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公开(公告)号：US20210228883A1
公开(公告)日：2021-07-29
申请号：US16752224
申请日：2020-01-24
Applicant: Medtronic, Inc.
Inventor： Rene A. Molina , Robert S. Raike , Scott R. Stanslaski
Abstract: Techniques, systems, and devices are disclosed for delivering stimulation therapy to a patient. In one example, a medical device determines a first set of stimulation parameters that define entrainment stimulation pulses configured to entrain electrical activity in a patient. The medical device may control a stimulation generator to generate the entrainment stimulation pulses according to the first set of stimulation parameters. The medical device may further determine a second set of stimulation parameters that define at least one desynchronization stimulation pulse configured to disrupt at least a portion of the electrical activity entrained by the entrainment stimulation pulses. The medical device may subsequently control the stimulation generator to generate the desynchronization stimulation pulse(s) according to the second set of stimulation parameters.
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公开(公告)号：US12168133B2
公开(公告)日：2024-12-17
申请号：US18298179
申请日：2023-04-10
Applicant: Medtronic, Inc.
Inventor： Rene A. Molina , Scott R. Stanslaski , Jadin C. Jackson , Christopher L Pulliam , Eric J. Panken , Michelle A. Case , Abbey Beuning Holt Becker
Abstract: Devices, systems, and techniques are described for identifying stimulation parameter values based on electrical stimulation that induces dyskinesia for the patient. For example, a method may include controlling, by processing circuitry, a medical device to deliver electrical stimulation to a portion of a brain of a patient, receiving, by the processing circuitry, information representative of an electrical signal sensed from the brain after delivery of the electrical stimulation, determining, by the processing circuitry and from the information representative of the electrical signal, a peak in a spectral power of the electrical signal at a second frequency lower than a first frequency of the electrical stimulation, and responsive to determining the peak in the spectral power of the electrical signal at the second frequency, performing, by the processing circuitry, an action.
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公开(公告)号：US20240382759A1
公开(公告)日：2024-11-21
申请号：US18786300
申请日：2024-07-26
Applicant: Medtronic, Inc.
Inventor： Benjamin P. Isaacson , David E. Linde , Scott R. Stanslaski , Christopher L. Pulliam , Rene A. Molina , Abbey Beuning Holt Becker , David L. Carlson , Nicholas D. Buse , Duane L. Bourget , Thaddeus S. Brink
Abstract: An example method includes determining, by an implantable medical device (IMD), an electrode of a plurality of electrodes of a lead to be used to deliver electrical stimulation to a patient at a particular time; selecting, by the IMD and based on the determined electrode, a set of electrodes of the plurality of electrodes; and sensing, by the IMD and via the selected set of electrodes, electrical signals of the patient at the particular time.
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公开(公告)号：US11975200B2
公开(公告)日：2024-05-07
申请号：US17651500
申请日：2022-02-17
Applicant: Medtronic, Inc.
Inventor： Jadin C. Jackson , Rene A. Molina , Christopher L. Pulliam
CPC classification number: A61N1/36192 , A61N1/0534 , A61N1/36135 , A61N1/36164 , A61N1/36171 , A61N1/36175 , A61N1/3727
Abstract: Devices, systems, and techniques are disclosed for managing electrical stimulation therapy and/or sensing of physiological signals such as brain signals. For example, a system is configured to receive, for each electrode combination of a plurality of electrode combinations, information representing a signal sensed in response to first electrical stimulation delivered to a patient via a lead, wherein the plurality of electrode combinations comprise different electrode combinations comprising electrode disposed at different positions around a perimeter of the lead implanted in the patient. The system may also be configured to determine, based on the information for each electrode combination of the plurality of electrode combinations, values for a threshold at different locations around the perimeter of the lead and determine, based on the values for the threshold, one or more stimulation parameter values that at least partially define second electrical stimulation deliverable to the patient via the lead.
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公开(公告)号：US20230241400A1
公开(公告)日：2023-08-03
申请号：US18298179
申请日：2023-04-10
Applicant: Medtronic, Inc.
Inventor： Rene A. Molina , Scott R. Stanslaski , Jadin C. Jackson , Christopher L. Pulliam , Eric J. Panken , Michelle A. Case , Abbey Beuning Holt Becker
CPC classification number: A61N1/36139 , A61N1/36135 , A61N1/36067 , A61N1/36171 , A61N1/0534 , A61N1/3615
Abstract: Devices, systems, and techniques are described for identifying stimulation parameter values based on electrical stimulation that induces dyskinesia for the patient. For example, a method may include controlling, by processing circuitry, a medical device to deliver electrical stimulation to a portion of a brain of a patient, receiving, by the processing circuitry, information representative of an electrical signal sensed from the brain after delivery of the electrical stimulation, determining, by the processing circuitry and from the information representative of the electrical signal, a peak in a spectral power of the electrical signal at a second frequency lower than a first frequency of the electrical stimulation, and responsive to determining the peak in the spectral power of the electrical signal at the second frequency, performing, by the processing circuitry, an action.
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Patent Agency Ranking
公开(公告)号：US20230166111A1
公开(公告)日：2023-06-01
申请号：US18051421
申请日：2022-10-31
Applicant: Medtronic, Inc.
Inventor： Kristin N. Hageman , Scott R. Stanslaski , Erik J. Peterson , Rene A. Molina , Paul H. Stypulkowski , David A. Dinsmoor , Leonid M. Litvak , Michelle A. Case
CPC classification number: A61N1/36139 , A61N1/0534 , A61N1/36146
Abstract: A system includes memory and processing circuitry coupled to the memory and configured to determine a plurality of local field potential (LFP) measurements of an LFP, wherein the LFP is intrinsically generated by a signal source within a brain of a patient, determine one or more electrodes for delivering a therapeutic electrical stimulation signal based on the LFP measurements, control stimulation generation circuitry to deliver a plurality of electrical stimulation signals via the determined one or more electrodes, wherein the plurality of electrical stimulation signals each comprise at least one different therapy parameter, for respective ones of the plurality of electrical stimulation signals, determine respective evoked signals, wherein the respective evoked signals are evoked by delivery of the respective plurality of electrical stimulation signals, and determine at least one parameter for the therapeutic electrical stimulation signal based on the respective evoked signals.
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公开(公告)号：US20220032059A1
公开(公告)日：2022-02-03
申请号：US16945639
申请日：2020-07-31
Applicant: Medtronic, Inc.
Inventor： Rene A. Molina , Scott R. Stanslaski , Jadin C. Jackson , Christopher L. Pulliam , Eric J. Panken , Michelle A. Case , Abbey Beuning Holt Becker
Abstract: Devices, systems, and techniques are described for identifying stimulation parameter values based on electrical stimulation that induces dyskinesia for the patient. For example, a method may include controlling, by processing circuitry, a medical device to deliver electrical stimulation to a portion of a brain of a patient, receiving, by the processing circuitry, information representative of an electrical signal sensed from the brain after delivery of the electrical stimulation, determining, by the processing circuitry and from the information representative of the electrical signal, a peak in a spectral power of the electrical signal at a second frequency lower than a first frequency of the electrical stimulation, and responsive to determining the peak in the spectral power of the electrical signal at the second frequency, performing, by the processing circuitry, an action.
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公开(公告)号：US20240285954A1
公开(公告)日：2024-08-29
申请号：US18656073
申请日：2024-05-06
Applicant: Medtronic, Inc.
Inventor： Jadin C. Jackson , Rene A. Molina , Christopher L. Pulliam
CPC classification number: A61N1/36192 , A61N1/0534 , A61N1/36135 , A61N1/36164 , A61N1/36171 , A61N1/36175 , A61N1/3727
Abstract: Devices, systems, and techniques are disclosed for managing electrical stimulation therapy and/or sensing of physiological signals such as brain signals. For example, a system is configured to receive, for each electrode combination of a plurality of electrode combinations, information representing a signal sensed in response to first electrical stimulation delivered to a patient via a lead, wherein the plurality of electrode combinations comprise different electrode combinations comprising electrode disposed at different positions around a perimeter of the lead implanted in the patient. The system may also be configured to determine, based on the information for each electrode combination of the plurality of electrode combinations, values for a threshold at different locations around the perimeter of the lead and determine, based on the values for the threshold, one or more stimulation parameter values that at least partially define second electrical stimulation deliverable to the patient via the lead.
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公开(公告)号：US20230110685A1
公开(公告)日：2023-04-13
申请号：US17934360
申请日：2022-09-22
Applicant: Medtronic, Inc.
Inventor： Rene A. Molina , Abbey Beuning Holt Becker
IPC: A61N1/36
Abstract: This disclosure is directed to devices, systems, and techniques for delivering electrical stimulation. In some examples, a system includes processing circuitry configured to: receive information representative of a bioelectric brain signal recorded from a brain of a patient; and determine, based on the information, at least one pathological frequency of the bioelectric brain signal. Additionally, the processing circuitry is configured to select, based on the at least one pathological frequency, a sequence of pulse bursts at a pulse burst frequency, the sequence of pulse bursts at least partially defining electrical stimulation deliverable to an area of a brain of a patient, wherein adjacent pulse bursts within the sequence comprise different intra-burst pulse frequencies; and control a medical device to deliver the electrical stimulation comprising the sequence of pulse bursts to the area of the brain of the patient.
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公开(公告)号：US11623096B2
公开(公告)日：2023-04-11
申请号：US16945624
申请日：2020-07-31
Applicant: Medtronic, Inc.
Inventor： Rene A. Molina , Scott R. Stanslaski , Jadin C. Jackson , Christopher L. Pulliam , Eric J. Panken , Michelle A. Case , Abbey Beuning Holt Becker
Abstract: Devices, systems, and techniques are described for identifying stimulation parameter values based on electrical stimulation that induces dyskinesia for the patient. For example, a method may include controlling, by processing circuitry, a medical device to deliver electrical stimulation to a portion of a brain of a patient, receiving, by the processing circuitry, information representative of an electrical signal sensed from the brain after delivery of the electrical stimulation, determining, by the processing circuitry and from the information representative of the electrical signal, a peak in a spectral power of the electrical signal at a second frequency lower than a first frequency of the electrical stimulation, and responsive to determining the peak in the spectral power of the electrical signal at the second frequency, performing, by the processing circuitry, an action.
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