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公开(公告)号:US20180117152A1
公开(公告)日:2018-05-03
申请号:US15836107
申请日:2017-12-08
Applicant: Genentech, Inc.
Inventor: Chingwei Vivian LEE , Mark S. DENNIS , Germaine FUH
IPC: A61K39/395 , C07K16/28 , C07K14/725 , A61P35/00
CPC classification number: A61K39/39558 , A61P35/00 , C07K14/7051 , C07K16/2809 , C07K16/30 , C07K2317/24 , C07K2317/31 , C07K2317/92
Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
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公开(公告)号:US20200299409A1
公开(公告)日:2020-09-24
申请号:US16790656
申请日:2020-02-13
Applicant: Genentech, Inc.
Inventor: Xiaocheng CHEN , Mark S. DENNIS , Allen J. EBENS, Jr. , Teemu T. JUNTTILA , Robert F. KELLEY , Mary A. MATHIEU
IPC: C07K16/32 , C07K16/28 , A61K39/395 , C07K16/30 , A61K45/06 , A61K31/573 , A61K47/68
Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
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公开(公告)号:US20170204194A1
公开(公告)日:2017-07-20
申请号:US15473242
申请日:2017-03-29
Applicant: Genentech, Inc.
Inventor: Xiaocheng CHEN , Mark S. DENNIS , Allen J. EBENS, Jr. , Teemu T. JUNTTILA , Robert F. KELLEY , Mary A. MATHIEU
CPC classification number: C07K16/32 , A61K31/573 , A61K39/39558 , A61K45/06 , A61K47/6881 , A61K2039/505 , C07K16/2809 , C07K16/2827 , C07K16/283 , C07K16/2863 , C07K16/2887 , C07K16/2896 , C07K16/30 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/622 , C07K2317/71 , C07K2317/73 , C07K2317/92
Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
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公开(公告)号:US20180057593A1
公开(公告)日:2018-03-01
申请号:US15787922
申请日:2017-10-19
Applicant: Genentech, Inc.
Inventor: Mark S. DENNIS
IPC: C07K16/28 , C07K16/30 , A61K39/395 , A61K45/06 , A61K31/573
CPC classification number: C07K16/2809 , A61K31/573 , A61K39/39541 , A61K45/06 , A61K2039/505 , A61K2039/507 , A61K2039/54 , C07K16/2887 , C07K16/30 , C07K2317/31 , C07K2317/41 , C07K2317/51 , C07K2317/515 , C07K2317/524 , C07K2317/526 , C07K2317/56 , C07K2317/71 , C07K2317/73 , C07K2318/10 , C07K2319/00 , C07K2319/50
Abstract: The invention provides masked anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
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公开(公告)号:US20150166674A1
公开(公告)日:2015-06-18
申请号:US14517682
申请日:2014-10-17
Applicant: GENENTECH, INC.
Inventor: Mark S. DENNIS , Bonnee RUBINFELD , Paul POLAKIS , Aya JAKOBOVITS
IPC: C07K16/40 , A61K38/05 , A61K47/48 , A61K45/06 , A61K39/395
CPC classification number: G01N33/57434 , A61K38/05 , A61K39/39558 , A61K45/06 , A61K47/6851 , A61K47/6869 , A61K47/6871 , A61K49/0002 , A61K49/0058 , A61K51/1045 , A61K51/1072 , A61K2039/505 , C07K16/30 , C07K16/3069 , C07K16/40 , C07K17/00 , C07K2317/24 , C07K2317/31 , C07K2317/515 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/92
Abstract: Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided.
Abstract translation: 提供抗STEAP-1抗体及其免疫偶联物。 提供了使用抗STEAP-1抗体及其免疫偶联物的方法。
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公开(公告)号:US20150166661A1
公开(公告)日:2015-06-18
申请号:US14574132
申请日:2014-12-17
Applicant: Genentech, Inc.
Inventor: Xiaocheng CHEN , Mark S. DENNIS , Allen J. EBENS, JR. , Teemu T. JUNTTILA , Robert F. KELLEY , Mary A. MATHIEU , Liping L. SUN
IPC: C07K16/28 , A61K31/573 , A61K47/48 , A61K45/06 , A61K39/395 , C07K16/30
CPC classification number: C07K16/32 , A61K31/573 , A61K39/39558 , A61K45/06 , A61K47/6881 , A61K2039/505 , C07K16/2809 , C07K16/2827 , C07K16/283 , C07K16/2863 , C07K16/2887 , C07K16/2896 , C07K16/30 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/622 , C07K2317/71 , C07K2317/73 , C07K2317/92
Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
Abstract translation: 本发明提供分化3(CD3)抗体的抗簇及其使用方法。
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公开(公告)号:US20190112389A1
公开(公告)日:2019-04-18
申请号:US16144452
申请日:2018-09-27
Applicant: Genentech, Inc.
Inventor: Xiaocheng CHEN , Mark S. DENNIS , Allen J. EBENS, JR. , Teemu T. JUNTTILA , Robert F. KELLEY , Mary A. MATHIEU , Liping L. SUN
IPC: C07K16/32 , A61K39/395 , A61K45/06 , A61K47/68 , C07K16/28 , A61K31/573 , C07K16/30
Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
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公开(公告)号:US20190016823A1
公开(公告)日:2019-01-17
申请号:US16144686
申请日:2018-09-27
Applicant: Genentech, Inc.
Inventor: Xiaocheng CHEN , Mark S. DENNIS , Allen J. EBENS, JR. , Teemu T. JUNTTILA , Robert F. KELLEY , Mary A. MATHIEU , Liping L. SUN
IPC: C07K16/32 , A61K31/573 , A61K39/395 , A61K45/06 , A61K47/68 , C07K16/28 , C07K16/30 , A61K39/00
Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
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9.METHODS OF TREATING HER2-POSITIVE CANCERS USING PD-1 AXIS BINDING ANTAGONISTS AND ANTI-HER2 ANTIBODIES 审中-公开
Title translation: 使用PD-1轴结合拮抗剂和抗HER2抗体治疗HER2阳性癌症的方法公开(公告)号:US20170008971A1
公开(公告)日:2017-01-12
申请号:US15184966
申请日:2016-06-16
Applicant: Genentech, Inc.
Inventor: Mark S. DENNIS , Allen EBENS , Bryan IRVING , Teemu T. JUNTTILA , Ji LI
IPC: C07K16/32 , A61K39/395 , A61K45/06 , C07K16/28 , C07K16/30
CPC classification number: C07K16/32 , A61K31/282 , A61K31/337 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K47/643 , A61K2039/505 , A61K2039/507 , C07K16/2803 , C07K16/2809 , C07K16/2818 , C07K16/2827 , C07K16/30 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3069 , C07K2317/24 , C07K2317/31 , C07K2317/41 , C07K2317/52 , C07K2317/524 , C07K2317/526 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2317/94 , A61K2300/00
Abstract: The invention provides compositions and methods for treating HER2-postitive cancers. The method comprising administering a PD-1 axis binding antagonist and an antibody that targets HER2.
Abstract translation: 本发明提供用于治疗HER2-肿瘤的组合物和方法。 该方法包括施用PD-1轴结合拮抗剂和靶向HER2的抗体。
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公开(公告)号:US20210244815A1
公开(公告)日:2021-08-12
申请号:US17229999
申请日:2021-04-14
Applicant: Genentech, Inc.
Inventor: Chingwei Vivian LEE , Mark S. DENNIS , Germaine FUH
IPC: A61K39/395 , C07K16/28 , C07K16/30 , A61P35/00 , C07K14/725
Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
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