公开(公告)号：US20190030160A1

公开(公告)日：2019-01-31

申请号：US16033489

申请日：2018-07-12

Applicant: Genentech, Inc.

Inventor： Ryan Jefferson Watts ,  Joy Yu Zuchero ,  Jessica Couch ,  Mark Dennis

IPC: A61K39/395 ,  A61K47/68 ,  A61K35/18 ,  C07K16/46 ,  C07K16/28 ,  C07K16/40 ,  C07K16/44 ,  A61K39/00

Abstract: The present invention relates to compositions and methods for improving the safety of blood-brain barrier receptor-mediated blood-brain barrier transport.

公开(公告)号：US20180002433A1

公开(公告)日：2018-01-04

申请号：US15614149

申请日：2017-06-05

Applicant: Genentech, Inc.

Inventor： Yin Zhang ,  Joy Yu Zuchero ,  Jasvinder Atwal ,  Jessica Couch ,  Mark S. Dennis ,  James A. Ernst ,  Ryan J. Watts ,  Gregory A. Lazar

IPC: C07K16/28 ,  A61K47/68 ,  C07K16/40 ,  A61K39/395 ,  A61K45/06 ,  A61K39/00

Abstract: The present invention relates to anti-transferrin receptor antibodies and methods of their use.

公开(公告)号：US09708406B2

公开(公告)日：2017-07-18

申请号：US14283038

申请日：2014-05-20

Applicant: Genentech, Inc.

Inventor： Yin Zhang ,  Joy Yu Zuchero ,  Jasvinder Atwal ,  Jessica Couch ,  Mark S. Dennis ,  James A. Ernst ,  Ryan J. Watts ,  Gregory A. Lazar

IPC: C07K16/40 ,  C07K16/28 ,  A61K39/395 ,  A61K45/06 ,  A61K47/48 ,  A61K39/00

CPC classification number: C07K16/2881 ,  A61K39/3955 ,  A61K45/06 ,  A61K47/6803 ,  A61K47/6849 ,  A61K2039/505 ,  C07K16/40 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/33 ,  C07K2317/41 ,  C07K2317/52 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/71 ,  C07K2317/72 ,  C07K2317/732 ,  C07K2317/92 ,  C07K2317/94

Abstract: The present invention relates to anti-transferrin receptor antibodies and methods of their use.