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    Composition in the form of a water-in-oil emulsion having a changing shear rate
    11.
    发明授权
    Composition in the form of a water-in-oil emulsion having a changing shear rate 失效
    具有变化剪切速率的油包水乳液形式的组合物

    公开(公告)号：US06331306B1

    公开(公告)日：2001-12-18

    申请号：US09343527

    申请日：1999-06-30

    Applicant: Isabelle Afriat ,  Virginie Boulier

    Inventor： Isabelle Afriat ,  Virginie Boulier

    IPC: A61K748

    CPC classification number: A61K8/894 ,  A61K8/064 ,  A61K8/20 ,  A61Q19/00 ,  A61Q19/007 ,  Y10S514/844 ,  Y10S514/863 ,  Y10S514/937 ,  Y10S514/938 ,  Y10S514/944

    Abstract: A cosmetic or dermatological composition, comprising: an aqueous phase dispersed in an oily phase with a silicone emulsifying agent, wherein the viscosity of the composition, measured with a Rheomat 180 viscometer at a shear rate of 200 s−1 and at 25° C., ranges from 3 Pa.s (30 poises) to 20 Pa.s (200 poises), the aqueous phase constituting at least 78% by weight with respect to the total weight of the composition with the water of the aqueous phase constituting at least 65% of the total weight of the composition, and the emulsifying agent consisting of the dimethicone copolyol of formula (I): wherein R1 is

    Abstract translation: 一种化妆品或皮肤病学组合物，其包含：用硅氧烷乳化剂分散在油相中的水相，其中所述组合物的粘度用Rheomat 180粘度计在200s -1的剪切速率和25℃下测量。 的范围为3Pa.s（30泊）至20Pa.s（200泊），水相相对于组合物的总重量至少为78重量％，水相的水构成至少 组合物总重量的65％，由式（I）的聚二甲基硅氧烷共聚多元醇组成的乳化剂：其中R1为

    Emulsion containing ascorbic acid and its uses in the cosmetics and dermatological fields
    14.
    发明授权
    Emulsion containing ascorbic acid and its uses in the cosmetics and dermatological fields 有权
    含有抗坏血酸的乳液及其在化妆品和皮肤病领域的应用

    公开(公告)号：US06465510B2

    公开(公告)日：2002-10-15

    申请号：US09801755

    申请日：2001-03-09

    Applicant: Isabelle Afriat ,  Florence Chanvin

    Inventor： Isabelle Afriat ,  Florence Chanvin

    IPC: A61K3134

    CPC classification number: A61Q17/00 ,  A61K8/06 ,  A61K8/064 ,  A61K8/676 ,  A61K8/894 ,  A61Q19/00 ,  A61Q19/08 ,  Y10S514/928

    Abstract: A water-in-oil emulsion containing ascorbic acid and, as an emulsifier, a dimethiconecopolyol or an alkyldimethiconecopolyol, where the aqueous phase having a pH ranging from 5.5 to 7.5. This emulsion allows ascorbic acid to be stabilized and can be used, in particular, in the cosmetics and/or dermatological fields. The invention also relates to a cosmetic process for treating the skin using the emulsion.

    Abstract translation: 含有抗坏血酸的油包水乳液，以及作为乳化剂的二甲基聚多元醇或烷基二甲基多羟基苯甲醇，其中水相的pH为5.5-7.5。 该乳液使抗坏血酸稳定，特别可用于化妆品和/或皮肤病学领域。 本发明还涉及使用乳液处理皮肤的美容方法。

    Use of a silicone gum to stabilize ascorbic acid, and novel compositions comprising these components
    15.
    发明授权
    Use of a silicone gum to stabilize ascorbic acid, and novel compositions comprising these components 失效
    使用硅酮胶稳定抗坏血酸，以及包含这些组分的新型组合物

    公开(公告)号：US06328983B1

    公开(公告)日：2001-12-11

    申请号：US09408448

    申请日：1999-09-29

    Applicant: Isabelle Afriat

    Inventor： Isabelle Afriat

    IPC: A61K700

    CPC classification number: A61Q17/00 ,  A61K8/676 ,  A61K8/891 ,  A61K2800/52

    Abstract: The present invention relates to the use of a silicone gum to stabilize ascorbic acid or one of its esters or salts in a topical composition and to novel compositions comprising these components and having a pH of from 4 to 7. These compositions can be used in the fields of cosmetology, dermatology and veterinary medicine.

    Abstract translation: 本发明涉及硅胶在稳定抗坏血酸或其局部组合物中的酯或其盐之一的用途以及包含这些组分并具有4至7的pH的新型组合物。这些组合物可用于 美容，皮肤科，兽医领域。

    Method of evaluating the effects of exogenous and endogenous factors on the skin
    16.
    发明申请
    Method of evaluating the effects of exogenous and endogenous factors on the skin 审中-公开
    评估外源和内源因素对皮肤的影响的方法

    公开(公告)号：US20070125390A1

    公开(公告)日：2007-06-07

    申请号：US11296236

    申请日：2005-12-07

    Applicant: Isabelle Afriat ,  Miriam Rafailovich ,  E. Guan

    Inventor： Isabelle Afriat ,  Miriam Rafailovich ,  E. Guan

    IPC: A61B19/00 ,  G06K9/00

    CPC classification number: A61B5/445 ,  A61B5/0088 ,  A61B5/442

    Abstract: The present invention provides non-invasive, in vivo, DISC-type methods of evaluating structural changes in skin due to a variety of exogenous or endogenous factors. It is possible to develop quantitative and qualitative characterizations of skin. For example, the skin may be characterized based on its structural age rather than its chronological age. Based on the structural age and type of an individual's skin, cosmetic, dermatologic, medicinal or manipulative treatment may be customized. The method is based, in part, on quantification of discontinuities that arise in the skin during normal facial expression. The methods provide for evaluating changes in human skin response that occur over a short term (one day) or long term (one or more years). The methods provide for evaluating the skin's response to cosmetic, dermatologic or medicinal treatment or to any other factor alleged to affect the skin.

    Abstract translation: 本发明提供了由多种外源或内源因素评价皮肤结构变化的非侵入式体内DISC型方法。 可以开发皮肤的定量和定性表征。 例如，皮肤可以基于其结构年龄而不是其时间年龄来表征。 根据个人皮肤的结构年龄和类型，可以定制化妆品，皮肤病学，药物或操作性治疗。 该方法部分地基于在正常面部表情期间在皮肤中产生的不连续性的量化。 这些方法用于评估短期（一天）或长期（一年或多年）发生的人类皮肤反应变化。 该方法用于评估皮肤对化妆品，皮肤病学或药物治疗的反应或任何其他影响皮肤的因素。

    Composition in the form of a water-in-oil emulsion having an evolutive shear rate
    18.
    发明授权
    Composition in the form of a water-in-oil emulsion having an evolutive shear rate 失效
    具有演变剪切速率的油包水乳液形式的组合物

    公开(公告)号：US06562354B1

    公开(公告)日：2003-05-13

    申请号：US09611312

    申请日：2000-07-06

    Applicant: Isabelle Afriat ,  Virginie Boulier

    Inventor： Isabelle Afriat ,  Virginie Boulier

    IPC: A61K600

    CPC classification number: A61K8/894 ,  A61K8/06 ,  A61K8/064 ,  A61K8/20 ,  A61Q1/00 ,  A61Q19/00 ,  A61Q19/004 ,  A61Q19/008 ,  B01F17/0071 ,  Y10S514/937

    Abstract: The present provides a composition that includes, in a physiologically acceptable medium: an aqueous phase dispersed in an oily phase with a silicone emulsifier; wherein the aqueous phase represents at least 80% by weight relative to the total weight of the composition; wherein the silicone emulsifier is an alkyldimethicone copolyol comprising an HLB of less than 8; and wherein a weight ratio of the oily phase to the silicone emulsifier is greater than or equal to 5. The present invention also provides a cosmetic, which includes the above-mentioned composition and methods of using the above-mentioned composition for treating, protecting, caring for, or removing make-up from the skin, lips or hair, cleansing the skin, lips or hair, and making up the skin or lips, treating, protecting, and caring for the scalp, and treating greasy skin. The composition can be used in particular in cosmetics and/or dermatology.

    Abstract translation: 本发明提供一种组合物，其在生理学上可接受的培养基中包含：分散在油相中的水相与硅氧烷乳化剂;其中所述水相相对于所述组合物的总重量为至少80重量％;其中所述硅氧烷 乳化剂是包含小于8的HLB的烷基二甲基聚硅氧烷共聚醇; 并且其中油相与硅氧烷乳化剂的重量比大于或等于5.本发明还提供了一种化妆品，其包括上述组合物和使用上述组合物用于处理，保护，保养的方法 用于或从皮肤，嘴唇或头发上除去化妆品，清洁皮肤，嘴唇或头发，以及组合皮肤或嘴唇，治疗，保护和照顾头皮，以及治疗油腻的皮肤。 该组合物特别可用于化妆品和/或皮肤病学。

    Emulsion containing ascorbic acid and its uses in the cosmetics and dermatological fields
    20.
    发明授权
    Emulsion containing ascorbic acid and its uses in the cosmetics and dermatological fields 失效
    含有抗坏血酸的乳液及其在化妆品和皮肤病领域的应用

    公开(公告)号：US06239174B1

    公开(公告)日：2001-05-29

    申请号：US09145611

    申请日：1998-09-02

    Applicant: Isabelle Afriat ,  Florence Chanvin

    Inventor： Isabelle Afriat ,  Florence Chanvin

    IPC: A61K3134

    CPC classification number: A61Q17/00 ,  A61K8/06 ,  A61K8/064 ,  A61K8/676 ,  A61K8/894 ,  A61Q19/00 ,  A61Q19/08

    Abstract: A water-in-oil emulsion containing ascorbic acid and, as an emulsifier, a dimethiconecopolyol or an alkyldimethiconecopolyol, where the aqueous phase having a pH ranging from 6.1 to 7.5. This emulsion allows ascorbic acid to be stabilized and can be used, in particular, in the cosmetics and/or dermatological fields. The invention also relates to a cosmetic process for treating the skin using the emulsion.

    Abstract translation: 含有抗坏血酸的油包水乳液，以及作为乳化剂的二甲基聚多元醇或烷基二甲基表醇多元醇，其中水相的pH为6.1至7.5。 该乳液使抗坏血酸稳定，特别可用于化妆品和/或皮肤病学领域。 本发明还涉及使用乳液处理皮肤的美容方法。

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