公开(公告)号：US07637260B2

公开(公告)日：2009-12-29

申请号：US10276531

申请日：2001-06-08

Applicant: Michael Holroyd

Inventor： Michael Holroyd

IPC: A61M11/00

CPC classification number: A61M15/0091 ,  A61M15/009 ,  A61M15/0093 ,  A61M15/0096 ,  Y10T156/10

Abstract: A metered dose inhaler for use with a pressurized aerosol container which is preferably breath-actuated. A preload is applied to the internal aerosol valve by an amount sufficient to result in a dose release, but this is prevented by the application of a pneumatic resisting force. The inhaler comprises a release device which, upon actuation, releases the resisting force and allows the preload to actuate the aerosol valve. A metered dose of medicament is then released for inhalation by the patient. The pneumatic resisting force is established by a negative pressure region defined in part by a diaphragm. The diaphragm includes a central disk of a first, relatively high stiffness material and a peripheral ring, coupled by a flexure of a second, relatively low stiffness material.

Abstract translation: 一种用于与优选呼吸致动的加压气溶胶容器一起使用的计量吸入器。 对内部喷雾阀施加足以导致剂量释放的量的预加载，但是这通过施加气动阻力来防止。 吸入器包括释放装置，其在致动时释放抵抗力并允许预压力致动气溶胶阀。 然后释放计量剂量的药物以供患者吸入。 通过由隔膜部分限定的负压区域来建立气动阻力。 隔膜包括通过第二相对低刚度材料的挠曲而联接的第一相对高刚度材料的中心盘和外围环。