公开(公告)号：US4910147A

公开(公告)日：1990-03-20

申请号：US247463

申请日：1988-09-21

申请人： David V. Bacehowski ,  Arnold C. Bilstad ,  David Fisher ,  Robert Gliniecki ,  Michael R. Keilman ,  Sidney T. Smith

发明人： David V. Bacehowski ,  Arnold C. Bilstad ,  David Fisher ,  Robert Gliniecki ,  Michael R. Keilman ,  Sidney T. Smith

IPC分类号： C12M1/00 ,  C12M3/00

CPC分类号： C12M23/14 ,  C12M29/06

摘要： A cell culture media container is provided. The container comprises a body constructed from flexible film and defining a containment area for containing the cell culture media, the body including a front face and a back face, the front and back face being sealed to each other along at least three sides thereof. The container includes a fill port for filling the containment area with cell culture media, the port being sealed to a face of the body and being so constructed and arranged that it extends from the face normal thereto. The container is constructed from a high barrier, optically clear, radiation sterilizable film.

摘要翻译： 提供细胞培养基容器。 容器包括由柔性膜构成的主体并且限定用于容纳细胞培养基的容纳区域，所述容器包括前表面和后表面，所述前表面和后表面沿着其至少三个侧面被彼此密封。 容器包括用于用容纳细胞培养基填充容纳区域的填充口，该孔口被密封到主体的表面，并被构造和布置成使得其从正面与其正面延伸。 容器由高屏障，光学透明的辐射灭菌膜构成。

公开(公告)号：US06508800B1

公开(公告)日：2003-01-21

申请号：US09349688

申请日：1999-07-08

申请人： Michael R. Keilman ,  Walter A. Makaryk ,  Joseph A. Giertych

发明人： Michael R. Keilman ,  Walter A. Makaryk ,  Joseph A. Giertych

IPC分类号： A61B1900

CPC分类号： A61M1/28 ,  A61J1/00 ,  A61M1/1668 ,  A61M1/1686 ,  Y10S128/24 ,  Y10S206/828 ,  Y10T436/108331

摘要： A dual-filled twin bag, a packaging including the twin bag, and a method for forming the packaged twin bags are provided. Each of two bags, a solution bag (10)and a drain bag (12) for a system used for a peritoneal dialysis procedure, are filled, at least partially, with a solution (14). A tubing set (16) connects the two filled bags (10,12) and may also be filled with solution (14) which is added to the bags (10,12) and the tubing set (16) during the manufacturing process. Alternatively, the tubing set (16) may be filled with air. The tubing set (16) is sandwiched between the solution bag (10) and the drain bag (12) and subsequently packaged in an overpouch (24). The method for forming the package including the bags filled with solution is simplified and the overall package size is reduced due to the sandwiched tubing set (16) between the solution bags (10,12) and the provision of solution in both bags (10,12).

摘要翻译： 提供双填充双袋，包括双包的包装以及用于形成包装的双袋的方法。 至少部分地用溶液（14）填充两个袋子中的每个袋，溶液袋（10）和用于腹膜透析程序的系统的排液袋（12）。 管道组（16）连接两个填充的袋（10,12），并且还可以在制造过程中填充有添加到袋（10,12）和管组（16）的溶液（14）。 或者，管组（16）可以填充空气。 管套（16）夹在溶液袋（10）和排放袋（12）之间，随后包装在一个外袋（24）中。 用于形成包括填充有溶液的袋的包装的方法被简化，并且由于溶液袋（10,12）之间的夹套管组（16）和在两个袋（10,12）中提供溶液，整体包装尺寸减小， 12）。

公开(公告)号：US6012578A

公开(公告)日：2000-01-11

申请号：US4266

申请日：1998-01-08

申请人： Michael R. Keilman

发明人： Michael R. Keilman

IPC分类号： A61J1/00 ,  A61J1/05 ,  A61M1/28 ,  A61B17/06

CPC分类号： A61M1/28 ,  A61J1/10 ,  Y10S206/828

摘要： A dual-filled twin bag, a packaging including the twin bag, and a method for forming the packaged twin bags are provided. Each of two bags, a solution bag (10) and a drain bag (12) for a system used for a peritoneal dialysis procedure, are filled, at least partially, with a solution (14). A tubing set (16) connects the two filled bags (10,12) and may also be filled with solution (14) which is added to the bags (10,12) and the tubing set (16) during the manufacturing process. The tubing set (16) is sandwiched between the solution bag (10) and the drain bag (12) and subsequently packaged in an overpouch (24). The method for forming the package including the bags filled with solution is simplified and the overall package size is reduced due to the sandwiched tubing set (16) between the solution bags (10,12) and the provision of solution in both bags (10,12).

摘要翻译： 提供双填充双袋，包括双包的包装以及用于形成包装的双袋的方法。 至少部分地用溶液（14）填充两个袋子中的每个袋，溶液袋（10）和用于腹膜透析程序的系统的排液袋（12）。 管道组（16）连接两个填充的袋（10,12），并且还可以在制造过程中填充有添加到袋（10,12）和管组（16）的溶液（14）。 管套（16）夹在溶液袋（10）和排放袋（12）之间，随后包装在一个外袋（24）中。 用于形成包括填充有溶液的袋的包装的方法被简化，并且由于溶液袋（10,12）之间的夹套管组（16）和在两个袋（10,12）中提供溶液，整体包装尺寸减小， 12）。

公开(公告)号：US4717668A

公开(公告)日：1988-01-05

申请号：US940889

申请日：1986-12-12

申请人： Michael R. Keilman ,  Ronald P. Symbol

发明人： Michael R. Keilman ,  Ronald P. Symbol

IPC分类号： C12M3/04 ,  C12M1/24

CPC分类号： C12M27/12 ,  C12M23/08 ,  C12M23/26 ,  C12M37/00 ,  Y10S215/03

摘要： A plastic roller bottle is provided for suspension cultures for bacteriology or other cell growth or maintenance. The roller bottle comprises a closed bottle defining a longitudinal axis and having flexible plastic walls. Aseptically sealable means for access into the closed body are provided as well. A plurality of spaced reinforcement rings are defined in the flexible plastic walls about the longitudinal axis, to cause the body to normally retain a predetermined, generally cylindrical shape. The flexible plastic walls, apart from the rings, are made of a plastic formulation, and are of a thickness such that the oxygen and carbon dioxide diffusion which takes place through said walls is sufficient to support desired biochemical culturing processes taking place within the roller bottle without venting.

摘要翻译： 为悬浮培养物提供塑料滚瓶用于细菌学或其他细胞生长或维持。 辊瓶包括限定纵向轴线并具有柔性塑料壁的封闭瓶。 还提供用于进入封闭体的无菌密封装置。 在柔性塑料壁中围绕纵向轴线限定多个间隔开的加强环，以使得主体通常保持预定的大致圆柱形形状。 除了环之外，柔性塑料壁由塑料制剂制成，并且具有使得通过所述壁发生的氧气和二氧化碳扩散足以支撑在辊瓶内发生的期望的生化培养过程的厚度 没有通风。

公开(公告)号：USD291004S

公开(公告)日：1987-07-21

申请号：US534474

申请日：1983-09-21

申请人： Michael R. Keilman ,  Richard L. West

设计人： Michael R. Keilman ,  Richard L. West

公开(公告)号：US06764482B2

公开(公告)日：2004-07-20

申请号：US10283654

申请日：2002-10-29

申请人： Michael R. Keilman ,  Walter A. Makaryk ,  Joseph A. Giertych

发明人： Michael R. Keilman ,  Walter A. Makaryk ,  Joseph A. Giertych

IPC分类号： A61B1900

CPC分类号： A61M1/28 ,  A61J1/00 ,  A61M1/1668 ,  A61M1/1686 ,  Y10S128/24 ,  Y10S206/828 ,  Y10T436/108331

摘要： A dual-filled twin bag, a packaging including the twin bag, and a method for forming the packaged twin bags are provided. Each of two bags, a solution bag (10) and a drain bag (12) for a system used for a peritoneal dialysis procedure, are filled, at least partially, with a solution (14). A tubing set (16) connects the two filled bags (10,12) and may also be filled with solution (14) which is added to the bags (10,12) and the tubing set (16) during the manufacturing process. Alternatively, the tubing set (16) may be filled with air. The tubing set (16) is sandwiched between the solution bag (10) and the drain bag (12) and subsequently packaged in an overpouch (24). The method for forming the package including the bags filled with solution is simplified and the overall package size is reduced due to the sandwiched tubing set (16) between the solution bags (10,12) and the provision of solution in both bags (10,12).

摘要翻译： 提供双填充双袋，包括双包的包装以及用于形成包装的双袋的方法。 至少部分地用溶液（14）填充两个袋子中的每个袋，溶液袋（10）和用于腹膜透析程序的系统的排液袋（12）。 管道组（16）连接两个填充的袋（10,12），并且还可以在制造过程中填充有添加到袋（10,12）和管组（16）中的溶液（14）。 或者，管组（16）可以填充空气。 管套（16）夹在溶液袋（10）和排放袋（12）之间，随后包装在一个外袋（24）中。 用于形成包括填充有溶液的袋的包装的方法被简化，并且由于溶液袋（10,12）之间的夹套管组（16）和在两个袋（10,12）中提供溶液，整体包装尺寸减小， 12）。

公开(公告)号：US06196992B1

公开(公告)日：2001-03-06

申请号：US08963296

申请日：1997-11-03

申请人： Michael R. Keilman ,  Kelly B. Smith

发明人： Michael R. Keilman ,  Kelly B. Smith

IPC分类号： A61M3100

CPC分类号： A61M1/28 ,  A61M1/1609 ,  A61M1/281

摘要： A portable pump apparatus for use in CAPD is provided as well as a method for providing CAPD to a patient. The portable pump apparatus for CAPD has a housing containing a pump, and a power supply, preferably a rechargeable battery, connected to the housing and electrically connected to drive the pump. A control knob on the housing is constructed and arranged to adjust the speed of the pump. A cover is mounted to the housing to enclose the pump. The cover has an inlet port and an outlet port to securely hold a tube thereunder. The portable pump apparatus for CAPD further has a display for providing drainage information and a clip so that the apparatus can be worn by a patient.

摘要翻译： 提供了一种用于CAPD的便携式泵装置以及向患者提供CAPD的方法。 用于CAPD的便携式泵装置具有容纳泵的壳体，以及连接到壳体并电连接以驱动泵的电源，优选地是可再充电电池。 壳体上的控制旋钮被构造和布置以调节泵的速度。 一个盖子安装在壳体上以封闭泵。 盖子有一个入口和一个出口，用于牢固地固定一根管子。 用于CAPD的便携式泵装置还具有用于提供排水信息和夹子的显示器，使得该装置可以由患者佩戴。

公开(公告)号：US5984891A

公开(公告)日：1999-11-16

申请号：US003911

申请日：1998-01-07

申请人： Michael R. Keilman ,  Kelly B. Smith

发明人： Michael R. Keilman ,  Kelly B. Smith

IPC分类号： A61M1/16 ,  A61M1/28 ,  A61M31/00

CPC分类号： A61M1/28 ,  A61M1/1609 ,  A61M1/281

摘要： A portable pump apparatus for use in CAPD is provided as well as a method for providing CAPD to a patient. The portable pump apparatus for CAPD has a housing containing a pump, and a power supply, preferably a rechargeable battery, connected to the housing and electrically connected to drive the pump. A control knob on the housing is constructed and arranged to adjust the speed of the pump. A cover is mounted to the housing to enclose the pump. The cover has an inlet port and an outlet port to securely hold a tube thereunder. The portable pump apparatus for CAPD further has a display for providing drainage information and a clip so that the apparatus can be worn by a patient.

摘要翻译： 提供了一种用于CAPD的便携式泵装置以及向患者提供CAPD的方法。 用于CAPD的便携式泵装置具有容纳泵的壳体，以及连接到壳体并电连接以驱动泵的电源，优选地是可再充电电池。 壳体上的控制旋钮被构造和布置以调节泵的速度。 一个盖子安装在壳体上以封闭泵。 盖子有一个入口和一个出口，用于牢固地固定一根管子。 用于CAPD的便携式泵装置还具有用于提供排水信息和夹子的显示器，使得该装置可以由患者佩戴。

公开(公告)号：US5820582A

公开(公告)日：1998-10-13

申请号：US646647

申请日：1996-05-03

申请人： Michael R. Keilman

发明人： Michael R. Keilman

IPC分类号： A61J1/00 ,  A61M1/28 ,  A61M31/00

CPC分类号： A61J1/00 ,  A61M1/28 ,  A61J1/10

摘要： A dual-filled twin bag, a packaging including the twin bag, and a method for forming the packaged twin bags are provided. Each of two bags, a solution bag (10) and a drain bag (12) for a system used for a peritoneal dialysis procedure, are filled, at least partially, with a solution (14). A tubing set (16) connects the two filled bags (10, 12) and may also be filled with solution (14) which is added to the bags (10, 12) and the tubing set (16) during the manufacturing process. The tubing set (16) is sandwiched between the solution bag (10) and the drain bag (12) and subsequently packaged in an overpouch (24). The method for forming the package including the bags filled with solution is simplified and the overall package size is reduced due to the sandwiched tubing set (16) between the solution bags (10, 12) and the provision of solution in both bags (10, 12).

摘要翻译： 提供双填充双袋，包括双包的包装以及用于形成包装的双袋的方法。 至少部分地用溶液（14）填充两个袋子中的每个袋，溶液袋（10）和用于腹膜透析程序的系统的排液袋（12）。 管道组（16）连接两个填充的袋（10,12），并且还可以填充溶液（14），其在制造过程中被添加到袋（10,12）和管组（16）中。 管套（16）夹在溶液袋（10）和排放袋（12）之间，随后包装在一个外袋（24）中。 用于形成包括填充有溶液的袋的包装的方法被简化，并且由于溶液袋（10,12）之间的夹套管组（16）和在两个袋（10,12）中提供溶液，整体包装尺寸减小， 12）。

公开(公告)号：US06196991B1

公开(公告)日：2001-03-06

申请号：US09127511

申请日：1998-07-31

申请人： Michael R. Keilman

发明人： Michael R. Keilman

IPC分类号： A61M100

CPC分类号： A61J1/00 ,  A61J1/10 ,  A61M1/1668 ,  A61M1/1686 ,  A61M1/28

摘要： A dual-filled twin bag, a packaging including the twin bag, and a method for forming the packaged twin bags are provided. Each of two bags, a solution bag (10) and a drain bag (12) for a system used for a peritoneal dialysis procedure, are filled, at least partially, with a solution (14). A tubing set (16) connects the two filled bags (10,12) and may also be filled with solution (14) which is added to the bags (10,12) and the tubing set (16) during the manufacturing process. The tubing set (16) is sandwiched between the solution bag (10) and the drain bag (12) and subsequently packaged in an overpouch (24). The method for forming the package including the bags filled with solution is simplified and the overall package size is reduced due to the sandwiched tubing set (16) between the solution bags (10,12) and the provision of solution in both bags (10,12).

摘要翻译： 提供双填充双袋，包括双包的包装以及用于形成包装的双袋的方法。 至少部分地用溶液（14）填充两个袋子中的每个袋，溶液袋（10）和用于腹膜透析程序的系统的排液袋（12）。 管道组（16）连接两个填充的袋（10,12），并且还可以在制造过程中填充有添加到袋（10,12）和管组（16）中的溶液（14）。 管套（16）夹在溶液袋（10）和排放袋（12）之间，随后包装在一个外袋（24）中。 用于形成包括填充有溶液的袋的包装的方法被简化，并且由于溶液袋（10,12）之间的夹套管组（16）和在两个袋（10,12）中提供溶液，整体包装尺寸减小， 12）。