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    Cell-Targeted IKB and Methods for the Use Thereof
    12.
    发明申请
    Cell-Targeted IKB and Methods for the Use Thereof 审中-公开
    细胞靶向的IKB及其​​使用方法

    公开(公告)号：US20070202593A1

    公开(公告)日：2007-08-30

    申请号：US11679630

    申请日：2007-02-27

    申请人： Yuying Liu ,  Michael Rosenblum

    发明人： Yuying Liu ,  Michael Rosenblum

    IPC分类号： C12N7/00 ,  C12N5/00 ,  C12N7/01 ,  C12N5/02

    CPC分类号： C07K16/30 ,  A61K47/6813 ,  A61K47/6851 ,  A61K47/6865 ,  A61K2039/505 ,  C07K14/4702 ,  C07K16/3053 ,  C07K16/32 ,  C07K2317/622 ,  C07K2317/76 ,  C07K2317/77 ,  C07K2319/00 ,  C07K2319/33

    摘要： Activation of nuclear factor kB (NF-kB) is involved in a number of diseases such as viral and bacterial infections, and cell proliferative disorders such as cancer and autoimmune disease. In certain instances, constitutive NF-kB activity has also been liked to the resistance of certain cancers to chemo and radiation therapy. The instant invention concerns method of inhibiting NF-kB activity in target cell populations by deliver of a polypeptide inhibitor of NF-kB (IkB). Methods of the invention may be used to treat diseases such as infections, and cell proliferative disorders. Methods for sensitizing cells to apoptosis and cytotoxic therapies are also described.

    摘要翻译： 核因子kB（NF-kB）的激活涉及许多疾病如病毒和细菌感染以及细胞增殖性疾病如癌症和自身免疫性疾病。 在某些情况下，组成型NF-kB活性也被喜欢某些癌症对化疗和放射治疗的抵抗力。 本发明涉及通过递送NF-kB（IkB）的多肽抑制剂来抑制靶细胞群体中的NF-kB活性的方法。 本发明的方法可用于治疗疾病如感染和细胞增殖性疾病。 还描述了使细胞对细胞凋亡和细胞毒性疗法敏感的方法。

    Candle warmer lamp
    13.
    外观设计
    Candle warmer lamp 有权

    公开(公告)号：USD1038487S1

    公开(公告)日：2024-08-06

    申请号：US29925350

    申请日：2024-01-24

    申请人： Yuying Liu

    设计人： Yuying Liu

    摘要： FIG. 1 is a perspective view of a candle warmer lamp showing my new design;
    FIG. 2 is another perspective view thereof;
    FIG. 3 is a front elevational view thereof;
    FIG. 4 is a rear elevational view thereof;
    FIG. 5 is a left side elevational view thereof;
    FIG. 6 is a right side elevational view thereof;
    FIG. 7 is a top plan view thereof;
    FIG. 8 is a bottom plan view thereof; and,
    FIG. 9 is an enlarged view of portion 9 shown in FIG. 2.
    The broken lines in the drawings depict portions of the candle warmer lamp that form no part of the claimed design.
    The dot-dash broken lines represent boundaries of the enlarged portions and form no part of the claimed design.