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1.发明申请公开(公告)号：US20200164212A1
公开(公告)日：2020-05-28
申请号：US16774418
申请日：2020-01-28
申请人： Medtronic, Inc.
发明人： Ashutosh Chaturvedi , Siddharth Dani , Timothy J. Denison , William F. Kaemmerer , Shahram Malekkhosravi , Eric J. Panken , Brandon Zingsheim
IPC分类号： A61N1/36 , G16H50/50 , A61B5/00 , A61B5/0478 , A61N1/372
摘要： In some examples, a processor of a system evaluates a therapy program based on a score determined based on a volume of tissue expected to be activated (“VTA”) by therapy delivery according to the therapy program. The score may be determined using an efficacy map comprising a plurality of voxels that are each assigned a value. In some examples, the efficacy map is selected from a plurality of stored efficacy maps based on a patient condition, one or more patient symptoms, or both the patient condition and one or more patient symptoms. In addition, in some examples, voxels of the efficacy map are assigned respective values that are associated with a clinical rating scale.
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公开(公告)号：US20190038902A1
公开(公告)日：2019-02-07
申请号：US15666986
申请日：2017-08-02
申请人： Medtronic, Inc.
发明人： William F. Kaemmerer , Duane L. Bourget , Timothy J. Denison , Eric J. Panken , Scott R. Stanslaski
摘要： A medical device may receive sensor data from sensing sources, and determine confidence levels for sensor data received from each of the plurality of sensing sources. Each of the confidence levels of the sensor data from each of the sensing sources is a measure of accuracy of the sensor data received from respective sensing sources. The medical device may also determine one or more therapy parameter values based on the determined confidence levels, and cause delivery of therapy based on the determined one or more therapy parameter values.
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公开(公告)号：US09861821B2
公开(公告)日：2018-01-09
申请号：US15259865
申请日：2016-09-08
申请人： Medtronic, Inc.
发明人： William F. Kaemmerer
CPC分类号： A61N1/36139 , A61N1/36142 , A61N1/37247
摘要： A therapeutic window for at least one electrode of a medical system may be determined based on a volume of tissue expected to be activated (“VTA”) by electrical stimulation delivered by the at least one electrode. In some examples, a processor determines the therapeutic window for a particular electrode by at least determining an efficacy threshold based on the VTA expected to result from the delivery of electrical stimulation according to a set of electrical stimulation parameter values including the stimulation parameter at the efficacy threshold, and determining an adverse-effects threshold based on the VTA expected to result from the delivery of electrical stimulation according to a set of electrical stimulation parameter values including the stimulation parameter at the adverse-effects threshold.
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公开(公告)号：US12036414B2
公开(公告)日：2024-07-16
申请号：US15342167
申请日：2016-11-03
申请人： Medtronic, Inc.
CPC分类号： A61N1/36185 , A61N1/0534 , A61N1/36064 , A61N1/36067 , A61N1/36075 , A61N1/36096 , A61N1/36139 , A61N1/37247 , A61N1/37235
摘要： In one example, a method includes selecting, by one or more processors and based on a representation of sensed electrical signals for a particular patient and a plurality of representations of sensed electrical signals for a plurality of other patients, a combination of electrodes of a plurality of combinations of one or more implantable electrodes for delivery of electrical stimulation to the particular patient.
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5.发明申请THERAPY PROGRAM SELECTION FOR ELECTRICAL STIMULATION THERAPY BASED ON A VOLUME OF TISSUE ACTIVATION 审中-公开基于组织活动量的电刺激治疗的治疗方案选择公开(公告)号：US20160067495A1
公开(公告)日：2016-03-10
申请号：US14481379
申请日：2014-09-09
申请人： Medtronic, Inc.
发明人： Ashutosh Chaturvedi , Siddharth Dani , Timothy J. Denison , William F. Kaemmerer , Shahram Malekkhosravi , Eric J. Panken , Brandon Zingsheim
摘要： In some examples, a processor of a system evaluates a therapy program based on a score determined based on a volume of tissue expected to be activated (“VTA”) by therapy delivery according to the therapy program. The score may be determined using an efficacy map comprising a plurality of voxels that are each assigned a value. In some examples, the efficacy map is selected from a plurality of stored efficacy maps based on a patient condition, one or more patient symptoms, or both the patient condition and one or more patient symptoms. In addition, in some examples, voxels of the efficacy map are assigned respective values that are associated with a clinical rating scale.
摘要翻译： 在一些示例中，系统的处理器基于通过根据治疗程序的治疗递送基于预期被激活的组织体积（“VTA”）确定的评分来评估治疗程序。 可以使用包括多个体素的功效图来确定分数，每个体素分配一个值。 在一些示例中，基于患者状况，一个或多个患者症状或患者状况和一个或多个患者症状，从多个存储的效能图中选择功效图。 此外，在一些示例中，功效图的体素被分配与临床评级量表相关联的各自的值。
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公开(公告)号：US10799700B2
公开(公告)日：2020-10-13
申请号：US15666986
申请日：2017-08-02
申请人： Medtronic, Inc.
发明人： William F. Kaemmerer , Duane L. Bourget , Timothy J. Denison , Eric J. Panken , Scott R. Stanslaski
IPC分类号： A61B5/0482 , A61N1/36 , A61N1/05 , A61N1/372
摘要： A medical device may receive sensor data from sensing sources, and determine confidence levels for sensor data received from each of the plurality of sensing sources. Each of the confidence levels of the sensor data from each of the sensing sources is a measure of accuracy of the sensor data received from respective sensing sources. The medical device may also determine one or more therapy parameter values based on the determined confidence levels, and cause delivery of therapy based on the determined one or more therapy parameter values.
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7.发明授权公开(公告)号：US10583293B2
公开(公告)日：2020-03-10
申请号：US14481379
申请日：2014-09-09
申请人： Medtronic, Inc.
发明人： Ashutosh Chaturvedi , Siddharth Dani , Timothy J. Denison , William F. Kaemmerer , Shahram Malekkhosravi , Eric J. Panken , Brandon Zingsheim
摘要： In some examples, a processor of a system evaluates a therapy program based on a score determined based on a volume of tissue expected to be activated (“VTA”) by therapy delivery according to the therapy program. The score may be determined using an efficacy map comprising a plurality of voxels that are each assigned a value. In some examples, the efficacy map is selected from a plurality of stored efficacy maps based on a patient condition, one or more patient symptoms, or both the patient condition and one or more patient symptoms. In addition, in some examples, voxels of the efficacy map are assigned respective values that are associated with a clinical rating scale.
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8.发明申请公开(公告)号：US20190111266A1
公开(公告)日：2019-04-18
申请号：US16228972
申请日：2018-12-21
申请人： Medtronic, Inc.
摘要： In some examples, a processor of a system evaluates a therapy program based on a score determined based on a volume of tissue expected to be activated (“VTA”) by therapy delivery according to the therapy program. The score may be determined using a three-dimensional (3D) grid comprising a plurality of voxels that are each assigned a value. The processor may register the VTA with the 3D grid and determine the score for the therapy program based on the values assigned to voxels with which the VTA overlaps. One or more therapy programs for electrical stimulation therapy (e.g., deep brain stimulation) may be selected based on the scores determined based on the 3D grid.
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9.发明申请THERAPY PROGRAM SELECTION FOR ELECTRICAL STIMULATION THERAPY BASED ON A VOLUME OF TISSUE ACTIVATION 审中-公开基于组织活动量的电刺激治疗的治疗方案选择公开(公告)号：US20160250476A1
公开(公告)日：2016-09-01
申请号：US15044795
申请日：2016-02-16
申请人： Medtronic, Inc.
CPC分类号： A61N1/36135 , A61N1/3605 , A61N1/36082 , A61N1/36128 , A61N1/36182 , A61N1/36185 , A61N1/37247 , G06F19/00 , G06F19/3481 , G16H50/30 , G16H50/50
摘要： In some examples, a processor of a system evaluates a therapy program based on a score determined based on a volume of tissue expected to be activated (“VTA”) by therapy delivery according to the therapy program. The score may be determined using a three-dimensional (3D) grid comprising a plurality of voxels that are each assigned a value. The processor may register the VTA with the 3D grid and determine the score for the therapy program based on the values assigned to voxels with which the VTA overlaps. One or more therapy programs for electrical stimulation therapy (e.g., deep brain stimulation) may be selected based on the scores determined based on the 3D grid.
摘要翻译： 在一些示例中，系统的处理器基于通过根据治疗程序的治疗递送基于预期被激活的组织体积（“VTA”）确定的评分来评估治疗程序。 可以使用包括多个体素的三维（3D）网格来确定分数，每个体素分配一个值。 处理器可以使用3D网格注册VTA，并且基于分配给与VTA重叠的体素的值来确定治疗程序的得分。 可以基于基于3D网格确定的评分来选择用于电刺激治疗（例如，深脑刺激）的一个或多个治疗程序。
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公开(公告)号：US20150246233A1
公开(公告)日：2015-09-03
申请号：US14195489
申请日：2014-03-03
申请人： Medtronic, Inc.
发明人： William F. Kaemmerer
CPC分类号： A61N1/36139 , A61N1/36142 , A61N1/37247
摘要： A therapeutic window for at least one electrode of a medical system may be determined based on a volume of tissue expected to be activated (“VTA”) by electrical stimulation delivered by the at least one electrode. In some examples, a processor determines the therapeutic window for a particular electrode by at least determining an efficacy threshold based on the VTA expected to result from the delivery of electrical stimulation according to a set of electrical stimulation parameter values including the stimulation parameter at the efficacy threshold, and determining an adverse-effects threshold based on the VTA expected to result from the delivery of electrical stimulation according to a set of electrical stimulation parameter values including the stimulation parameter at the adverse-effects threshold.
摘要翻译： 医疗系统的至少一个电极的治疗窗口可以基于由至少一个电极传递的电刺激预期被激活的组织的体积（“VTA”）来确定。 在一些示例中，处理器通过至少基于预期由电刺激输送产生的VTA来确定特定电极的治疗窗口，所述VTA根据包括效力的刺激参数的一组电刺激参数值 阈值，并且根据包括在不利影响阈值处的刺激参数的一组电刺激参数值，基于预期由电刺激递送而产生的VTA确定不利影响阈值。
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