公开(公告)号：US12092716B2

公开(公告)日：2024-09-17

申请号：US17638206

申请日：2020-08-28

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Mohammad Hossein Kadbi ,  Lizette Warner ,  Marinus Johan Kruiskamp

IPC: G01R33/56 ,  A61B5/00 ,  A61B5/055 ,  A61N5/10 ,  G01R33/48 ,  G01R33/567

CPC classification number: G01R33/5608 ,  A61B5/0036 ,  A61B5/055 ,  A61N5/1037 ,  G01R33/4812 ,  G01R33/4828 ,  G01R33/567 ,  A61N2005/1055

Abstract: Disclosed herein is a medical system (100, 300, 500) comprising a processor (104) configured for controlling the medical system and a memory (110) for storing machine executable instructions. Execution of the instructions causes the processor to receive (200) four-dimensional Dixon magnetic resonance image data (122). The four-dimensional Dixon magnetic resonance imaging data is T1 weighted. The four-dimensional Dixon magnetic resonance image data is synchronized to a respiratory signal (124). Execution of the instructions further causes the processor to reconstruct (202) synthetic four-dimensional computed tomographic image data (12) from the four-dimensional Dixon magnetic resonance imaging data. The four-dimensional Dixon magnetic resonance imaging data is synchronized to the respiratory signal.

公开(公告)号：US20240230810A1

公开(公告)日：2024-07-11

申请号：US18554397

申请日：2022-04-11

Applicant: The Regents of the University of California

Inventor： Shu-Fu Shih ,  Holden H. Wu

IPC: G01R33/56 ,  G01R33/48 ,  G06T7/00

CPC classification number: G01R33/5608 ,  G01R33/4828 ,  G06T7/0016 ,  G06T2207/20081 ,  G06T2207/20084 ,  G06T2207/30056

Abstract: A method for generating magnetic resonance imaging (MRI) quantitative parameter maps includes receiving at least one multi-contrast magnetic resonance (MR) image of a subject, providing the image to an artifact suppression deep learning network of a two-stage deep learning network and generating at least one multi-contrast MR image with suppressed undersampling artifacts using the artifact suppression deep learning network. The method further includes providing the at least one multi-contrast MR image with suppressed undersampling artifacts to a parameter mapping deep learning network of the two-stage deep learning network, generating at least one quantitative MR parameter map and generating an uncertainty estimation map for the at least one quantitative MR parameter map using the parameter mapping deep learning network. The method further includes displaying at least one multicontrast MR image with suppressed undersampling artifacts, at least one quantitative MR parameter map, and the corresponding uncertainty estimation map on a display.

公开(公告)号：US11977140B2

公开(公告)日：2024-05-07

申请号：US17807855

申请日：2022-06-20

Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.

Inventor： Hui Liu ,  Qi Liu ,  Yichen Hu

IPC: G01V3/00 ,  G01R33/24 ,  G01R33/48 ,  G01R33/485 ,  G01R33/561

CPC classification number: G01R33/485 ,  G01R33/243 ,  G01R33/4828 ,  G01R33/5616

Abstract: The present disclosure provides a system for MRI. The system may obtain a plurality of echo signals relating to a subject that are excited by an MRI pulse sequence applied to the subject. The system may perform a quantitative measurement on the subject based on the plurality of echo signals. The MRI pulse sequence may include a CEST module configured to selectively excite exchangeable protons or exchangeable molecules in the subject, an RF excitation pulse applied after the CEST module configured to excite a plurality of gradient echoes, and one or more refocusing pulses applied after the RF excitation pulse. Each of the refocusing pulses may be configured to excite one or more spin echoes. The one or more spin echoes excited by at least one of the one or more refocusing pulses may include a symmetric spin echo and one or more asymmetric spin echoes.

公开(公告)号：US20240094320A1

公开(公告)日：2024-03-21

申请号：US18275816

申请日：2022-02-08

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Holger Eggers

IPC: G01R33/48 ,  G01R33/385 ,  G01R33/50 ,  G01R33/56 ,  G01R33/565

CPC classification number: G01R33/4828 ,  G01R33/385 ,  G01R33/50 ,  G01R33/5608 ,  G01R33/56518

Abstract: The invention relates to a method of Dixon-type MR imaging. The object (10) is subjected to a dual- or multi-acquisition imaging sequence comprising a series of temporally equidistant RF pulses. An echo signal is generated in the presence of a readout magnetic field gradient in each time interval (TR) between successive RF pulses, with the echo time varying between at least a first value (TE1) associated with a first acquisition (ACQ1) and a second value (TE2) associated with a second acquisition (ACQ2). The invention proposes that at least one of the magnetic field gradients preceding and/or succeeding the readout magnetic field gradient in each time interval (TR) is temporally shifted, varied in duration and/or varied in amplitude between time intervals (TR). In this way, a reduction of the acoustic noise generated by the multi-acquisition Dixon sequence and, thus, of the discomfort for patients undergoing a corresponding examination is achieved. The echo signals are recorded and an MR image is reconstructed with separating signal contributions from water and fat based on the recorded echo signals of the at least two acquisitions (ACQ1, ACQ2). Moreover the invention relates to an MR device (1) and to a computer program to be run on an MR device (1).

公开(公告)号：US11861827B2

公开(公告)日：2024-01-02

申请号：US17168545

申请日：2021-02-05

Applicant: Siemens Healthcare GmbH

Inventor： Stephan Kannengiesser ,  Berthold Kiefer ,  Tommaso Mansi ,  Marcel Dominik Nickel ,  Thomas Pheiffer

IPC: G06K9/00 ,  G06T7/00 ,  G16H10/60 ,  G16H30/20 ,  G16H50/20 ,  A61B5/055 ,  A61B5/00 ,  G01R33/48 ,  G01R33/56 ,  G06N3/08 ,  G06N3/045

CPC classification number: G06T7/0012 ,  A61B5/055 ,  A61B5/4244 ,  A61B5/7267 ,  G01R33/4828 ,  G01R33/5608 ,  G06N3/045 ,  G06N3/08 ,  G16H10/60 ,  G16H30/20 ,  G16H50/20 ,  A61B2576/02 ,  G06T2207/10088 ,  G06T2207/20081 ,  G06T2207/20084 ,  G06T2207/30056

Abstract: The disclosure relates to techniques for automatically characterizing liver tissue of a patient, comprising receiving morphological magnetic resonance image data set and at least one magnetic resonance parameter map of an imaging region comprising at least partially the liver of the patient, each acquired by a magnetic resonance imaging device, via a first interface. The techniques further include applying a trained function comprising a neural network to input data comprising at least the image data set and the parameter map. At least one tissue score describing the liver tissue is generated as output data, which is provided using a second interface.

公开(公告)号：US11828822B2

公开(公告)日：2023-11-28

申请号：US17607774

申请日：2020-04-30

Applicant: Purdue Research Foundation

Inventor： Uzay Emir ,  Mark Chiew

IPC: G01R33/483 ,  A61B5/055 ,  G01R33/48 ,  G01R33/485

CPC classification number: G01R33/4835 ,  A61B5/055 ,  G01R33/485 ,  G01R33/4824 ,  G01R33/4828

Abstract: A method of performing magnetic resonance spectroscopic imaging (MRSI) measures neurochemical profiles over larger regions non-invasively. The method includes transmitting a multi-slice excitation pulse through tissue, the multi-slice excitation pulse configured to generate multi-slice MRSI signals. The method also includes performing density weighted concentric ring acquisition on the multi-slice MRSI signals. The method further includes receiving the generated multi-slice MRSI signals in a plurality of sensors disposed in various locations around the tissue. Imaging data is reconstructed based on the acquired imaging signals. A representation of the data is displayed.

公开(公告)号：US20230341491A1

公开(公告)日：2023-10-26

申请号：US17792408

申请日：2021-05-13

Applicant: WUXI MARVEL STONE HEALTHCARE CO., LTD.

Inventor： Hai LUO ,  Weiqian WANG ,  Xiao CHEN ,  Yue ZHAO ,  Yunhao XIE ,  Ziyue WU

IPC: G01R33/48 ,  G01R33/34 ,  G01R33/565 ,  A61B5/055

CPC classification number: G01R33/4828 ,  G01R33/34092 ,  G01R33/56563 ,  A61B5/055 ,  A61B5/704

Abstract: A comprehensive and integrated solution, including a dedicated system structure and grounding mechanism, a main radio frequency (RF) coil to transmit and receive signal, secondary RF coils to saturate unwanted signals from non-region-of-interest (ROI) in the excited region, an RF shielding structure configured to shield the main RF coil from generating signals on the non-ROI, and an environmental noise active cancellation mechanism is proposed to construct an NMR system for non-invasive quantitative detection of organs, and further improves the target region selectivity and detection accuracy.

公开(公告)号：US20230333185A1

公开(公告)日：2023-10-19

申请号：US18135990

申请日：2023-04-18

Applicant: New York University

Inventor： KAI TOBIAS BLOCK ,  Ruoxun Zi ,  Hersh Chandarana

IPC: G01R33/48

CPC classification number: G01R33/4828

Abstract: Exemplary systems, methods and computer-accessible medium according to exemplary embodiments of the present disclosure can separate fat and water in magnetic resonance imaging using frequency sweep radiofrequency saturation pulses. In an exemplary procedure, periodic RF saturation pulses with varying frequency offset from a water resonance frequency with at least two different offsets are emanated. In another exemplary procedure, the signal response to saturation at different frequencies on a voxel-by-voxel basis can be analyzed.

公开(公告)号：US11686798B2

公开(公告)日：2023-06-27

申请号：US17489698

申请日：2021-09-29

Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION

Inventor： Nathan Tibbitts Roberts

IPC: G01R33/48 ,  G01R33/485 ,  G01R33/56 ,  G01R33/565 ,  G01R33/44 ,  G01R33/385

CPC classification number: G01R33/485 ,  G01R33/385 ,  G01R33/445 ,  G01R33/4828 ,  G01R33/5608 ,  G01R33/56518 ,  G01R33/56527

Abstract: A system and method are provided for magnetic resonance imaging (MRI) and/or image reconstruction that includes acquiring multi-pass, chemical shift-encoded (CSE)-MRI imaging data of a subject. The method further includes performing a complex, joint estimation of phase terms in the imaging data for each pass of the multi-pass, CSE-MRI imaging data to account for concomitant gradient (CG)-induced phase errors of different passes. The method also includes generating at least one of a proton density fat fraction (PDFF) estimate or an R2* estimate that is unbiased by CG-induced phase errors using the phase terms and communicating a report that includes at least one of the PDFF estimate or the R2* estimate.

公开(公告)号：US20230148948A1

公开(公告)日：2023-05-18

申请号：US18090652

申请日：2022-12-29

Applicant: Livivos Inc.

Inventor： Pablo Jose Prado

IPC: A61B5/00 ,  G01R33/46 ,  A61B5/055 ,  G01R33/38 ,  G01R33/48

CPC classification number: A61B5/4244 ,  G01R33/46 ,  A61B5/055 ,  A61B5/4872 ,  G01R33/3802 ,  G01R33/3808 ,  G01R33/4828 ,  G01R33/383

Abstract: An apparatus for non-invasive evaluations and in-vivo diagnostics includes an open magnet, an RF antenna, and an NMR analytics logical circuit communicatively coupled to the RF antenna, wherein the open magnet is shaped to generate a static magnetic field that extends unilaterally into an object or internal organ of a subject when the open magnet is positioned against or in proximity to the object or subject, the static and RF magnetic fields shaped to generate a sensitive volume within a target region. The RF antenna or antenna array is configured to transmit RF pulses into the target region of the object or internal organ and receive sets of NMR signals generated by hydrogen or other elements, and the NMR analytics logical circuit is configured to obtain and analyze sets of NMR signals.