公开(公告)号：US10349872B2

公开(公告)日：2019-07-16

申请号：US14980260

申请日：2015-12-28

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Andrea Varsavsky ,  Yunfeng Lu ,  Jay Mung

IPC: A61B5/00 ,  A61B5/1495 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/053

Abstract: A single, optimal, fused sensor glucose value may be calculated based on respective sensor glucose values of a plurality of redundant working electrodes (WEs) of a glucose sensor. Respective electrochemical impedance spectroscopy (EIS) procedures may be performed for each of the WEs to obtain values of membrane resistance (Rmem) for each WE. A noise value and a calibration factor (CF) value may be calculated for each WE, and respective fusion weights may be calculated for Rmem, noise, and CF for each WE. An overall fusion weight may then be calculated based on the WE's Rmem fusion weight, noise fusion weight, and CF fusion weight, such that a single, optimal, fused sensor glucose value may be calculated based on the respective overall fusion weight and sensor glucose value of each of the plurality of redundant working electrodes.

公开(公告)号：US20200000381A1

公开(公告)日：2020-01-02

申请号：US16023943

申请日：2018-06-29

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Yunfeng Lu ,  Andrea Varsavsky

IPC: A61B5/1495 ,  A61B5/1486 ,  A61B5/145 ,  A61B90/00

Abstract: Vset-based systems and methods for performing sensor health diagnostics are disclosed. Methods and systems for in-body glucose sensor health diagnostics may use steady-state Isig characterization under full-range operating Vsets, transient Isig response characterization after Vset alternations, transient Vset characterization, and open circuit potential measurements for estimating sensor health and for monitoring sensor properties.

公开(公告)号：US20190274604A1

公开(公告)日：2019-09-12

申请号：US16426750

申请日：2019-05-30

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Andrea Varsavsky ,  Yunfeng Lu ,  Jay Mung

IPC: A61B5/145 ,  A61B5/053 ,  A61B5/00 ,  A61B5/1495 ,  A61B5/1486

Abstract: A single, optimal, fused sensor glucose value may be calculated based on respective sensor glucose values of a plurality of redundant working electrodes (WEs) of a glucose sensor. Respective electrochemical impedance spectroscopy (EIS) procedures may be performed for each of the WEs to obtain values of membrane resistance (Rmem) for each WE. A noise value and a calibration factor (CF) value may be calculated for each WE, and respective fusion weights may be calculated for Rmem, noise, and CF for each WE. An overall fusion weight may then be calculated based on the WE's Rmem fusion weight, noise fusion weight, and CF fusion weight, such that a single, optimal, fused sensor glucose value may be calculated based on the respective overall fusion weight and sensor glucose value of each of the plurality of redundant working electrodes.

公开(公告)号：US20170181671A1

公开(公告)日：2017-06-29

申请号：US14980114

申请日：2015-12-28

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Andrea Varsavsky ,  Jay Mung ,  Yunfeng Lu ,  Mohammad Mehdi Korjani

IPC: A61B5/1495 ,  A61B5/053 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1473

CPC classification number: A61B5/1495 ,  A61B5/053 ,  A61B5/0537 ,  A61B5/14532 ,  A61B5/1473 ,  A61B5/7203 ,  A61B5/7225

Abstract: An unscented Kalman filter is used to enable sensor calibration independently of the actual design of the subject sensors. By utilizing an unscented Kalman filter, an underlying calibration methodology is developed that is sensor-unspecific, such that a single calibration methodology and related systems may be used to calibrate various sensors, without the need to re-calculate a calibration factor for each specific sensor, and without the need to design a separate filtering mechanism to compensate for noise. In this way, various calibration inputs can be allowed to change over time without the need to change the codebase on which the calibration methodology otherwise operates. In multi-electrode systems, the methodology may incorporate a fusion algorithm to provide a single, fused sensor glucose value. The fusion algorithm may incorporate, and/or work in conjunction with, Electrochemical Impedance Spectroscopy (EIS) procedures.

公开(公告)号：US20170049964A1

公开(公告)日：2017-02-23

申请号：US15240733

申请日：2016-08-18

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Andrea Varsavsky ,  Yunfeng Lu ,  Keith Nogueira ,  Jeffrey Nishida

IPC: A61M5/172 ,  G06F19/00 ,  A61B5/024 ,  A61B5/00 ,  A61B5/145

Abstract: Medical devices and related patient management systems and parameter modeling methods are provided. An exemplary method involves obtaining, by a computing device, historical measurements of a condition in a body of the patient previously provided by a sensing device, obtaining, by the computing device, historical operational context information associated with preceding operation of one or more of an infusion device and the sensing device, obtaining, by the computing device, historical values for a parameter from one or more of the infusion device and the sensing device, determining, by the computing device a patient-specific model of the parameter based on relationships between the historical measurements, the historical operational context information and the historical values, and providing, by the computing device via a network, the patient-specific model to one of the infusion device, the sensing device or a client device.

Abstract translation: 提供了医疗设备和相关的患者管理系统和参数建模方法。 一种示例性方法包括由计算设备获得先前由感测设备提供的患者体内的状况的历史测量，由计算设备获得与先前操作中的一个或多个相关联的历史操作上下文信息 输注装置和感测装置，由计算装置获得来自一个或多个输注装置和感测装置的参数的历史值，由计算装置根据患者特定的参数模型，根据 历史测量，历史操作上下文信息和历史值，并且由计算设备经由网络将患者特定模型提供给输注设备，感测设备或客户端设备之一。