公开(公告)号：US4968624A

公开(公告)日：1990-11-06

申请号：US342915

申请日：1989-04-25

申请人： David Bacehowski ,  Arnold Bilstad ,  Michael R. Keilman

发明人： David Bacehowski ,  Arnold Bilstad ,  Michael R. Keilman

IPC分类号： C12M1/00 ,  C12M3/00

CPC分类号： C12M23/14 ,  B65D77/065 ,  B65D81/107 ,  C12M29/06

摘要： The present invention provides a large volume flexible container capable of containing a fluid to be maintained under sterile conditions. The container comprises an inner liner constructed from a polyolefin that defines an interior of the container and an outer liner constructed from a three-layer laminate. The laminate includes an inner layer constructed from a polyolefin that will, upon the application of sufficient energy, bond to the polyolefin of the inner liner, a middle layer constructed from a barrier material, and an outer layer; the inner liner and outer liner being sealed together along edges of the container. At least one tube member, for accessing the container, extends from a face of the container, and includes an end that is secured to the container, a length of flexible tubing for defining a channel through which fluid can flow, and a connector at a second end. A structure for housing the container is also provided.

摘要翻译： 本发明提供一种能够容纳要在无菌条件下保持的流体的大容积柔性容器。 容器包括由限定容器内部的聚烯烃构成的内衬层和由三层层压体构成的外衬垫。 层压体包括由聚烯烃构成的内层，其将在施加足够的能量时粘合到内衬的聚烯烃上，由阻挡材料构成的中间层和外层; 内衬和外衬层沿容器的边缘密封在一起。 用于接近容器的至少一个管构件从容器的表面延伸，并且包括固定到容器的端部，用于限定流体可以流过的通道的一段柔性管道，以及连接器 第二端 还提供了一种用于容纳容器的结构。

公开(公告)号：US4910147A

公开(公告)日：1990-03-20

申请号：US247463

申请日：1988-09-21

申请人： David V. Bacehowski ,  Arnold C. Bilstad ,  David Fisher ,  Robert Gliniecki ,  Michael R. Keilman ,  Sidney T. Smith

发明人： David V. Bacehowski ,  Arnold C. Bilstad ,  David Fisher ,  Robert Gliniecki ,  Michael R. Keilman ,  Sidney T. Smith

IPC分类号： C12M1/00 ,  C12M3/00

CPC分类号： C12M23/14 ,  C12M29/06

摘要： A cell culture media container is provided. The container comprises a body constructed from flexible film and defining a containment area for containing the cell culture media, the body including a front face and a back face, the front and back face being sealed to each other along at least three sides thereof. The container includes a fill port for filling the containment area with cell culture media, the port being sealed to a face of the body and being so constructed and arranged that it extends from the face normal thereto. The container is constructed from a high barrier, optically clear, radiation sterilizable film.

摘要翻译： 提供细胞培养基容器。 容器包括由柔性膜构成的主体并且限定用于容纳细胞培养基的容纳区域，所述容器包括前表面和后表面，所述前表面和后表面沿着其至少三个侧面被彼此密封。 容器包括用于用容纳细胞培养基填充容纳区域的填充口，该孔口被密封到主体的表面，并被构造和布置成使得其从正面与其正面延伸。 容器由高屏障，光学透明的辐射灭菌膜构成。

公开(公告)号：US4568345A

公开(公告)日：1986-02-04

申请号：US534476

申请日：1983-09-21

申请人： Michael R. Keilman ,  Richard L. West

发明人： Michael R. Keilman ,  Richard L. West

IPC分类号： A61J1/00 ,  A61J1/14 ,  A61M5/00

CPC分类号： A61J1/1425 ,  A61J1/1487 ,  A61J1/10 ,  A61J1/1431 ,  A61J1/145 ,  A61J1/1468

摘要： A container for pooling plasma and the like has an integral cap. The cap includes an air vent with an inline bacterial filter. The cap also includes a fluid passage to which a length of tubing is integrally connected. The tubing includes at its unattached end one or more connector members which can be coupled to a fluid source to enable fluid to be transferred into the container via the tubing. The connector members are releasably secured to the cap prior to use. After fluid transfer is complete, the transfer tubing is sealed and severed close to the cap. The cap includes a pocket which receives the remaining sealed end portion of the tubing to protect the sealed end portion from inadvertent contact and damage during subsequent handling. The cover includes a plug which can be moved into a position which hermetically seals the vent and, thus, the entire container.

摘要翻译： 用于汇集等离子体等的容器具有整体盖。 盖子包括带有内联细菌过滤器的通风口。 盖子还包括流体通道，一段长度的管道一体连接到该流体通道。 管道在其未连接的端部包括一个或多个连接器构件，其可以耦合到流体源以使得流体能够经由管道被转移到容器中。 连接器构件在使用之前可释放地固定到盖上。 流体转移完成后，传输管被密封并靠近盖子切断。 盖子包括一个口袋，其容纳管道的剩余的密封端部分，以保护密封的端部部分免于随后的处理期间的意外接触和损坏。 该盖包括可移动到气密地密封通气孔的位置，因此可以移动到整个容器的位置。

公开(公告)号：US4508236A

公开(公告)日：1985-04-02

申请号：US636075

申请日：1984-07-31

申请人： Michael R. Keilman ,  Richard West

发明人： Michael R. Keilman ,  Richard West

IPC分类号： A61J1/00 ,  A61J1/14 ,  B65D51/16

CPC分类号： A61J1/1431 ,  A61J1/1425 ,  A61J1/1487 ,  A61J1/10 ,  A61J1/145 ,  A61J1/1468 ,  Y10T137/86332

摘要： A container for pooling plasma and the like has an integral cap. The cap includes an air vent with an inline bacterial filter. The cap also includes a fluid passage to which a length of tubing can be integrally connected to transfer fluid into the container. The transfer tubing can be sealed and severed close to the cap. The cap includes a pocket which receives the remaining sealed end portion of the tubing to protect the sealed end portion from inadvertent contact and damage during subsequent handling. The cap also includes a cover which closes the pocket to further enhance the protection of the sealed tubing end. The cover includes a plug which, when the pocket is closed, hermetically seals the vent and, thus, the entire container.

摘要翻译： 用于汇集等离子体等的容器具有整体盖。 盖子包括带有内联细菌过滤器的通风口。 盖子还包括流体通道，一段长度的管道可以整体连接到该流体通道，以将流体转移到容器中。 输送管可以密封并靠近盖子切断。 盖子包括一个口袋，其容纳管道的剩余的密封端部分，以保护密封的端部部分免于随后的处理期间的意外接触和损坏。 盖子还包括封闭口袋以进一步增强密封管端的保护的盖子。 盖子包括塞子，当口袋关闭时，该密封件气密地密封通风口，从而密封整个容器。