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公开(公告)号:US5807713A
公开(公告)日:1998-09-15
申请号:US482577
申请日:1995-06-07
申请人: Gertrud Hotten , Helge Neidhardt , Rolf Bechtold , Jens Pohl
发明人: Gertrud Hotten , Helge Neidhardt , Rolf Bechtold , Jens Pohl
IPC分类号: A61K38/00 , C07K14/495 , C07K14/51 , C12N15/19 , C07K14/52
CPC分类号: C07K14/51 , C07K14/495 , A61K38/00
摘要: The invention concerns a protein of the TGF-.beta. family, the DNA coding therefor and a pharmaceutical composition containing such a protein.
摘要翻译: 本发明涉及TGF-β家族的蛋白质,其编码的DNA和含有这种蛋白质的药物组合物。
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12.Antibody or antibody fragments specific for a protein of the TGF-β family 失效
标题翻译: 对TGF-β家族蛋白质特异的抗体或抗体片段公开(公告)号:US07067637B1
公开(公告)日:2006-06-27
申请号:US09901556
申请日:1999-09-24
申请人: Gertrud Hötten , Helge Neidhardt
发明人: Gertrud Hötten , Helge Neidhardt
IPC分类号: C07K16/24
CPC分类号: A61K38/1858 , A61K38/00 , A61K38/1808 , C07K14/495 , C07K14/51
摘要: The invention provides antibody and antibody fragments which specifically bind to novel members of the TGF-β family of proteins. The TFG-β family comprises proteins which function as growth and/or differentiation factors and which are useful in medical applications. Accordingly, the invention also applies to the production of said antibodies or antibody fragments and a diagnostic method for detecting said proteins of the TGF-β family.
摘要翻译: 本发明提供特异性结合蛋白质的TGF-β家族的新成员的抗体和抗体片段。 TFG-β家族包含用作生长和/或分化因子并且可用于医学应用的蛋白质。 因此,本发明也适用于所述抗体或抗体片段的制备以及用于检测TGF-β家族蛋白的诊断方法。
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公开(公告)号:US5994094A
公开(公告)日:1999-11-30
申请号:US288508
申请日:1994-08-10
IPC分类号: C12N15/09 , A61K38/00 , A61K38/22 , A61K39/395 , A61P1/02 , A61P43/00 , C07H21/04 , C07K14/495 , C07K14/51 , C07K16/22 , C12N5/10 , C12N15/12 , C12P21/02 , C12P21/00 , C12N15/00
摘要: The invention concerns a protein of the TGF-.beta. family, the DNA coding therefor and a pharmaceutical composition containing the protein.
摘要翻译: 本发明涉及TGF-β家族的蛋白质,其编码的DNA和含有蛋白质的药物组合物。
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公开(公告)号:US07642237B2
公开(公告)日:2010-01-05
申请号:US10800917
申请日:2004-03-16
IPC分类号: A61K38/18 , C07K14/51 , C07K14/515
摘要: The invention concerns a protein of the TGF-β family, the DNA coding therefor and a pharmaceutical composition containing the protein.
摘要翻译: 本发明涉及TGF-β家族的蛋白质,其编码的DNA和含有蛋白质的药物组合物。
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