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    Method and system for analysing tissue from images
    11.
    发明授权
    Method and system for analysing tissue from images 有权
    用于分析图像组织的方法和系统

    公开(公告)号：US09008382B2

    公开(公告)日：2015-04-14

    申请号：US13261165

    申请日：2010-08-03

    申请人： Ralph Highnam ,  John Michael Brady ,  Nico Karssemeijer ,  Martin Yaffe

    发明人： Ralph Highnam ,  John Michael Brady ,  Nico Karssemeijer ,  Martin Yaffe

    IPC分类号： G06K9/00 ,  G06T7/00 ,  G06T7/40

    CPC分类号： G06T7/0012 ,  G06T7/44 ,  G06T2207/30068

    摘要： Disclosed is a method of analyzing tissue from an image comprising providing an electronic image of tissue (100, 400, 450, 600, 800, 1100), determining a reference value from the image (1070, 1170, 1270), establishing an hint representation (500,700) of the image, and using the hint representation in analysis of the tissue to quantify the breast and compute a calibration error. Also disclosed is a system which runs an inner breast edge detection algorithm (1310) on the electronic image to detect the inner breast edge on the image (1315), and refined the inner breast edge location (1340) if a calibration error is not acceptable (1324). Also disclosed is automatic estimation of breast composition and temporal analysis of images.

    摘要翻译： 公开了一种从图像中分析组织的方法，包括提供组织的电子图像（100,400,450,600,800,10000），从图像（1070,1170,1270）确定参考值，建立提示表示 （500,700）的图像，并且使用提示表示来分析组织以量化乳房并计算校准误差。 还公开了一种在电子图像上运行内部乳房边缘检测算法（1310）以检测图像（1315）上的内乳房边缘的系统，并且如果校准误差不可接受则改善了内乳房边缘位置（1340） （1324）。 还公开了对图像的乳房成分和时间分析的自动估计。

    Imaging Technique and Imaging System
    12.
    发明申请
    Imaging Technique and Imaging System 有权
    成像技术与成像系统

    公开(公告)号：US20140010429A1

    公开(公告)日：2014-01-09

    申请号：US13990181

    申请日：2011-11-29

    申请人： Ralph Highnam ,  John Michael Brady

    发明人： Ralph Highnam ,  John Michael Brady

    IPC分类号： G06T7/00

    CPC分类号： G06T7/0012 ,  G06T7/0014 ,  G06T2207/10088 ,  G06T2207/10136 ,  G06T2207/30068

    摘要： The present invention relates to an imaging technique and an imaging system and more particularly to an automatic assessment of quantitative measure(s)/properties(s) of an object wherein, for example, an imaging system is used to capture an image, following which image properties are quantified using image processing techniques. An imaging technique obtains an image of an object along a first axis, or by way of a first technique, and subsequently obtains an image of the object along a second axis, or by way of a second technique. One or more pixels from the first image are selected and designated as reference pixels. An automated comparison between corresponding regions of the first and second images are then performed which is based upon the reference pixels, so as to indicate regions of interest.

    摘要翻译： 本发明涉及成像技术和成像系统，并且更具体地涉及自动评估对象的定量测量/特性，其中例如使用成像系统来拍摄图像，随后， 图像属性使用图像处理技术进行量化。 成像技术获得沿着第一轴的物体的图像，或者通过第一技术获得物体的图像，并且随后通过第二轴获得物体的图像，或者通过第二技术获得物体的图像。 选择来自第一图像的一个或多个像素并将其指定为参考像素。 然后，基于参考像素执行第一和第二图像的相应区域之间的自动比较，以便指示感兴趣的区域。

    Signal processing method and apparatus
    14.
    发明授权
    Signal processing method and apparatus 有权
    信号处理方法及装置

    公开(公告)号：US08275183B2

    公开(公告)日：2012-09-25

    申请号：US12705831

    申请日：2010-02-15

    申请人： Timor Kadir ,  John Michael Brady

    发明人： Timor Kadir ,  John Michael Brady

    IPC分类号： G06K9/00

    CPC分类号： G06K9/6217 ,  G06F17/18

    摘要： A signal processing method that includes inputting sample values of a signal and considering the signal to have a plurality of portions. For each portion, a predetermined function is fitted to the sample values of that portion of the signal by calculating values of coefficients for that predetermined function. At least one statistical information function is evaluated for the signal to determine statistical information about the signal and the calculated coefficient values are used so that the form of the statistical information function has been determined for the predetermined function used to fit the signal portion and further includes using the statistical information obtained about the signal to process the signal.

    摘要翻译： 一种信号处理方法，包括输入信号的采样值并考虑信号以具有多个部分。 对于每个部分，通过计算该预定函数的系数值，将预定函数拟合到信号的该部分的采样值。 针对信号评估至少一个统计信息功能以确定关于信号的统计信息，并且使用所计算的系数值，使得已经针对用于拟合信号部分的预定函数确定统计信息功能的形式，并且还包括 使用获得的关于信号的统计信息来处理信号。

    Method and system for analysing tissue from images
    15.
    发明申请
    Method and system for analysing tissue from images 有权
    用于分析图像组织的方法和系统

    公开(公告)号：US20120189175A1

    公开(公告)日：2012-07-26

    申请号：US13261165

    申请日：2010-08-03

    申请人： Ralph Highnam ,  John Michael Brady ,  Nico Karssemeijer ,  Martin Yaffe

    发明人： Ralph Highnam ,  John Michael Brady ,  Nico Karssemeijer ,  Martin Yaffe

    IPC分类号： G06K9/00

    CPC分类号： G06T7/0012 ,  G06T7/44 ,  G06T2207/30068

    摘要： Disclosed is a method of analysing tissue from an image comprising providing an electronic image of tissue (100, 400, 450, 600, 800, 1100), determining a reference value from the image (1070, 1170, 1270), establishing an hint representation (500,700) of the image, and using the hint representation in analysis of the tissue to quantify the breast and compute a calibration error. Also disclosed is a system which runs an inner breast edge detection algorithm (1310) on the electronic image to detect the inner breast edge on the image (1315), and refined the inner breast edge location (1340) if a calibration error is not acceptable (1324). Also disclosed is automatic estimation of breast composition and temporal analysis of images.

    摘要翻译： 公开了一种从图像中分析组织的方法，包括提供组织的电子图像（100,400,450,600,800,10000），从图像（1070,1170,1270）确定参考值，建立提示表示 （500,700）的图像，并且使用提示表示来分析组织以量化乳房并计算校准误差。 还公开了一种在电子图像上运行内部乳房边缘检测算法（1310）以检测图像（1315）上的内乳房边缘的系统，并且如果校准误差不可接受则改善了内乳房边缘位置（1340） （1324）。 还公开了对图像的乳房成分和时间分析的自动估计。

    Three-dimensional reconstructions of a breast from two X-ray mammographics
    18.
    发明授权
    Three-dimensional reconstructions of a breast from two X-ray mammographics 有权
    来自两个X射线乳房摄影术的乳房三维重建

    公开(公告)号：US07519212B2

    公开(公告)日：2009-04-14

    申请号：US10221778

    申请日：2001-01-31

    申请人： John Michael Brady ,  Ralph Highnam ,  Shuk Wah Margaret Yam

    发明人： John Michael Brady ,  Ralph Highnam ,  Shuk Wah Margaret Yam

    IPC分类号： G06K9/00 ,  A61B6/04 ,  A61B8/00

    CPC分类号： G06T7/0012 ,  G06T7/55 ,  G06T2207/30068

    摘要： Methods are described for the production of a three-dimensional reconstruction of a undeformed object from two different views of the object under deformation using a volume constraint and also by matching corresponding features in the two images. The volume constraint involves assuming that the deformed volume is the same as the undeformed volume, and calculating the deformed volume from one of the images. Further, the deformation of the object can be parameterised by finding corresponding image entities in the each of the images. The method is particularly applicable to breast mammograms in which case the two images are the cranio-caudal (CC) image and medio-lateral oblique (MLO) image whose angular separation varies from 35 to 60 degrees. The image entities which are detected in the two images are microcalcifications, and these are matched by detecting a value representing their volume a looking for matches in this value between the two images.

    摘要翻译： 描述了用于使用体积约束从变形的对象的两个不同视图以及通过匹配两个图像中的对应特征来生成未变形对象的三维重建的方法。 体积约束假设变形的体积与未变形的体积相同，并且从一个图像计算变形的体积。 此外，可以通过在每个图像中找到对应的图像实体来参数化对象的变形。 该方法特别适用于乳房X线照片，在这种情况下，两幅图像是角度分离从35度到60度变化的颅尾（CC）图像和中 - 内倾斜（MLO）图像。 在两个图像中检测到的图像实体是微钙化，并且通过检测表示它们的体积的值来匹配这些图像，以在两个图像之间的该值中寻找匹配。

    X-ray image processing
    19.
    发明授权
    X-ray image processing 失效
    X射线图像处理

    公开(公告)号：US07315640B1

    公开(公告)日：2008-01-01

    申请号：US09914460

    申请日：2000-02-21

    申请人： John Michael Brady ,  Ralph Highnam

    发明人： John Michael Brady ,  Ralph Highnam

    IPC分类号： G06K9/00

    CPC分类号： G06T5/002 ,  G06T5/003 ,  G06T2207/10116 ,  G06T2207/30068

    摘要： A method of enhancing and normalizing x-ray images, particularly mammograms, by correcting the image for digitizer blur, glare from the intensifying screen and the anode-heel effect. The method also allows the calculation of the compressed thickness of the imaged breast and calculation of the contribution to the mammograms of the extra focal radiation. The correction of the image for glare from the intensifying screen allows the detection of noise, such as film shot noise, in the image, and in particular the differentiation between such noise and microcalcifications.

    摘要翻译： 通过校正数字化仪模糊的图像，来自增强屏幕的眩光和阳极 - 脚跟效应来增强和归一化X射线图像，特别是乳房X线照片的方法。 该方法还允许计算成像乳房的压缩厚度并计算对额外焦点辐射的乳房X线照片的贡献。 来自增强屏幕的用于眩光的图像的校正允许检测图像中的噪声，例如胶片拍摄噪声，并且特别地，这种噪声和微钙化之间的差异。

    Comparing images
    20.
    发明授权
    Comparing images 有权
    比较图像

    公开(公告)号：US07260254B2

    公开(公告)日：2007-08-21

    申请号：US10303225

    申请日：2002-11-25

    申请人： Ralph Philip Highnam ,  Peter Eric Taylor ,  Bruno Ancelin ,  John Michael Brady

    发明人： Ralph Philip Highnam ,  Peter Eric Taylor ,  Bruno Ancelin ,  John Michael Brady

    IPC分类号： G06K9/00

    CPC分类号： G06T7/0012 ,  G06T2207/30068

    摘要： Comparing first and second images taken on different imaging systems and under different exposure conditions is achieved by the steps of: applying a model to the data representing the first image, which model simulates at least one process step in the creation of said first image, to derive a representation of the first image at a level of processing common to the creation of the second image; and applying a further model to said representation, which model simulates at least one process step in the creation of said second image, to derive a further representation of the first image which corresponds to the same level of processing as said second image.

    摘要翻译： 比较在不同成像系统和不同曝光条件下拍摄的第一和第二图像是通过以下步骤实现的：将模型应用于表示第一图像的数据，该模型模拟创建所述第一图像中的至少一个处理步骤， 在第二图像的创建共同的处理级别上导出第一图像的表示; 以及将另外的模型应用于所述表示，所述模型模拟所述第二图像的创建中的至少一个处理步骤，以导出对应于与所述第二图像相同的处理级别的第一图像的另外的表示。