公开(公告)号：US20250059521A1

公开(公告)日：2025-02-20

申请号：US18824208

申请日：2024-09-04

Applicant: ILLUMINA, INC. ,  ILLUMINA CAMBRIDGE LIMITED ,  ILLUMINA SINGAPORE PTE. LTD.

Inventor： Kay Klausing ,  Hamed Tabatabaei Ghomi ,  Misha Golynskiy ,  Saurabh Nirantar ,  Seth McDonald ,  Sergio Peisajovich

IPC: C12N9/12

Abstract: Presented herein are altered polymerase enzymes for improved incorporation of nucleotides and nucleotide analogues, in particular altered polymerases that maintain high fidelity under reduced incorporation times, as well as methods and kits using the same.

公开(公告)号：US12104182B2

公开(公告)日：2024-10-01

申请号：US18120639

申请日：2023-03-13

Applicant: ILLUMINA, INC. ,  ILLUMINA CAMBRIDGE LIMITED ,  ILLUMINA SINGAPORE PTE. LTD.

Inventor： Kay Klausing ,  Hamed Tabatabaei Ghomi ,  Misha Golynskiy ,  Saurabh Nirantar ,  Seth McDonald ,  Sergio Peisajovich

IPC: C12N9/12

CPC classification number: C12N9/1252 ,  C12Y207/07007

Abstract: Presented herein are altered polymerase enzymes for improved incorporation of nucleotides and nucleotide analogues, in particular altered polymerases that maintain high fidelity under reduced incorporation times, as well as methods and kits using the same.

公开(公告)号：US20230357731A1

公开(公告)日：2023-11-09

申请号：US18120639

申请日：2023-03-13

Applicant: ILLUMINA, INC. ,  ILLUMINA CAMBRIDGE LIMITED ,  ILLUMINA SINGAPORE PTE. LTD.

Inventor： Kay Klausing ,  Hamed Tabatabaei Ghomi ,  Misha Golynskiy ,  Saurabh Nirantar ,  Seth McDonald ,  Sergio Peisajovich

IPC: C12N9/12

CPC classification number: C12N9/1252 ,  C12Y207/07007

Abstract: Presented herein are altered polymerase enzymes for improved incorporation of nucleotides and nucleotide analogues, in particular altered polymerases that maintain high fidelity under reduced incorporation times, as well as methods and kits using the same.

公开(公告)号：US11560552B2

公开(公告)日：2023-01-24

申请号：US17397003

申请日：2021-08-09

Applicant: Illumina, Inc. ,  Illumina Singapore Pte. Ltd.

Inventor： Misha Golynskiy ,  Seth McDonald ,  Saurabh Nirantar ,  Matthew Kellinger ,  Michael Previte ,  Sergio Peisajovich ,  Molly He

IPC: C12N9/12 ,  C12N15/52 ,  C12N1/20 ,  C12Q1/68

Abstract: Presented herein are altered polymerase enzymes for improved incorporation of nucleotides and nucleotide analogues, in particular altered polymerases that maintain high fidelity under reduced incorporation times, as well as methods and kits using the same.

公开(公告)号：US20220056424A1

公开(公告)日：2022-02-24

申请号：US17397003

申请日：2021-08-09

Applicant: Illumina, Inc. ,  Illumina Singapore Pte. Ltd.

Inventor： Misha Golynskiy ,  Seth McDonald ,  Saurabh Nirantar ,  Matthew Kellinger ,  Michael Previte ,  Sergio Peisajovich ,  Molly He

IPC: C12N9/12

Abstract: Presented herein are altered polymerase enzymes for improved incorporation of nucleotides and nucleotide analogues, in particular altered polymerases that maintain high fidelity under reduced incorporation times, as well as methods and kits using the same.