公开(公告)号：US20100152804A1

公开(公告)日：2010-06-17

申请号：US12633893

申请日：2009-12-09

申请人： Karen J. Kleckner ,  Kathleen A. Prieve ,  Jeffrey M. Gillberg ,  Ren Zhou ,  Kenneth M. Anderson ,  D. Curtis Deno ,  Glenn C. Zillmer ,  Ruth N. Klepfer ,  Vincent E. Splett ,  David E. Euler ,  Lawrence J. Mulligan ,  Edwin G. Duffin ,  David A. Igel ,  John E. Burnes

发明人： Karen J. Kleckner ,  Kathleen A. Prieve ,  Jeffrey M. Gillberg ,  Ren Zhou ,  Kenneth M. Anderson ,  D. Curtis Deno ,  Glenn C. Zillmer ,  Ruth N. Klepfer ,  Vincent E. Splett ,  David E. Euler ,  Lawrence J. Mulligan ,  Edwin G. Duffin ,  David A. Igel ,  John E. Burnes

IPC分类号： A61N1/365

CPC分类号： A61N1/3627 ,  A61N1/36114 ,  A61N1/36521 ,  A61N1/36564 ,  A61N1/36578 ,  A61N1/36585 ,  A61N1/3684 ,  A61N1/3962

摘要： The above-described methods and apparatus are believed to be of particular benefit for patients suffering heart failure including cardiac dysfunction, chronic HF, and the like and all variants as described herein and including those known to those of skill in the art to which the invention is directed. It will understood that the present invention offers the possibility of monitoring and therapy of a wide variety of acute and chronic cardiac dysfunctions. The current invention provides systems and methods for delivering therapy for cardiac hemodynamic dysfunction via the innervated myocardial substrate receives one or more discrete pulses of electrical stimulation during the refractory period of said innervated myocardial substrate.

摘要翻译： 据信上述方法和装置对于患有心力衰竭，包括心脏功能障碍，慢性HF等的患者以及本文所述的所有变体以及包括本发明的本领域技术人员已知的那些的患者特别有益 被指示。 应当理解，本发明提供监测和治疗各种急性和慢性心脏功能障碍的可能性。 本发明提供了用于通过所述神经支配的心肌底物递送治疗心脏血液动力学功能障碍的系统和方法，在所述神经支配的心肌基质的不应期期间接收电刺激的一个或多个离散脉冲。