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公开(公告)号：US11475998B2
公开(公告)日：2022-10-18
申请号：US16851500
申请日：2020-04-17
Applicant: Medtronic, Inc.
Inventor： Donald R. Musgrove , Niranjan Chakravarthy , Siddharth Dani , Tarek D. Haddad , Andrew Radtke , Rodolphe Katra , Lindsay A. Pedalty
Abstract: Techniques are disclosed for preparing data for use in artificial intelligence (AI)-based cardiac arrhythmia detection. In accordance with the techniques of this disclosure, a computing system may obtain a cardiac electrogram (EGM) strip that represents a waveform of a cardiac rhythm of a same patient. Additionally, the computing system may preprocess the cardiac EGM strip. The computing system may then apply a deep learning model to the preprocessed cardiac EGM strip to generate arrhythmia data indicating whether the cardiac EGM strip represents one or more occurrences of one or more cardiac arrhythmias.
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公开(公告)号：US20210338134A1
公开(公告)日：2021-11-04
申请号：US17373480
申请日：2021-07-12
Applicant: Medtronic, Inc.
Inventor： Niranjan Chakravarthy , Siddharth Dani , Tarek D. Haddad , Donald R. Musgrove , Andrew Radtke , Eduardo N. Warman , Rodolphe Katra , Lindsay A. Pedalty
Abstract: Techniques are disclosed for using both feature delineation and machine learning to detect cardiac arrhythmia. A computing device receives cardiac electrogram data of a patient sensed by a medical device. The computing device obtains, via feature-based delineation of the cardiac electrogram data, a first classification of arrhythmia in the patient. The computing device applies a machine learning model to the received cardiac electrogram data to obtain a second classification of arrhythmia in the patient. As one example, the computing device uses the first and second classifications to determine whether an episode of arrhythmia has occurred in the patient. As another example, the computing device uses the second classification to verify the first classification of arrhythmia in the patient. The computing device outputs a report indicating that the episode of arrhythmia has occurred and one or more cardiac features that coincide with the episode of arrhythmia.
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13.发明申请公开(公告)号：US20200164212A1
公开(公告)日：2020-05-28
申请号：US16774418
申请日：2020-01-28
Applicant: Medtronic, Inc.
Inventor： Ashutosh Chaturvedi , Siddharth Dani , Timothy J. Denison , William F. Kaemmerer , Shahram Malekkhosravi , Eric J. Panken , Brandon Zingsheim
IPC: A61N1/36 , G16H50/50 , A61B5/00 , A61B5/0478 , A61N1/372
Abstract: In some examples, a processor of a system evaluates a therapy program based on a score determined based on a volume of tissue expected to be activated (“VTA”) by therapy delivery according to the therapy program. The score may be determined using an efficacy map comprising a plurality of voxels that are each assigned a value. In some examples, the efficacy map is selected from a plurality of stored efficacy maps based on a patient condition, one or more patient symptoms, or both the patient condition and one or more patient symptoms. In addition, in some examples, voxels of the efficacy map are assigned respective values that are associated with a clinical rating scale.
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公开(公告)号：US12036414B2
公开(公告)日：2024-07-16
申请号：US15342167
申请日：2016-11-03
Applicant: Medtronic, Inc.
Inventor： William F. Kaemmerer , Siddharth Dani , Allison T. Connolly
CPC classification number: A61N1/36185 , A61N1/0534 , A61N1/36064 , A61N1/36067 , A61N1/36075 , A61N1/36096 , A61N1/36139 , A61N1/37247 , A61N1/37235
Abstract: In one example, a method includes selecting, by one or more processors and based on a representation of sensed electrical signals for a particular patient and a plurality of representations of sensed electrical signals for a plurality of other patients, a combination of electrodes of a plurality of combinations of one or more implantable electrodes for delivery of electrical stimulation to the particular patient.
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公开(公告)号：US20230329624A1
公开(公告)日：2023-10-19
申请号：US18336161
申请日：2023-06-16
Applicant: Medtronic, Inc.
Inventor： Lindsay A. Pedalty , Niranjan Chakravarthy , Rodolphe Katra , Tarek D. Haddad , Andrew Radtke , Siddharth Dani , Donald R. Musgrove
CPC classification number: A61B5/361 , A61B5/7264 , A61B5/742 , A61B5/7405 , A61B5/316 , A61B5/322 , A61B5/352 , A61B5/363 , A61B5/346
Abstract: Techniques are disclosed for explaining and visualizing an output of a machine learning system that detects cardiac arrhythmia in a patient. In one example, a computing device receives cardiac electrogram data sensed by a medical device. The computing device applies a machine learning model, trained using cardiac electrogram data for a plurality of patients, to the received cardiac electrogram data to determine, based on the machine learning model, that an episode of arrhythmia has occurred in the patient and a level of confidence in the determination that the episode of arrhythmia has occurred in the patient. In response to determining that the level of confidence is greater than a predetermined threshold, the computing device displays, to a user, a portion of the cardiac electrogram data, an indication that the episode of arrhythmia has occurred, and an indication of the level of confidence that the episode of arrhythmia has occurred.
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Patent Agency Ranking
公开(公告)号：US11723577B2
公开(公告)日：2023-08-15
申请号：US16850749
申请日：2020-04-16
Applicant: Medtronic, Inc.
Inventor： Lindsay A. Pedalty , Niranjan Chakravarthy , Rodolphe Katra , Tarek D. Haddad , Andrew Radtke , Siddharth Dani , Donald R. Musgrove
CPC classification number: A61B5/361 , A61B5/316 , A61B5/322 , A61B5/346 , A61B5/352 , A61B5/363 , A61B5/7264 , A61B5/742 , A61B5/7405
Abstract: Techniques are disclosed for explaining and visualizing an output of a machine learning system that detects cardiac arrhythmia in a patient. In one example, a computing device receives cardiac electrogram data sensed by a medical device. The computing device applies a machine learning model, trained using cardiac electrogram data for a plurality of patients, to the received cardiac electrogram data to determine, based on the machine learning model, that an episode of arrhythmia has occurred in the patient and a level of confidence in the determination that the episode of arrhythmia has occurred in the patient. In response to determining that the level of confidence is greater than a predetermined threshold, the computing device displays, to a user, a portion of the cardiac electrogram data, an indication that the episode of arrhythmia has occurred, and an indication of the level of confidence that the episode of arrhythmia has occurred.
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公开(公告)号：US11583687B2
公开(公告)日：2023-02-21
申请号：US16850833
申请日：2020-04-16
Applicant: Medtronic, Inc.
Inventor： Siddharth Dani , Tarek D. Haddad , Donald R. Musgrove , Andrew Radtke , Niranjan Chakravarthy , Rodolphe Katra , Lindsay A. Pedalty
Abstract: Techniques are disclosed for monitoring a patient for the occurrence of a cardiac arrhythmia. A computing system generates sample probability values by applying a machine learning model to sample patient data. The machine learning model determines a respective probability value that indicates a probability that the cardiac arrhythmia occurred during each respective temporal window. The computing system outputs a user interface comprising graphical data based on the sample probability values and receives, via the user interface, an indication of user input to select a probability threshold for a patient. The computing system receives patient data for the patient and applies the machine learning model to the patient data to determine a current probability value. In response to the determination that the current probability exceeds the probability threshold for the patient, the computing system generates an alert indicating the patient has likely experienced the occurrence of the cardiac arrhythmia.
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公开(公告)号：US11443852B2
公开(公告)日：2022-09-13
申请号：US17377763
申请日：2021-07-16
Applicant: Medtronic, Inc.
Inventor： Niranjan Chakravarthy , Siddharth Dani , Tarek D. Haddad , Donald R. Musgrove , Andrew Radtke , Rodolphe Katra , Lindsay A. Pedalty
IPC: G16H50/20 , A61B5/00 , A61B5/11 , G16H50/30 , G06N20/00 , G06N5/04 , G06N5/02 , A61B5/35 , A61B5/316
Abstract: Techniques are disclosed for using feature delineation to reduce the impact of machine learning cardiac arrythmia detection on power consumption of medical devices. In one example, a medical device performs feature-based delineation of cardiac electrogram data sensed from a patient to obtain cardiac features indicative of an episode of arrythmia in the patient. The medical device determines whether the cardiac features satisfy threshold criteria for application of a machine learning model for verifying the feature-based delineation of the cardiac electrogram data. In response to determining that the cardiac features satisfy the threshold criteria, the medical device applies the machine learning model to the sensed cardiac electrogram data to verify that the episode of arrhythmia has occurred or determine a classification of the episode of arrythmia.
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19.发明申请THERAPY PROGRAM SELECTION FOR ELECTRICAL STIMULATION THERAPY BASED ON A VOLUME OF TISSUE ACTIVATION 审中-公开基于组织活动量的电刺激治疗的治疗方案选择公开(公告)号：US20160067495A1
公开(公告)日：2016-03-10
申请号：US14481379
申请日：2014-09-09
Applicant: Medtronic, Inc.
Inventor： Ashutosh Chaturvedi , Siddharth Dani , Timothy J. Denison , William F. Kaemmerer , Shahram Malekkhosravi , Eric J. Panken , Brandon Zingsheim
Abstract: In some examples, a processor of a system evaluates a therapy program based on a score determined based on a volume of tissue expected to be activated (“VTA”) by therapy delivery according to the therapy program. The score may be determined using an efficacy map comprising a plurality of voxels that are each assigned a value. In some examples, the efficacy map is selected from a plurality of stored efficacy maps based on a patient condition, one or more patient symptoms, or both the patient condition and one or more patient symptoms. In addition, in some examples, voxels of the efficacy map are assigned respective values that are associated with a clinical rating scale.
Abstract translation: 在一些示例中，系统的处理器基于通过根据治疗程序的治疗递送基于预期被激活的组织体积（“VTA”）确定的评分来评估治疗程序。 可以使用包括多个体素的功效图来确定分数，每个体素分配一个值。 在一些示例中，基于患者状况，一个或多个患者症状或患者状况和一个或多个患者症状，从多个存储的效能图中选择功效图。 此外，在一些示例中，功效图的体素被分配与临床评级量表相关联的各自的值。
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公开(公告)号：US12161487B2
公开(公告)日：2024-12-10
申请号：US18304696
申请日：2023-04-21
Applicant: Medtronic, Inc.
Inventor： Niranjan Chakravarthy , Siddharth Dani , Tarek D. Haddad , Rodolphe Katra , Donald R. Musgrove , Lindsay A. Pedalty , Andrew Radtke
Abstract: Techniques are disclosed for monitoring a patient for the occurrence of cardiac arrhythmias. A computing system obtains a cardiac electrogram (EGM) strip for a current patient. Additionally, the computing system may apply a first cardiac rhythm classifier (CRC) with a segment of the cardiac EGM strip as input. The first CRC is trained on training cardiac EGM strips from a first population. The first CRC generates first data regarding an aspect of a cardiac rhythm of the current patient. The computing system may also apply a second CRC with the segment of the cardiac EGM strip as input. The second CRC is trained on training cardiac EGM strips from a smaller, second population. The second CRC generates second data regarding the aspect of the cardiac rhythm of the current patient. The computing system may generate output data based on the first and/or second data.
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