公开(公告)号：US20200299408A1

公开(公告)日：2020-09-24

申请号：US16790616

申请日：2020-02-13

Applicant: Genentech, Inc.

Inventor： Xiaocheng CHEN ,  Mark S. DENNIS ,  Allen J. EBENS, JR. ,  Teemu T. JUNTTILA ,  Robert F. KELLEY ,  Mary A. MATHIEU

IPC: C07K16/32 ,  C07K16/28 ,  A61K39/395 ,  C07K16/30 ,  A61K45/06 ,  A61K31/573 ,  A61K47/68

Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.

公开(公告)号：US20170234883A1

公开(公告)日：2017-08-17

申请号：US15415379

申请日：2017-01-25

Applicant: Genentech, Inc.

Inventor： Mark S. DENNIS ,  Bonnee RUBINFELD ,  Paul POLAKIS ,  Aya JAKOBOVITS

IPC: G01N33/574 ,  C07K16/40

CPC classification number: G01N33/57434 ,  A61K38/05 ,  A61K39/39558 ,  A61K45/06 ,  A61K47/6851 ,  A61K47/6869 ,  A61K47/6871 ,  A61K49/0002 ,  A61K49/0058 ,  A61K51/1045 ,  A61K51/1072 ,  A61K2039/505 ,  C07K16/30 ,  C07K16/3069 ,  C07K16/40 ,  C07K17/00 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/515 ,  C07K2317/54 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/622 ,  C07K2317/92

Abstract: Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided.