B RING REDUCED-D RING OXIDIZED TETRAPYROLLIC PHOTOSENSITIZERS FOR PHOTODYNAMIC THERAPY AND TUMOR IMAGING
    11.
    发明申请
    B RING REDUCED-D RING OXIDIZED TETRAPYROLLIC PHOTOSENSITIZERS FOR PHOTODYNAMIC THERAPY AND TUMOR IMAGING 有权
    用于光化学治疗和肿瘤成像的B环减少D环氧化的光致变色光敏剂

    公开(公告)号:US20110264027A1

    公开(公告)日:2011-10-27

    申请号:US12918238

    申请日:2009-02-19

    CPC分类号: C07D487/22

    摘要: Tetrapyrollic photosensitizers and imaging agent compounds having A, B, C, and D rings and having a reduced B ring and an oxidized D ring. The compounds preferably have a purity of at least 95 percent and preferably have a fused system connected at an unsaturated carbon atom of the C ring nearest the D ring and at the unsaturated carbon atom between the C and D rings. The invention also includes a method of making the compounds at over 95 percent yield by starting with a B and D ring oxidized tetrapyrollic compound and dissolving it in a halogenated hydrocarbon solvent and treating it with sufficient nitroalkane solution of FeCl3.6H2O to oxidize the D ring and separating the resulting organic layer and drying.

    摘要翻译: 具有A,B,C和D环并且具有还原的B环和氧化的D环的四味光敏剂和显影剂化合物。 化合物优选具有至少95%的纯度,并且优选具有在C环的最接近D环的不饱和碳原子和C和D环之间的不饱和碳原子连接的稠合体系。 本发明还包括一种通过用B和D环氧化的四羰基化合物开始制备化合物超过95%的方法,并将其溶解在卤代烃溶剂中并用足量的FeCl 3·6H 2 O的硝基烷烃溶液处理以氧化D环 并分离得到的有机层并干燥。

    DYNAMIC CREATION OF MAIL ALIASES USABLE IN ELECTRONIC COMMUNICATIONS
    12.
    发明申请
    DYNAMIC CREATION OF MAIL ALIASES USABLE IN ELECTRONIC COMMUNICATIONS 失效
    电子通信中可用的邮件动态制作

    公开(公告)号:US20080098069A1

    公开(公告)日:2008-04-24

    申请号:US11550973

    申请日:2006-10-19

    IPC分类号: G06F15/16

    摘要: Mail aliases are dynamically created in response to replies of an electronic mail (e-mail) communication. An e-mail communication is sent to a plurality of recipients, and one or more recipients of the e-mail communication respond to the e-mail. In response to receiving the replies, one or more mail aliases are automatically created.

    摘要翻译: 邮件别名是为响应电子邮件(电子邮件)通信的回复而动态创建的。 电子邮件通信被发送到多个接收者,并且电子邮件通信的一个或多个接收者响应该电子邮件。 响应收到回复,会自动创建一个或多个邮件别名。