公开(公告)号：US10059717B2

公开(公告)日：2018-08-28

申请号：US15674023

申请日：2017-08-10

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Tae Bo Sim ,  Woo Young Hur ,  Ho Jong Yoon ,  Chi Man Song ,  Eun Hye Ju ,  Han na Cho ,  Hwan Geun Choi

IPC: C07D487/04 ,  C07D403/14 ,  C07D401/14 ,  A61K31/4985 ,  A61P35/00 ,  A61P35/02

CPC classification number: C07D487/04 ,  C07D401/14 ,  C07D403/14

Abstract: The present invention provides a pharmaceutical composition, as an effective ingredient, a urea compound having a protein kinase inhibitory activity and containing a 3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one skeleton, and a pharmaceutically acceptable salt thereof.

公开(公告)号：US10040803B2

公开(公告)日：2018-08-07

申请号：US15821962

申请日：2017-11-24

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Tae Bo Sim ,  Ho Jong Yoon ,  In Jae Shin ,  Yun Ju Nam ,  Hwan Geun Choi

IPC: C07D495/02 ,  C07D495/04 ,  A61P35/00

CPC classification number: C07D495/04 ,  A61P35/00

Abstract: The present invention relates to a novel 4-((2-acrylamidophenyl)amino)thieno[3,2-d]pyrimidine-7-carboxamide compound, an anticancer agent containing the compound as an active ingredient and an intermediate compound for preparing the compound.