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    METHOD OF DETECTION OF SEVERE ACUTE RESPIRATORY SYNDROME (SARS)-COVID (SARS-CoV)
    11.
    发明申请
    METHOD OF DETECTION OF SEVERE ACUTE RESPIRATORY SYNDROME (SARS)-COVID (SARS-CoV) 有权

    公开(公告)号：US20250062038A1

    公开(公告)日：2025-02-20

    申请号：US18451410

    申请日：2023-08-17

    Applicant: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS

    Inventor： Amjad Bajes KHALIL ,  Muhammad NAEEM ,  Hanoof Fahad ALKHODAIRY ,  Aasif HELAL

    IPC: G16H50/80 ,  G01N33/58

    Abstract: A method of detecting SARS-COV in a sample includes contacting a metal-organic framework with at least one fluorophore-labeled single-stranded probe deoxyribose nucleic acid (DNA) to form a biosensor. The metal-organic framework of the method is zeolitic imidazolate framework-8 (ZIF-8), and the fluorophore-labeled single-stranded probe DNA (p-DNA) has a fluorescence signal at 513 to 517 nm. The method further includes contacting the sample with the biosensor in a solution, and the sample comprises a target sequence of SARS-COV. The target sequence of SARS-COV and the fluorophore-labeled single-stranded p-DNA of the method hybridize to form a double-stranded product. Following the step of the hybridization forming the double-stranded product, the method includes detecting the double-stranded product by observing a change in fluorescence.

    METHOD FOR ANALYZING AQUEOUS SOLUTION WITH MOF CHEMOSENSOR
    12.
    发明申请
    METHOD FOR ANALYZING AQUEOUS SOLUTION WITH MOF CHEMOSENSOR 有权

    公开(公告)号：US20250035546A1

    公开(公告)日：2025-01-30

    申请号：US18913676

    申请日：2024-10-11

    Applicant: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS

    Inventor： Aasif HELAL ,  Muhammed NAEEM ,  Mohammed FETTOUHI ,  Md. Hasan ZAHIR

    IPC: G01N21/3577 ,  G01N21/17

    Abstract: A method of detecting Hg2+ ions in an aqueous solution is described. The method includes contacting the aqueous solution with a metal-organic framework (MOF) chemosensor composite to form a mixture and monitoring a change in an absorption and/or a fluorescence profile of the MOF chemosensor composite in the mixture to determine a presence or absence of Hg2+ ions in the aqueous solution. The MOF chemosensor composite includes fluorescein hydrazide (FH); and a MOF, including nickel as a metal ion and at least one trimesic acid (BTC) ligand. A hydrazide group on the fluorescein hydrazide coordinates to the metal ion of the MOF.

    METHOD OF FIXATING CARBON DIOXIDE TO SUBSTITUTED OXAZOLIDINONES
    13.
    发明申请
    METHOD OF FIXATING CARBON DIOXIDE TO SUBSTITUTED OXAZOLIDINONES 有权

    公开(公告)号：US20240400524A1

    公开(公告)日：2024-12-05

    申请号：US18329092

    申请日：2023-06-05

    Applicant: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS

    Inventor： Aasif HELAL

    IPC: C07D263/04 ,  C07D239/00 ,  C07D263/06 ,  C07D263/58

    Abstract: A method of fixating carbon dioxide (CO2) to form a substituted oxazolidinone is described. The method includes mixing a metal-organic framework (MOF), at least one epoxide, and at least one aromatic amine to form a mixture. The method further includes contacting the mixture with a gas stream containing CO2 to react the CO2 in the gas stream with the epoxide and the aromatic amine to form a substituted oxazolidinone. The MOF is a MIL-68(In)-X MOF. X is of formula (I): where at least one of R1 to R4 is an amine-containing group, and R1 to R4 are independently an amine-containing group or a hydrogen.

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