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公开(公告)号：US12128180B2
公开(公告)日：2024-10-29
申请号：US17496665
申请日：2021-10-07
申请人： JUUL Labs, Inc.
IPC分类号： A24F13/00 , A24B15/167 , A24D3/17 , A24F3/02 , A24F7/04 , A24F40/46 , A24F40/48 , A24F40/485 , A24F40/50 , A24F40/85 , A61M11/00 , A61M11/04 , A61M11/08 , A61M15/00 , A61M15/06 , A61M16/00 , F16K15/18 , F16K31/00 , H05B1/02 , A24F40/10
CPC分类号： A61M15/06 , A24B15/167 , A24D3/17 , A24F3/02 , A24F7/04 , A24F40/46 , A24F40/48 , A24F40/485 , A24F40/50 , A24F40/85 , A61M11/003 , A61M11/007 , A61M11/042 , A61M11/08 , A61M15/0093 , A61M16/0003 , F16K15/1825 , F16K31/002 , H05B1/0227 , H05B1/0297 , A24F40/10 , A61M2016/0024 , A61M2205/075 , A61M2205/13 , A61M2205/3334 , A61M2205/3368 , A61M2205/3653 , A61M2205/502 , A61M2205/7536 , A61M2206/20
摘要： Deformable valves and atomizer designs for a vaporizer (e.g., electronic cigarette). The vaporizer may be used for vaporization of liquid and/or organic material. The vaporizer may enable enhanced flow control of fluid and may generate high quality and quantity of vapor efficiently. In some instances, flow path of the vaporizer may allow bulk fluid flow, e.g., in contrast to capillary flow, to deliver fluid to a vicinity of the vaporizer. In some instances, the vaporizer may utilize improved atomizer designs for vaporizing devices, where said designs can be configured optionally, with various embodiments of a breath-modulating deformable valve.
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公开(公告)号：US11679212B2
公开(公告)日：2023-06-20
申请号：US16101617
申请日：2018-08-13
发明人： Marcus Knell , Michael Aven , Benjamin Franzmann , Steffen Schuy , Herbert Wachtel , Guido Endert , Alexander Christ , Horst Wergen
CPC分类号： A61M15/08 , A61D7/04 , A61M15/009 , A61M15/0013 , A61M15/0073 , A61M15/0086 , A61M15/0093 , A61M15/0096 , B05B11/1056 , A61M15/0018 , A61M2205/581 , A61M2205/583 , A61M2250/00 , B05B7/0012 , B05B11/0038 , B05B11/1091
摘要： An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with a pressure generator, which has a tensioning device for the drive, and with a tensioning mechanism for tensioning the tensioning device, whereby the tensioning mechanism has a lever gear for tensioning the tensioning device.
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公开(公告)号：US09969544B2
公开(公告)日：2018-05-15
申请号：US14780486
申请日：2014-03-25
IPC分类号： B65D83/14 , B65D83/42 , B65D83/48 , A61M15/00 , A24F47/00 , A24B15/16 , B65B3/14 , B65B31/04 , A61M15/06
CPC分类号： B65D83/752 , A24B15/16 , A24F47/002 , A24F47/006 , A61M15/0093 , A61M15/06 , A61M2202/0468 , A61M2209/045 , B65B3/14 , B65B31/047 , B65D83/42 , B65D83/48 , A61M2202/0007
摘要： A pressurized refill canister containing a composition including a propellant. The canister has an outlet valve having a stem biased to a closed position by a first resilient member. The stem has a maximum outer diameter of greater than 3 mm. At the outlet end of the stem, at least part of the wall of the stem extends inwardly from the outside diameter for at least 50% of the radius.
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公开(公告)号：US09918961B2
公开(公告)日：2018-03-20
申请号：US14622205
申请日：2015-02-13
发明人： Alex Hearn , Ritika Gupta , Moira Bowdrey
CPC分类号： A61K31/352 , A61K9/008 , A61K31/05 , A61K47/10 , A61M11/02 , A61M15/0093 , A61M15/06 , A61M2202/0468 , A61M2202/0007
摘要： The present invention provides a cannabinoid inhaler, compositions, and methods for delivering a cannabinoid composition to a subject. The cannabinoid composition is delivered in the form of inhaled droplets of respirable size via pulmonary administration. The invention may be used in the treatment of a condition or disorder selected from the group consisting of neuropathic pain, cannabis addiction, nausea, motion sickness, arthritis, and neurodegenerative disease.
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公开(公告)号：US09913952B2
公开(公告)日：2018-03-13
申请号：US14462867
申请日：2014-08-19
发明人： Marcus Knell , Guido Endert , Horst Wergen
CPC分类号： A61M15/08 , A61D7/04 , A61M11/006 , A61M15/0013 , A61M15/0018 , A61M15/0073 , A61M15/0086 , A61M15/009 , A61M15/0093 , A61M15/0096 , A61M2205/581 , A61M2205/583 , A61M2250/00
摘要： This invention relates to an inhaler with a respiration indicator, whereby the inhaler has a chamber wall forming a chamber and a dispensing device for fluidic connection of the chamber to a bodily opening, preferably a nostril, whereby the respiration indicator has a wall section of the chamber wall or is formed in this way, whereby the wall section is designed to indicate a respiratory activity by deformation and/or movement.
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公开(公告)号：US20180043585A9
公开(公告)日：2018-02-15
申请号：US15022589
申请日：2014-09-19
CPC分类号： B29C43/003 , A61F2/2412 , A61F2/2415 , A61K9/0075 , A61K9/0078 , A61K9/12 , A61L27/367 , A61L27/3687 , A61L27/3691 , A61L27/50 , A61L2400/18 , A61L2430/20 , A61L2430/40 , A61M15/0093 , A61M2202/064 , B29C35/0261 , B29L2031/753
摘要： A method of delivering a therapeutic agent comprises providing an aerosol generator that produces an aerosol of particles or droplets containing a therapeutic agent and an excipient for delivery to a first portion of a respiratory tract. The particles or droplets have an initial diameter from about 1 μm to about 8 μm, and the initial momentum of the particles or droplets minimizes deposition in the first portion. The particles or droplets are exposed to relative humidity in the respiratory tract by delivering them at a flow rate that defines the residence time in the respiratory tract. The particles or droplets increase in diameter due to hygroscopic growth caused by relative humidity. The aerosol is nasally exhaled so that particles or droplets are delivered to the nasal cavity and deposited in the nasal turbinates or sinus in part because of their increased diameter.
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公开(公告)号：US20170368273A1
公开(公告)日：2017-12-28
申请号：US15672021
申请日：2017-08-08
申请人： DARREN RUBIN
发明人： DARREN RUBIN
CPC分类号： A61M11/042 , A24F47/008 , A61M11/005 , A61M11/007 , A61M11/041 , A61M11/047 , A61M11/06 , A61M15/0008 , A61M15/002 , A61M15/0028 , A61M15/0066 , A61M15/008 , A61M15/0085 , A61M15/0091 , A61M15/0093 , A61M15/0095 , A61M15/02 , A61M15/025 , A61M15/06 , A61M16/0093 , A61M16/0866 , A61M16/101 , A61M16/105 , A61M16/1055 , A61M16/1065 , A61M16/14 , A61M16/204 , A61M16/209 , A61M2016/0027 , A61M2016/0033 , A61M2016/0039 , A61M2202/064 , A61M2202/30 , A61M2205/13 , A61M2205/3653 , A61M2205/505 , A61M2205/52 , A61M2205/6018 , A61M2205/6054 , A61M2205/6072 , A61M2205/8206 , A61M2205/8237 , A61M2205/8262 , A61M2205/8268 , A61M2210/0618 , A61M2210/065 , A61M2210/1028 , A61M2210/1032 , A61M2210/1035 , A61M2210/1039
摘要： Systems and methods are provided for aerosolizing and delivering therapeutic substances in an electronic aerosol delivery device with airflow regulation. Calibrated airflow resistance settings enable adjustment and control of flow velocity and or flow volume of air, aerosolized air, and or entrained aerosol particles, through the device, for optimal aerosol delivery among diverse conditions and applications.
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公开(公告)号：US20160368181A1
公开(公告)日：2016-12-22
申请号：US15022589
申请日：2014-09-19
CPC分类号： B29C43/003 , A61F2/2412 , A61F2/2415 , A61K9/0075 , A61K9/0078 , A61K9/12 , A61L27/367 , A61L27/3687 , A61L27/3691 , A61L27/50 , A61L2400/18 , A61L2430/20 , A61L2430/40 , A61M15/0093 , A61M2202/064 , B29C35/0261 , B29L2031/753
摘要： An assembly and methods for providing a contoured biological tissue are described. The assembly comprises a first plate and a second plate. The first plate is configured to receive a biological tissue. The second plate is configured to apply a compressive force on the biological tissue that is disposed on the first plate. One or both of the first and second plates comprise a defined shape and a contoured area within the defined shape. The contoured area comprises at least first and second elevations and a continuous transition between the first and second transitions. One or more energy sources is associated with one or both of the first and second plates. The one or more energy sources delivers energy while the second plate applies the compressive force on the biological tissue disposed on the first plate.
摘要翻译： 描述了用于提供轮廓生物组织的组件和方法。 组件包括第一板和第二板。 第一板被配置成接收生物组织。 第二板构造成对设置在第一板上的生物组织施加压缩力。 第一和第二板中的一个或两个包括限定形状和限定形状内的轮廓区域。 轮廓区域包括至少第一和第二高程以及第一和第二过渡之间的连续过渡。 一个或多个能源与第一和第二板中的一个或两个相关联。 一个或多个能量源传递能量，而第二板将压缩力施加在设置在第一板上的生物组织上。
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公开(公告)号：US09408987B2
公开(公告)日：2016-08-09
申请号：US13389434
申请日：2010-08-06
申请人： Alex Hearn , Iain McDerment
发明人： Alex Hearn , Iain McDerment
CPC分类号： A61M15/0093 , A24F47/002 , A61M15/0091 , A61M15/06 , A61M16/20 , A61M2205/8225
摘要： An inhaler comprising a reservoir of an inhalable composition with an outlet at one end through which the inhalable composition is discharged. A non-metered breath-activated valve is provided between the one end and the reservoir, the breath-activated valve comprising a flow path extending from the reservoir to the outlet end. At least a portion of the flow path is a deformable tube. A clamping member pinches the deformable tube closed when no suction force is applied to the device and releases the tube to open the flow path when suction is applied at the outlet, to provide uninterrupted flow from the reservoir to the outlet.
摘要翻译： 一种吸入器，其包括可吸入组合物的储存器，其一端具有可吸入组合物排出的出口。 在一端和储存器之间设置非计量呼吸激活阀，该呼吸激活阀包括从贮存器延伸到出口端的流路。 流路的至少一部分是可变形管。 当在出口处施加抽吸时，夹紧构件将可变形管夹紧，当没有抽吸力施加到装置时释放管以打开流动路径，从而提供从储存器到出口的不间断的流动。
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10.发明申请公开(公告)号：US20160129205A1
公开(公告)日：2016-05-12
申请号：US14733143
申请日：2015-06-08
申请人： SIPNOSE LTD.
发明人： Daniel SHAHAF , Iris SHICHOR
IPC分类号： A61M11/02
CPC分类号： A61M11/02 , A61M11/001 , A61M15/0003 , A61M15/003 , A61M15/0061 , A61M15/0065 , A61M15/0091 , A61M15/0093 , A61M15/08 , A61M31/00 , A61M2202/04 , A61M2202/064 , A61M2205/073 , A61M2205/7509 , A61M2205/7518 , A61M2205/7545 , A61M2206/16 , A61M2209/02 , A61M2210/0618 , A61M2210/0625 , A61M2210/065 , A61M2210/0662 , A61M2210/1089 , A61M2210/1475 , B05B1/002
摘要： A device for delivering a predetermined volume a substance within a body cavity. The device includes: at least one predefined volume sized and shaped to contain a predetermined volume the substance; a delivery end in fluid communication with a container; and at least one valve mechanically connected to the container and configurable between an active configuration in which the valve enables delivery of a volume of the substance and an inactive configuration, in which the valve prevents delivery.
摘要翻译： 一种用于在体腔内输送物质的预定体积的装置。 该装置包括：至少一个预定体积的大小和形状以容纳预定体积的物质; 与容器流体连通的输送端; 以及至少一个机械地连接到所述容器并且可在活动构型之间配置的阀，其中所述阀能够输送所述物质的体积和非活动构型，其中所述阀阻止递送。
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