPC分类号： G01N33545

CPC分类号： G01N33/585 ,  B01J2219/00497 ,  B01J2219/005 ,  B01J2219/0054 ,  B01J2219/00572 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00707 ,  B01J2219/0072 ,  C07B2200/11 ,  C40B50/16 ,  C40B70/00 ,  G01N33/54313 ,  Y10T436/182

摘要： A combinatorial library comprises a plurality of ligand-bearing support units, where the ligand-bearing support units comprise (a) a solid carrier, (b) one or more ligands covalently bound to the solid carrier, and (c) one or more encoding metal salts impregnated on the support unit, where the distribution of the cations of the encoding metal salts provides a code for identifying the ligand or ligands that are attached to the support units, and the cations have been stabilized against dissolution by treatment with one or more anions that form insoluble or poorly soluble salts of the cations.