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11.发明申请Novel combinations of medicaments for the treatment of respiratory diseases containing long-acting beta-agonists and at least one additional active ingredient 审中-公开用于治疗含有长效β-激动剂和至少一种另外的活性成分的呼吸道疾病的药物的新型组合公开(公告)号：US20070037781A1
公开(公告)日：2007-02-15
申请号：US11424558
申请日：2006-06-16
IPC分类号： A61K31/56 , A61K31/538 , A61K31/517 , A61K31/498 , A61K31/4709
CPC分类号： A61K45/06 , A61K31/538 , A61K2300/00
摘要： Disclosed are medicament combinations which contain in addition to one or more, preferably one, compound of general formula 1 wherein the groups X, Ra, Rb, R1, R1′, R2, R2′, R2″, R2′″, V and n may have the meanings given in the claims and in the specification, at least one other active substance 2, processes for preparing them and their use as pharmaceutical compositions.
摘要翻译： 公开了含有一种或多种，优选一种通式1化合物的药物组合，其中基团X，R a，R b，R b， 1，R 1，R 2，R 2，R 2，R“2”， R“和”2“可以具有权利要求书和说明书中给出的含义，至少一种其它活性物质2，其制备方法及其作为药物组合物的用途。
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公开(公告)号：US20140148492A1
公开(公告)日：2014-05-29
申请号：US14082259
申请日：2013-11-18
CPC分类号： A61Q7/00 , A61K8/49 , A61K8/4946 , A61K8/69 , A61K31/4155 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/12
摘要： The present invention relates to compounds of formula (Ia) or (Ib) or pharmaceutically acceptable salts thereof for use in the treatment or prevention of hairloss, wherein Ra, Rb, Rc, Rd, Y1, Y2, Y3, Y4, Y5, Z, R1, R2, n and R3 have one of the meanings as indicated in the specification and claims, to pharmaceutical compositions containing said compounds or pharmaceutically acceptable salts thereof, to the use of said compounds or pharmaceutically acceptable salts thereof for the manufacture of a medicament useful for the treatment or prevention of hairloss, to a method of treating or preventing hairloss as well as to a method of stimulating hair growth.
摘要翻译： 本发明涉及用于治疗或预防脱发的式（Ia）或（Ib）化合物或其药学上可接受的盐，其中Ra，Rb，Rc，Rd，Y1，Y2，Y3，Y4，Y5，Z R1，R2，n和R3具有如说明书和权利要求中所述的含义之一，含有所述化合物或其药学上可接受的盐的药物组合物用于制备药物的所述化合物或其药学上可接受的盐 可用于治疗或预防脱发，治疗或预防脱发的方法以及刺激头发生长的方法。
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公开(公告)号：US20140148470A1
公开(公告)日：2014-05-29
申请号：US14082256
申请日：2013-11-18
CPC分类号： A61K8/4953 , A61K31/505 , A61K31/506 , A61Q7/00 , C07D239/42 , C07D239/48 , C07D403/06
摘要： The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof for use in the treatment or prevention of hairloss, wherein R1, R2, R3, R4, R5 and R6 have one of the meanings as indicated in the specification and claims, to pharmaceutical compositions containing said compounds or pharmaceutically acceptable salts thereof, to the use of said compounds or pharmaceutically acceptable salts thereof for the manufacture of a medicament useful for the treatment or prevention of hairloss, to a method of treating or preventing hairloss as well as to a method of stimulating hair growth.
摘要翻译： 本发明涉及用于治疗或预防脱发的式（I）化合物或其药学上可接受的盐，其中R1，R2，R3，R4，R5和R6具有说明书和权利要求书中指出的含义之一 包含所述化合物或其药学上可接受的盐的药物组合物用于所述化合物或其药学上可接受的盐在制备用于治疗或预防脱发的药物中的用途，治疗或预防脱发的方法以及 涉及一种刺激头发生长的方法。
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14.发明申请4-DIMETHYLAMINO-PHENYL-SUBSTITUTED NAPHTHYRIDINES, AND USE THEREOF AS MEDICAMENTS 有权4-二甲基苯胺基 - 取代的萘啶，并作为药物使用公开(公告)号：US20140142135A1
公开(公告)日：2014-05-22
申请号：US14071016
申请日：2013-11-04
申请人： Dennis FIEGEN , Sandra HANDSCHUH , Silke HOBBIE , Matthias HOFFMANN , Takeshi KONO , Yayoi SATO , Andreas SCHNAPP , Annette SCHULER-METZ
发明人： Dennis FIEGEN , Sandra HANDSCHUH , Silke HOBBIE , Matthias HOFFMANN , Takeshi KONO , Yayoi SATO , Andreas SCHNAPP , Annette SCHULER-METZ
IPC分类号： C07D471/04
CPC分类号： C07D471/04 , C07D519/00
摘要： The invention relates to new substituted naphthyridines of formula 1, as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates or solvates thereof, wherein R1 and R6 may have the meanings as described in claim 1, as well as medicaments which contain these compounds. Further, the invention relates to methods of treating a disease selected from asthma, COPD, allergic rhinitis, adult respiratory distress syndrome, bronchitis, allergic dermatitis, contact dermatitis, idiopathic thrombocytopenic purpura, rheumatoid arthritis and allergic rhinoconjunctivitis by administrating an appropriate amount of a compound of formula 1 to a patient in need thereof.
摘要翻译： 本发明涉及式1的新的取代的萘啶，以及其药学上可接受的盐，非对映异构体，对映异构体，外消旋体，水合物或溶剂合物，其中R 1和R 6可以具有权利要求1所述的含义，以及含有这些 化合物。 此外，本发明涉及通过施用适量的化合物治疗选自哮喘，COPD，变应性鼻炎，成人呼吸窘迫综合征，支气管炎，过敏性皮炎，接触性皮炎，特发性血小板减少性紫癜，类风湿性关节炎和过敏性鼻炎的疾病的方法 式1给有需要的患者。
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公开(公告)号：US20140148484A1
公开(公告)日：2014-05-29
申请号：US14082257
申请日：2013-11-18
CPC分类号： A61Q7/00 , A61K8/494 , A61K31/415 , C07D231/12
摘要： The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof for use in the treatment or prevention of hairloss, wherein W, L1, L2, X, L3, Y, R1 and R2 have one of the meanings as indicated in the specification and claims, to pharmaceutical compositions containing said compounds or pharmaceutically acceptable salts thereof, to the use of said compounds or pharmaceutically acceptable salts thereof for the manufacture of a medicament useful for the treatment or prevention of hairloss, to a method of treating or preventing hairloss as well as to a method of stimulating hair growth.
摘要翻译： 本发明涉及用于治疗或预防脱发的式（I）化合物或其药学上可接受的盐，其中W，L 1，L 2，X，L 3，Y，R 1和R 2具有如 说明书和权利要求书，涉及含有所述化合物或其药学上可接受的盐的药物组合物用于制备用于治疗或预防脱发的药物的所述化合物或其药学上可接受的盐，治疗或预防的方法 脱发以及刺激头发生长的方法。
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