公开(公告)号：US20070213401A1

公开(公告)日：2007-09-13

申请号：US11687978

申请日：2007-03-19

申请人： David Dooley ,  Charles Taylor, Jr. ,  Andrew Thorpe ,  Fong Wang ,  David Wustrow

发明人： David Dooley ,  Charles Taylor, Jr. ,  Andrew Thorpe ,  Fong Wang ,  David Wustrow

IPC分类号： A61K31/195

CPC分类号： A61K31/662 ,  A61K31/00 ,  A61K31/16 ,  A61K31/18 ,  A61K31/185 ,  A61K31/195 ,  A61K31/197 ,  A61K31/198 ,  A61K31/20 ,  A61K31/401 ,  A61K31/4015 ,  A61K31/41 ,  A61K31/4245 ,  A61K31/433 ,  A61K45/06

摘要： The invention relates to a method of treating central nervous system disorders and other disorders by administering an alpha2delta ligand such as, for example, a compound of the formula or a pharmaceutically acceptable salt thereof, wherein R1 is hydrogen or straight or branched lower alkyl, and n is an integer of from 4 to 6.

公开(公告)号：US20060154972A1

公开(公告)日：2006-07-13

申请号：US11375318

申请日：2006-03-14

申请人： Nancy Barta ,  Jacob Schwarz ,  Andrew Thorpe ,  David Wustrow

发明人： Nancy Barta ,  Jacob Schwarz ,  Andrew Thorpe ,  David Wustrow

IPC分类号： A61K31/44 ,  A61K31/198 ,  A61K31/277

CPC分类号： C07C229/08 ,  A61K31/195 ,  A61K31/198 ,  C07C229/28 ,  C07C229/34 ,  C07C2601/02 ,  C07C2601/04 ,  C07C2601/08 ,  C07C2601/14 ,  Y02A50/415

摘要： This invention relates to certain β-amino acids that bind to the alpha-2-delta (α2δ) subunit of a calcium channel. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorders.