Methods for detecting therapeutic effects of anti-cancer drugs by monitoring changes in gut flora
    11.
    发明授权
    Methods for detecting therapeutic effects of anti-cancer drugs by monitoring changes in gut flora 有权
    通过监测肠道菌群变化来检测抗癌药物的治疗效果的方法

    公开(公告)号:US08097417B2

    公开(公告)日:2012-01-17

    申请号:US12380103

    申请日:2009-02-23

    IPC分类号: C12Q1/68 C12P19/34

    CPC分类号: C12Q1/6886 C12Q1/6888

    摘要: Non-invasive methods for monitoring the effect of an agent for treating colorectal cancer, comprising (1) collecting fecal samples from healthy subjects, subjects having precancerous lesions, and subject having precancerous lesions and being treated with an anti-cancer agent; (2) isolating total microbial genomic DNA from the fecal samples to provide total microbial genomic DNA; (3) comparing the total microbial genomic DNA using fingerprint spectrum analysis; (4) identifying key fingerprint bands correlated with the effect of the anti-cancer agent; (5) identifying key microorganisms associated with the key fingerprint bands; (6) designing microbial sequence-specific primers and probes; and (7) determining the quantitative differences of the key microorganisms in fecal samples to identify an indicator microorganism for monitoring the effect of the anti-cancer agent.

    摘要翻译: 用于监测药物治疗结肠直肠癌的效果的非侵入性方法,包括(1)从健康受试者收集粪便样品,患有癌前病变的受试者和患有癌前病变的受试者并用抗癌剂治疗; (2)从粪便样品中分离总微生物基因组DNA以提供总微生物基因组DNA; (3)使用指纹谱分析比较总微生物基因组DNA; (4)识别与抗癌剂作用相关的关键指纹带; (5)识别与关键指纹带相关的关键微生物; (6)设计微生物序列特异性引物和探针; 和(7)确定粪便样品中关键微生物的定量差异,以鉴定用于监测抗癌剂效果的指示剂微生物。

    FUME HOOD SYSTEM HAVING AN AUTOMATIC DECOMMISSION MODE
    12.
    发明申请
    FUME HOOD SYSTEM HAVING AN AUTOMATIC DECOMMISSION MODE 审中-公开
    具有自动退化模式的FUME HOOD系统

    公开(公告)号:US20090191803A1

    公开(公告)日:2009-07-30

    申请号:US12019223

    申请日:2008-01-24

    IPC分类号: B08B15/02

    CPC分类号: B08B15/02

    摘要: A fume hood system having a decommissioned mode. A fume hood may be required to maintain a minimum flow from its enclosure holding fume type substances via an exhaust external to the hood. However, if the fume hood is considered not in use or not containing fume type substances, it may be put into a decommissioned mode not necessarily having a flow requirement. This mode may be entered by pressing a sequence of buttons on a monitor, operating a switch, receiving a signal from a building management system, or the like, provided that certain criteria for non-use are met by the fume hood. The decommissioned mode may also be entered or exited automatically. Status of the fume hood, as to in-use or decommissioned, may be reported to a building management system for monitoring, reporting, and/or command purposes.

    摘要翻译: 具有退役模式的通风柜系统。 可能需要通风柜来保持其外壳中保持烟雾型物质的最小流量,通过罩外部的排气。 然而,如果通风橱被认为不使用或不含烟雾型物质,则其可以进入不一定具有流动要求的退役模式。 如果通风柜满足某些不使用的标准,则可以通过按下监视器上的一系列按钮,操作开关,从建筑物管理系统接收信号等来输入该模式。 退役模式也可以自动输入或退出。 通风柜的状态,在使用或停用时,可能会报告给建筑物管理系统进行监测,报告和/或指挥。

    Intracardiac energy harvesting device and implantable electronic medical device

    公开(公告)号:US11992688B2

    公开(公告)日:2024-05-28

    申请号:US17917925

    申请日:2020-05-26

    申请人: Wei Hua Zhou Li

    IPC分类号: A61N1/378 A61N1/37 A61N1/375

    CPC分类号: A61N1/37 A61N1/375 A61N1/3785

    摘要: An intracardiac energy harvesting device includes a shell; a fixing mechanism arranged on the shell, and a fixing mechanism configured to fix the shell to an interior of a heart chamber to enable the shell to move along with beating of heart; wherein a nanogenerator module is packaged in the shell, which is configured to output electric energy in response to movement of the shell along with the heart beat; and a power management module is packaged in the shell for managing electric energy output by the nanogenerator module. According to the intracardiac energy collecting device disclosed by the present invention, the biological mechanical energy generated by heart beating can be collected in the heart through a minimally invasive interventional operation mode, surgical wounds are small, damage to the heart cannot be caused, and infection can be effectively avoided.

    Intracardiac energy harvesting device and implantable electronic medical device

    公开(公告)号:US20230149720A1

    公开(公告)日:2023-05-18

    申请号:US17917925

    申请日:2020-05-26

    申请人: Wei Hua Zhou Li

    IPC分类号: A61N1/37 A61N1/378 A61N1/375

    CPC分类号: A61N1/37 A61N1/3785 A61N1/375

    摘要: An intracardiac energy harvesting device includes a shell; a fixing mechanism arranged on the shell, and a fixing mechanism configured to fix the shell to an interior of a heart chamber to enable the shell to move along with beating of heart; wherein a nanogenerator module is packaged in the shell, which is configured to output electric energy in response to movement of the shell along with the heart beat; and a power management module is packaged in the shell for managing electric energy output by the nanogenerator module. According to the intracardiac energy collecting device disclosed by the present invention, the biological mechanical energy generated by heart beating can be collected in the heart through a minimally invasive interventional operation mode, surgical wounds are small, damage to the heart cannot be caused, and infection can be effectively avoided.

    Method to Predict a Communicative Action that is Most Likely to be Executed Given a Context
    15.
    发明申请
    Method to Predict a Communicative Action that is Most Likely to be Executed Given a Context 审中-公开
    预测给予上下文最可能执行的沟通行为的方法

    公开(公告)号:US20130346347A1

    公开(公告)日:2013-12-26

    申请号:US13568957

    申请日:2012-08-07

    IPC分类号: G06F15/18

    摘要: Disclosed are apparatus and methods for providing machine-learning services. A context-identification system executing on a mobile platform can receive data comprising context-related data associated with the mobile platform and application-related data received from the mobile platform. The context-identification system can identify a context using the context-related data associated with the mobile platform and/or the application-related data received from the mobile platform. Based on at least one context identified, context-identification system can predict a communicative action associated with the mobile platform by performing a machine-learning operation on the received data. An instruction can be received to execute the communicative action associated with the mobile platform.

    摘要翻译: 公开了用于提供机器学习服务的装置和方法。 在移动平台上执行的上下文识别系统可以接收包括与移动平台相关联的上下文相关数据的数据和从移动平台接收的应用相关数据。 上下文识别系统可以使用与移动平台相关联的上下文相关数据和/或从移动平台接收的应用相关数据来识别上下文。 基于所识别的至少一个上下文,上下文识别系统可以通过对接收到的数据执行机器学习操作来预测与移动平台相关联的交互动作。 可以接收指令来执行与移动平台相关联的交互动作。

    Native machine learning service for user adaptation on a mobile platform
    16.
    发明授权
    Native machine learning service for user adaptation on a mobile platform 有权
    在移动平台上进行用户自适应的本地机器学习服务

    公开(公告)号:US08429103B1

    公开(公告)日:2013-04-23

    申请号:US13565508

    申请日:2012-08-02

    IPC分类号: G06F15/18 G09B19/00

    摘要: Disclosed are apparatus and methods for providing machine-learning services. A machine-learning service executing on a mobile platform can receive data related to a plurality of features. In some cases, the received data can include data related to features received from an application and data related to features received from the mobile platform. The machine-learning service can determine at least one feature based on the received data. The machine-learning service can generate an output by performing a machine-learning operation on the at least one feature. The machine-learning operation can be selected from among an operation of ranking the at least one feature, an operation of classifying the at least one feature, an operation of predicting the at least one feature, and an operation of clustering the at least one feature. The machine-learning service can send the output.

    摘要翻译: 公开了用于提供机器学习服务的装置和方法。 在移动平台上执行的机器学习服务可以接收与多个特征相关的数据。 在一些情况下,所接收的数据可以包括与从应用接收的特征有关的数据以及与从移动平台接收的特征有关的数据。 机器学习服务可以基于接收到的数据来确定至少一个特征。 机器学习服务可以通过对至少一个特征执行机器学习操作来生成输出。 可以从对至少一个特征进行排序的操作,对至少一个特征进行分类的操作,预测至少一个特征的操作,以及对至少一个特征进行聚类的操作来选择机器学习操作 。 机器学习服务可以发送输出。

    Use of a Chimeric Gene 4-CL Encoding 4-Coumarate:CoA Ligase in Brassicaceae
    17.
    发明申请
    Use of a Chimeric Gene 4-CL Encoding 4-Coumarate:CoA Ligase in Brassicaceae 审中-公开
    使用编码4-香豆素的嵌合基因4-CL:芸苔科中的CoA连接酶

    公开(公告)号:US20110072538A1

    公开(公告)日:2011-03-24

    申请号:US12993802

    申请日:2008-11-25

    CPC分类号: C12N15/8255 C12N15/8282

    摘要: The use of a lignin monomer synthetic gene 4-CL encoding 4-coumarate: CoA ligase from Populus tomentosa in increasing Sclerotinia resistance and lodging resistance. The 4-CL gene is responsible for catalyzing various cinnamic acids and their derivatives to produce respective coenzyme A esters, involved in the synthesis of various downstream secondary products, and is the key gene in the regulation of lignin synthesis. Results of the study show that, increase of lignin content improves plant's resistance against pathogenic infection, enhances the stem strength of rape, and thus significantly improves the lodging resistance. Specifically, the result shows that lignin content of transgenic rape increases more than 10% compared to lignin content of recipient control; lesion extension area of transgenic plant leaves decreases around 30% compared to recipient control; and stem strength of transgenic plant increases up to around 20% compared to control.

    摘要翻译: 使用木质素单体合成基因4-CL编码4-香豆酸:来自山杨的CoA连接酶增加核盘菌素耐药性和耐倒伏性。 4-CL基因负责催化各种肉桂酸及其衍生物,产生各种辅酶A酯,涉及多种下游二级产物的合成,是木质素合成调控的关键基因。 研究结果表明,木质素含量的增加提高了植物对病原菌感染的抵抗力,提高了强奸的茎强度,从而显着提高了抗倒伏性。 具体来说,结果表明,转基因油菜的木质素含量与受体对照的木质素含量相比增加10%以上; 转基因植物叶片病变延伸面积比受体控制下降约30%; 转基因植物茎干强度与对照相比增加了约20%。

    System and method for servoing on a moving fixation point within a dynamic scene

    公开(公告)号:US07027083B2

    公开(公告)日:2006-04-11

    申请号:US10074314

    申请日:2002-02-12

    IPC分类号: H04N7/18

    摘要: A system and method for servoing on a moving target within a dynamic scene. According to one embodiment, the system includes a master variable pointing camera system and a plurality of slave variable pointing camera systems positioned around the scene. The system also includes a master control unit in communication with the master variable pointing camera system. The master control unit is for determining, based on parameters of the master variable pointing camera system, parameters for each of the slave variable pointing camera systems such that, at a point in time, the master variable pointing camera system and the slave variable pointing camera systems are aimed at the target and a size of the target in an image from each of the master variable pointing camera system and the slave variable pointing camera systems is substantially the same. The system also includes a plurality of slave camera control units in communication with the master control unit. The slave camera control units are for controlling at least one of the slave variable pointing camera systems based on the parameters for each of the slave variable pointing camera systems. The system may also include a video image sequence generator in communication with the master control unit and the slave camera control units. The video image sequence generator may generate a video image sequence of the target by outputting an image from certain of the master variable pointing camera system and the slave variable pointing camera systems in sequence according to the position of the master variable pointing camera system and the slave variable pointing camera systems around the scene.