公开(公告)号：US20140125336A1

公开(公告)日：2014-05-08

申请号：US14054914

申请日：2013-10-16

Applicant: Xiaodong Zhong ,  Marcel Dominik Nickel ,  Stephan Kannengiesser

Inventor： Xiaodong Zhong ,  Marcel Dominik Nickel ,  Stephan Kannengiesser

IPC: G01R33/48 ,  G01R33/50

CPC classification number: G01R33/4828 ,  G01R33/50

Abstract: Embodiments relate to evaluating properties of tissues with magnetic resonance imaging (MRI). A MR image is used to measure a characteristic that influences a particular chemical property of a tissue. In an exemplary embodiment, tissue transverse relaxation values or relaxation rates, which can readily be measured from MR images, are used to evaluate iron deposition in tissue. Iron deposition influences the tissue transverse relaxation values (T2 or T2*) or relaxation rates (R2=1/T2 or R2*=1/T2*). A clinically relevant R2CR* map is calculated based on the known values of the effective R2eff*, the water R2w*, and the fat R2f* by incorporating the most relevant value for each individual image element of a plurality of image elements of an MR image of the tissue. The clinically relevant R2CR* map provides an accurate evaluation of iron deposition in any region of the tissue with the use of one map.

Abstract translation: 实施例涉及评估具有磁共振成像（MRI）的组织的性质。 MR图像用于测量影响组织的特定化学性质的特征。 在示例性实施例中，可以容易地从MR图像测量的组织横向松弛值或松弛率用于评估组织中的铁沉积。 铁沉积影响组织横向弛豫值（T2或T2 *）或松弛率（R2 = 1 / T2或R2 * = 1 / T2 *）。 基于有效R2eff *，水R2w *和脂肪R2f *的已知值，通过对MR图像的多个图像元素的每个单独图像元素合并最相关值来计算临床相关的R2CR *图 的组织。 临床上相关的R2CR *图谱使用一张地图提供组织任何区域铁沉积的准确评估。

公开(公告)号：US20140062479A1

公开(公告)日：2014-03-06

申请号：US14013143

申请日：2013-08-29

Applicant: Stephan Kannengiesser

Inventor： Stephan Kannengiesser

IPC: G01R33/48

CPC classification number: G01R33/4828

Abstract: In a method and apparatus to determine a magnetic resonance image of an examination subject with at least two spin species by using a chemical shift imaging multi-echo MR measurement sequence, first approximated MR image is determined based on a first approximative model and of a second approximated MR image is determined based on a second approximative model, wherein the first and second approximative model respectively express an MR signal under consideration of one or more MR parameters, and wherein the first and second approximative model differ with regard to the consideration of at least one MR parameter. The MR image is determined from a mean calculation that depends on the first and second approximated MR image.

Abstract translation: 在通过使用化学位移成像多回波MR测量序列用至少两个自旋物质确定检查对象的磁共振图像的方法和装置中，基于第一近似模型和第二近似模型确定第一近似MR图像 基于第二近似模型确定近似MR图像，其中所述第一和第二近似模型分别在考虑一个或多个MR参数的情况下表示MR信号，并且其中所述第一和第二近似模型关于至少考虑至少 一个MR参数。 根据取决于第一和第二近似MR图像的平均计算确定MR图像。

公开(公告)号：US20100052675A1

公开(公告)日：2010-03-04

申请号：US12504789

申请日：2009-07-17

Applicant: Agus Priatna ,  Stephan Kannengiesser

Inventor： Agus Priatna ,  Stephan Kannengiesser

IPC: G01R33/48

CPC classification number: G01R33/561 ,  G01R33/5613 ,  G01R33/56509

Abstract: A system uses a three-dimensional spoiled gradient recalled echo sequence for fat suppression with reduced total acquisition time suitable for acquiring image data under breath-hold conditions using a reversed asymmetry during data acquisition on an opposed phase echo. A system reduces RF pulse repetition time in an MR imaging pulse sequence in an MR imaging device. The system includes an RF pulse generator for generating an RF excitation pulse sequence having a pulse repetition interval. A read-out gradient magnetic field generator generates an asymmetric read-out gradient magnetic field having a readout gradient mid-point occurring prior to an RF echo pulse peak. The RF echo pulse peak is received in response to a generated RF excitation pulse.

Abstract translation: 系统使用三维损坏梯度回归序列进行脂肪抑制，减少总采集时间，适用于在相对相位回波数据采集期间使用逆向不对称，在呼吸保持条件下获取图像数据。 一种系统降低MR成像装置中的MR成像脉冲序列中的RF脉冲重复时间。 该系统包括用于产生具有脉冲重复间隔的RF激励脉冲序列的RF脉冲发生器。 读出梯度磁场发生器产生具有在RF回波脉冲峰值之前出现的读出梯度中点的非对称读出梯度磁场。 响应于产生的RF激励脉冲接收RF回波脉冲峰值。

公开(公告)号：US07528601B2

公开(公告)日：2009-05-05

申请号：US12022274

申请日：2008-01-30

Applicant: Hans-Peter Fautz ,  Stephan Kannengiesser

Inventor： Hans-Peter Fautz ,  Stephan Kannengiesser

IPC: G01V3/00 ,  G06K9/00 ,  G06K9/40

CPC classification number: G01R33/56545 ,  G01R33/4835 ,  G01R33/5659

Abstract: In a method and apparatus for MRT imaging, data sets acquired from magnetic resonance signals of at least two limited spatial regions of a subject to be examined, (the spatial regions being displaced relative to one another along one spatial direction and overlapping in the respective edge region. Phase coding occurs in an inhomogeneous non-edge region, likewise in this spatial direction. For at least one of these spatial regions, a modulation function is determined that is limited to this entire spatial region and modulates the subject information. Foldovers in the overlap regions of the different spatial regions are calculated on the basis of the modulation function and the MRT images of the non-edge regions of the respective spatial regions are combined without foldovers in the spatial direction under consideration of the calculated foldings.

Abstract translation: 在用于MRT成像的方法和装置中，从要检查的对象的至少两个有限空间区域的磁共振信号获取的数据集（空间区域沿着一个空间方向相对于彼此移位并且在相应边缘中重叠） 相位编码发生在不均匀的非边缘区域，同样在该空间方向上，对于这些空间区域中的至少一个，确定了限制于该整个空间区域并调制主题信息的调制函数。 基于调制函数计算不同空间区域的重叠区域，并且在考虑计算的折叠的情况下将各空间区域的非边缘区域的MRT图像在空间方向上组合而不进行叠合。

公开(公告)号：US20070085536A1

公开(公告)日：2007-04-19

申请号：US11540164

申请日：2006-09-29

Applicant: Vladimir Jellus ,  Stephan Kannengiesser ,  David Porter

Inventor： Vladimir Jellus ,  Stephan Kannengiesser ,  David Porter

IPC: G01V3/00

CPC classification number: G01R33/565 ,  G01R33/3415 ,  G01R33/5659

Abstract: In the operation of a magnetic resonance system, an RF excitation coil emits an excitation pulse such that nuclei in an examination subject are excited to emit of magnetic resonance signals. A number of local coils acquire the magnetic resonance signals emitted from the examination subject, with the magnetic resonance signals acquired by the local coils being coded in frequency space. An evaluation device accepts the magnetic resonance signals acquired by the local coils or accepts intermediate signals derived therefrom via one transmission channel per signal, and corrects the accepted signals using correction signals. The evaluation device uses the corrected signals reconstructing an image of the examination subject. The evaluation device determines the correction signals for all signals to be corrected using the same reference signal.

公开(公告)号：US07558614B2

公开(公告)日：2009-07-07

申请号：US11408552

申请日：2006-04-21

Applicant: Mark Griswold ,  Stephan Kannengiesser

Inventor： Mark Griswold ,  Stephan Kannengiesser

IPC: A61B5/05 ,  G01V3/00

CPC classification number: G01R33/5611 ,  G01R33/5612 ,  G01R33/583

Abstract: In a method for determining transmission coil-specific RF excitation pulses for component coils of a transmission coil array for accelerated, PPA-based volume-selective magnetic resonance excitation of a tissue region of a patient, and a magnetic resonance tomography apparatus operating according to the method, a first series of volume-selective RF excitation pulses along a first transmission trajectory in transmission κ-space is successively individually radiated by the component coils of the transmission coil array and the resulting magnetic resonance signals are received, and a second series of volume-selected RF excitation pulses along a further reduced transmission trajectory in transmission κ-space is simultaneously radiated by all component coils of the transmission coil array and the resulting magnetic resonance signals are received, and a complete transmission trajectory in transmission κ-space is then determined from which combination coefficients are calculated, and the coil specific RF excitation pulses are then calculated from the combination coefficients in order to produce a desired excitation profile.

Abstract translation: 在用于确定用于加速的基于PPA的体积选择性磁共振激励患者的组织区域的传输线圈阵列的分量线圈的传输线圈特定RF激励脉冲的方法中，以及根据该方法操作的磁共振断层摄影装置 方法中，沿传输线圈阵列中的第一传输轨迹的第一系列体积选择性RF激励脉冲被传输线圈阵列的分量线圈连续单独辐射，并且接收所得到的磁共振信号，并且接收第二系列体积 通过传输线圈阵列的所有分量线圈同时辐射沿着传输卡巴空间中进一步减小的传输轨迹的选择的RF激励脉冲，并且接收所得到的磁共振信号，然后确定传输卡巴空间中的完整传输轨迹 从中计算组合系数， 然后从组合系数计算线圈特定的RF激励脉冲，以便产生期望的激励曲线。

公开(公告)号：US07511489B2

公开(公告)日：2009-03-31

申请号：US11409353

申请日：2006-04-21

Applicant: Hans-Peter Fautz ,  Stephan Kannengiesser

Inventor： Hans-Peter Fautz ,  Stephan Kannengiesser

IPC: G01V3/00

CPC classification number: G01R33/56375 ,  G01R33/5611 ,  G01R33/56383

Abstract: In a method for magnetic resonance imaging on the basis of a partially-parallel acquisition (PPA) reconstruction method and a magnetic resonance tomography apparatus, data for at least two two-dimensional slices of a patient are acquired (which two-dimensional slices are displaced in the direction of a slice-selection gradient (z-gradients) defining the slice-normal direction) with at least one data acquisition in k-space (which acquisition forms a partial data set) per slice with a number of component coils, with the sum of all partial data sets forming a complete data set in k-space. The coil sensitivities of each component coil are determined on the basis of the complete data set. At least one partial data set of each slice is completed with a PPA reconstruction method on the basis of the determined coil sensitivities. The completed slices in k-space are transformed into whole images in the spatial domain.

Abstract translation: 在基于部分平行采集（PPA）重建方法和磁共振断层摄影装置的磁共振成像方法中，获取患者的至少两个二维切片的数据（该二维切片被置换 在定义切片法线方向的切片选择梯度（z-梯度）的方向上，每片具有多个分量线圈的k空间中的至少一次数据采集（其获取形成部分数据集），其中， 在k空间中形成完整数据集的所有部分数据集的总和。 根据完整的数据集确定各部件线圈的线圈灵敏度。 基于确定的线圈灵敏度，利用PPA重建方法完成每个切片的至少一个部分数据集。 在k空间中完成的切片被转换成空间域中的整个图像。

公开(公告)号：US07429862B2

公开(公告)日：2008-09-30

申请号：US11406573

申请日：2006-04-18

Applicant: Evgueni G. Kholmovski ,  Stephan Kannengiesser

Inventor： Evgueni G. Kholmovski ,  Stephan Kannengiesser

IPC: G01V3/00

CPC classification number: G01R33/5611

Abstract: In a PPA MRT method and apparatus, a selected region of k-space containing respective portions of some of the incomplete, measured data lines and respective portions of some of the complete, reconstructed data lines is designated. For each data line in the selected region, a level of the noise therein is identified. For each reconstructed, complete data line in the selected region, a scaling factor is calculated that is dependent on the noise level in that reconstructed, complete data line and the noise level in at least one neighboring incomplete, measured data line in the selected region. The scaling factor is then applied to the reconstructed, complete data line in question, so that the contribution of that line to the overall reconstructed image is adjusted according to the scaling factor. The scaling factor can be limited dependent on where the selected region is located in k-space.

Abstract translation: 在PPA MRT方法和装置中，指定包含一些不完整测量数据线的各部分的k空间的选定区域以及一些完整的重建数据线的相应部分。 对于所选区域中的每个数据线，识别其中的噪声水平。 对于所选区域中的每个重建的完整数据线，计算取决于该重建的完整数据线中的噪声电平和所选区域中的至少一个相邻不完整测量数据线中的噪声电平的缩放因子。 然后将缩放因子应用于所讨论的重建的完整数据线，使得根据缩放因子来调整该线对整个重建图像的贡献。 缩放因子可以根据所选择的区域在k空间中的位置进行限制。

公开(公告)号：US20080180099A1

公开(公告)日：2008-07-31

申请号：US12022274

申请日：2008-01-30

Applicant: Hans-Peter Fautz ,  Stephan Kannengiesser

Inventor： Hans-Peter Fautz ,  Stephan Kannengiesser

IPC: G01R33/483

CPC classification number: G01R33/56545 ,  G01R33/4835 ,  G01R33/5659

Abstract: In a method and apparatus for MRT imaging, data sets acquired from magnetic resonance signals of at least two limited spatial regions of a subject to be examined, (the spatial regions being displaced relative to one another along one spatial direction and overlapping in the respective edge region. Phase coding occurs in an inhomogeneous non-edge region, likewise in this spatial direction. For at least one of these spatial regions, a modulation function is determined that is limited to this entire spatial region and modulates the subject information. Foldovers in the overlap regions of the different spatial regions are calculated on the basis of the modulation function and the MRT images of the non-edge regions of the respective spatial regions are combined without foldovers in the spatial direction under consideration of the calculated foldings.

Abstract translation: 在用于MRT成像的方法和装置中，从要检查的对象的至少两个有限空间区域的磁共振信号获取的数据集（空间区域沿着一个空间方向相对于彼此移位并且在相应边缘中重叠） 相位编码发生在不均匀的非边缘区域，同样在该空间方向上，对于这些空间区域中的至少一个，确定了限制于该整个空间区域并调制主题信息的调制函数。 基于调制函数计算不同空间区域的重叠区域，并且在考虑计算的折叠的情况下将各空间区域的非边缘区域的MRT图像在空间方向上组合而不进行叠合。

公开(公告)号：US20080139919A1

公开(公告)日：2008-06-12

申请号：US11753691

申请日：2007-05-25

Applicant: Stephan Kannengiesser ,  Ralf Loeffler ,  Edgar Mueller ,  Peter Schmitt

Inventor： Stephan Kannengiesser ,  Ralf Loeffler ,  Edgar Mueller ,  Peter Schmitt

IPC: A61B5/055

CPC classification number: G01R33/5611 ,  G01R33/4824

Abstract: In a method as well as a magnetic resonance tomography apparatus for implementation of such a method for improved sensitivity-encoded magnetic resonance imaging using a two-dimensional or three-dimensional acquisition coil array, two-dimensional or three-dimensional undersampling of k-space is undertaken by measurement of a number N of basic partial trajectories τn in k-space that in their entirety form a geometric arrangement of source points, a number M of different operators Cm(Δ km) are determined, with each operator representing an algebraic transformation with which unmeasured target points at an interval Δ km from one of the measured source points are synthesized from a number of measured source points, the operators Cm(Δ km) are applied to at least one subset of the measured source points for at least partial completion of the magnetic resonance data set, and a largely artifact-free image is reconstructed in three-dimensional space on the basis of the measured source points and the synthesized data points.

Abstract translation: 在一种方法以及用于实施这种用于使用二维或三维采集线圈阵列改进灵敏度编码的磁共振成像的方法的磁共振断层摄影装置中，k空间的二维或三维欠采样 通过测量k空间中的N个基本部分轨迹τN n N进行，其整体形成源点的几何排列，M个不同算子C m， 确定每个运算符代表一个代数变换（Delta k m）），其中未测量的目标点的间隔距离为Δ k 从测量的源点之一中的一个m 从多个测量的源点合成，运算符C＆prime;（Delta＆lt; O OYYLE =“SINGLE” m>）被施加到测量的源点的至少一个子集，用于至少部分完成磁共振 ce数据集，并且基于测量的源点和合成数据点在三维空间中重建大量无伪影的图像。