公开(公告)号：US20170087230A1

公开(公告)日：2017-03-30

申请号：US15311093

申请日：2015-05-13

Applicant: MERIAL INC. ,  VITAMFERO S.A ,  L'UNIVERSITE DE BOURGOGNE ,  L'Institut National Superieur des Sciences Agronomiques de L'Alimentation et de L'Environmen

Inventor： Noel Yves Henri Jean Genin ,  Jean-Christophe Audonnet ,  Didier Roy ,  Edouard Seche ,  Patrick Gervais ,  Samira Khaldi-Plassart ,  Romain Useo ,  Joelle DeConinck

IPC: A61K39/002 ,  A61K9/19 ,  A01N1/02

CPC classification number: A61K39/002 ,  A01N1/02 ,  A01N1/0221 ,  A01N1/0278 ,  A01N1/0284 ,  A61K9/0019 ,  A61K9/19 ,  A61K2039/522 ,  Y02A50/41 ,  Y02A50/412

Abstract: The present invention relates generally to the fields of immunology and vaccine technology. More specifically, the present invention relates to methods for freeze-drying biological preparations, including peptides, antigens, antibodies, and especially, cells. Importantly, the disclosed methods preserve the viability, infectivity and immunogenicity of cells from the Apicomplexa phylum, the Sarcocystidae family, and in particular, cells from the Toxoplasma genus.