公开(公告)号：US08236813B2

公开(公告)日：2012-08-07

申请号：US12915982

申请日：2010-10-29

申请人： Hitoshi Ohki ,  Tooru Okayama ,  Masahiro Ikeda ,  Masahiro Ota ,  Yoshihiro Shibata ,  Toshiyuki Nakanishi ,  Yasusi Ueda ,  Nobuyuki Suzuki ,  Shinji Matuura

发明人： Hitoshi Ohki ,  Tooru Okayama ,  Masahiro Ikeda ,  Masahiro Ota ,  Yoshihiro Shibata ,  Toshiyuki Nakanishi ,  Yasusi Ueda ,  Nobuyuki Suzuki ,  Shinji Matuura

IPC分类号： C07D491/00 ,  C07D239/00 ,  C07D471/00 ,  C07D487/00 ,  A01N43/54 ,  A61K31/505

CPC分类号： A61K31/519 ,  C07D495/16

摘要： A pyrazolopyrimidine compound represented by formula (1) that inhibits the function of HSP90 as a chaperone protein and that has antitumor activity, a medicament comprising a compound represented by formula (1), a pharmaceutical composition comprising a compound represented by formula (1), and a method for treating cancer using a compound represented by formula (1).

摘要翻译： 由式（1）表示的吡唑并嘧啶化合物，其抑制HSP90作为伴侣蛋白的功能并具有抗肿瘤活性，包含式（1）表示的化合物的药物，包含式（1）表示的化合物的药物组合物， 和使用式（1）表示的化合物治疗癌症的方法。

公开(公告)号：US20060092208A1

公开(公告)日：2006-05-04

申请号：US11262981

申请日：2005-11-01

申请人： Mikio Shoki ,  Ryuji Aoki ,  Toshiyuki Nakanishi ,  Yuichiro Itoh ,  Makoto Tsujinishi

发明人： Mikio Shoki ,  Ryuji Aoki ,  Toshiyuki Nakanishi ,  Yuichiro Itoh ,  Makoto Tsujinishi

IPC分类号： B41J29/38

CPC分类号： B41J11/0095

摘要： In an ink jet printer using an ink cartridge having an ink tank for storing ink therein and a recording head for ejecting the ink stored in the ink tank as ink drops and forming an image on a recording paper sheet, the detection accuracy of a displacement detection sensor for detecting a displacement of printing position is improved while reducing manufacturing costs of the displacement detection sensor. The displacement detection sensor is comprised of a light emitting device for emitting diffused light, a first lens for focusing the light emitted from the light emitting device on a recording paper sheet, a second lens for focusing the light reflected by the recording paper sheet and a light receiving device for receiving the light focused by the second lens. By focusing the diffused light emitted from the light emitting device by the first lens, the diameter of a beam spot projected on the recording paper sheet is made smaller than a longitudinal dimension and a width dimension of each component forming a displacement detection pattern.

摘要翻译： 在使用具有用于储存墨水的墨水盒的墨盒的喷墨打印机和用于将存储在墨水盒中的墨水作为墨滴喷射并在记录纸上形成图像的记录头的位置检测的检测精度 用于检测打印位置的位移的传感器被提高，同时降低位移检测传感器的制造成本。 位移检测传感器包括用于发射漫射光的发光装置，用于将从发光装置发射的光聚焦在记录纸上的第一透镜，用于聚焦由记录纸张反射的光的第二透镜和 用于接收由第二透镜聚焦的光的光接收装置。 通过聚焦通过第一透镜从发光器件发射的漫射光，使得突出在记录纸上的光束点的直径小于形成位移检测图案的每个部件的纵向尺寸和宽度尺寸。

公开(公告)号：US08971427B2

公开(公告)日：2015-03-03

申请号：US13553047

申请日：2012-07-19

申请人： Koji Akita ,  Takahiro Sekiguchi ,  Toshiyuki Nakanishi

发明人： Koji Akita ,  Takahiro Sekiguchi ,  Toshiyuki Nakanishi

IPC分类号： H04L27/28 ,  H04L27/26

CPC分类号： H04L27/2657 ,  H04L27/2671 ,  H04L27/2675

摘要： According to one embodiment, a wireless transceiver system includes a transmitter and a receiver. The transmitter includes a first generator, a second generator, a third generator. The second generator generates fixed data item that has bit values corresponding to the clock signal. The third generator performs OFDM modulation for the fixed data item. The receiver includes a first detector, a second detector, a PLL, a controller. The first detector is configured to detect an envelope that indicates amplitude in a time waveform. The controller is configured to control to operate the PLL from a first time point when the head part is detected to a second time point when a first period is elapsed.

摘要翻译： 根据一个实施例，无线收发器系统包括发射机和接收机。 发射机包括第一发生器，第二发生器，第三发生器。 第二生成器生成具有对应于时钟信号的位值的固定数据项。 第三发生器对固定数据项执行OFDM调制。 接收机包括第一检测器，第二检测器，PLL，控制器。 第一检测器被配置为检测指示时间波形中的振幅的包络。 所述控制器被配置为当经过第一时间段时，从头部被检测到第一时间点的第一时间点来控制所述PLL的操作。

公开(公告)号：US08947091B2

公开(公告)日：2015-02-03

申请号：US12915471

申请日：2010-10-29

申请人： Toshiyuki Nakanishi ,  Koji Akita ,  Takahiro Sekiguchi ,  Kazuya Okamoto ,  Sojuro Kato

发明人： Toshiyuki Nakanishi ,  Koji Akita ,  Takahiro Sekiguchi ,  Kazuya Okamoto ,  Sojuro Kato

IPC分类号： G01R33/36

CPC分类号： G01R33/3692 ,  G01R33/3621

摘要： According to one embodiment, an MRI apparatus includes a probe unit and a control/imaging unit. The probe unit includes a probe, a converter, a compressor and a transmitter. The control/imaging unit includes a receiver, an expander and a reconstructor. The probe detects an RF echo signal generated in a subject by a magnetic resonance phenomenon. The converter digitizes the detected signal. The compressor compresses the digitized signal in accordance with a predetermined compression parameter to obtain a compressed signal. The transmitter generates a transmission signal to wirelessly transmit the compressed echo signal and sends the transmission signal to a radio channel. The receiver receives the transmission signal and extracts the compressed signal from the received signal. The expander expands the extracted compressed signal in accordance with the parameter to obtain the RF echo signal. The reconstructor generates a video signal regarding the subject on the basis of the obtained signal.

摘要翻译： 根据一个实施例，MRI装置包括探针单元和控制/成像单元。 探头单元包括探头，转换器，压缩器和发射器。 控制/成像单元包括接收器，扩展器和重建器。 探头通过磁共振现象来检测被检体内产生的RF回波信号。 转换器将检测到的信号数字化。 压缩机根据预定的压缩参数压缩数字化信号以获得压缩信号。 发射机产生一个传输信号以无线传输压缩的回波信号，并将传输信号发送到无线电信道。 接收机接收发送信号并从接收信号中提取压缩信号。 扩展器根据参数扩展提取的压缩信号以获得RF回波信号。 重建器根据获得的信号产生关于被摄体的视频信号。

公开(公告)号：US20110227574A1

公开(公告)日：2011-09-22

申请号：US13048343

申请日：2011-03-15

申请人： Koji Akita ,  Takahiro Sekiguchi ,  Toshiyuki Nakanishi ,  Kazuya Okamoto ,  Sojuro Kato

发明人： Koji Akita ,  Takahiro Sekiguchi ,  Toshiyuki Nakanishi ,  Kazuya Okamoto ,  Sojuro Kato

IPC分类号： G01R33/20

CPC分类号： G01R33/3692 ,  G01R33/3621

摘要： In one embodiment, an MRI apparatus includes first and second clock generators, a pulse generator, transmission and reception coils, pulse and phase detectors, and a corrector. The pulse generator generates an excitation pulse signal based on a clock signal generated by the first clock generator. The reception coil outputs a radio frequency signals corresponding to an excitation pulse transmitted from the transmission coil or an MR echo. The converter digitizes, synchronously with a clock signal generated by the second clock generator, the radio frequency signal, to obtain radio frequency data. The pulse detector detects excitation pulse data corresponding to the excitation pulse from the radio frequency data. The phase detector detects a phase of a pulse indicated by the detected excitation pulse data. The corrector corrects the radio frequency data based on the detected phase, to compensate for a phase offset which occurs in the echo during the digitization.

摘要翻译： 在一个实施例中，MRI装置包括第一和第二时钟发生器，脉冲发生器，发射和接收线圈，脉冲和相位检测器以及校正器。 脉冲发生器基于由第一时钟发生器产生的时钟信号产生激励脉冲信号。 接收线圈输出与从发送线圈发送的激励脉冲或MR回波对应的射频信号。 该转换器与由第二时钟发生器产生的时钟信号，射频信号同步地数字化，以获得射频数据。 脉冲检测器从射频数据检测与激励脉冲对应的激励脉冲数据。 相位检测器检测由检测到的激励脉冲数据指示的脉冲的相位。 校正器基于检测到的相位来校正射频数据，以补偿在数字化期间在回波中发生的相位偏移。

公开(公告)号：US20110071170A1

公开(公告)日：2011-03-24

申请号：US12915982

申请日：2010-10-29

申请人： Hitoshi Ohki ,  Tooru Okayama ,  Masahiro Ikeda ,  Masahiro Ota ,  Yoshihiro Shibata ,  Toshiyuki Nakanishi ,  Yasusi Ueda ,  Nobuyuki Suzuki ,  Shinji Matuura

发明人： Hitoshi Ohki ,  Tooru Okayama ,  Masahiro Ikeda ,  Masahiro Ota ,  Yoshihiro Shibata ,  Toshiyuki Nakanishi ,  Yasusi Ueda ,  Nobuyuki Suzuki ,  Shinji Matuura

IPC分类号： A61K31/519 ,  C07D495/16 ,  A61P35/00

CPC分类号： A61K31/519 ,  C07D495/16

摘要： A pyrazolopyrimidine compound represented by formula (1) that inhibits the function of HSP90 as a chaperone protein and that has antitumor activity, a medicament comprising a compound represented by formula (1), a pharmaceutical composition comprising a compound represented by formula (1), and a method for treating cancer using a compound represented by formula (1).

摘要翻译： 由式（1）表示的吡唑并嘧啶化合物，其抑制HSP90作为伴侣蛋白的功能并具有抗肿瘤活性，包含式（1）表示的化合物的药物，包含式（1）表示的化合物的药物组合物， 和使用式（1）表示的化合物治疗癌症的方法。

公开(公告)号：US07384117B2

公开(公告)日：2008-06-10

申请号：US11262981

申请日：2005-11-01

申请人： Mikio Shoki ,  Ryuji Aoki ,  Toshiyuki Nakanishi ,  Yuichiro Itoh ,  Makoto Tsujinishi

发明人： Mikio Shoki ,  Ryuji Aoki ,  Toshiyuki Nakanishi ,  Yuichiro Itoh ,  Makoto Tsujinishi

IPC分类号： B41J29/393

CPC分类号： B41J11/0095

摘要： In an ink jet printer using an ink cartridge having an ink tank for storing ink therein and a recording head for ejecting the ink stored in the ink tank as ink drops and forming an image on a recording paper sheet, the detection accuracy of a displacement detection sensor for detecting a displacement of printing position is improved while reducing manufacturing costs of the displacement detection sensor. The displacement detection sensor is comprised of a light emitting device for emitting diffused light, a first lens for focusing the light emitted from the light emitting device on a recording paper sheet, a second lens for focusing the light reflected by the recording paper sheet and a light receiving device for receiving the light focused by the second lens. By focusing the diffused light emitted from the light emitting device by the first lens, the diameter of a beam spot projected on the recording paper sheet is made smaller than a longitudinal dimension and a width dimension of each component forming a displacement detection pattern.

摘要翻译： 在使用具有用于储存墨水的墨水盒的墨盒的喷墨打印机和用于将存储在墨水盒中的墨水作为墨滴喷射并在记录纸上形成图像的记录头的位置检测的检测精度 用于检测打印位置的位移的传感器被提高，同时降低位移检测传感器的制造成本。 位移检测传感器包括用于发射漫射光的发光装置，用于将从发光装置发射的光聚焦在记录纸上的第一透镜，用于聚焦由记录纸张反射的光的第二透镜和 用于接收由第二透镜聚焦的光的光接收装置。 通过聚焦通过第一透镜从发光器件发射的漫射光，使得突出在记录纸上的光束点的直径小于形成位移检测图案的每个部件的纵向尺寸和宽度尺寸。

公开(公告)号：US20120202833A1

公开(公告)日：2012-08-09

申请号：US13452665

申请日：2012-04-20

申请人： Hitoshi Ohki ,  Tooru Okayama ,  Masahiro Ikeda ,  Masahiro Ota ,  Yoshihiro Shibata ,  Toshiyuki Nakanishi ,  Yasusi Ueda ,  Nobuyuki Suzuki ,  Shinji Matuura

发明人： Hitoshi Ohki ,  Tooru Okayama ,  Masahiro Ikeda ,  Masahiro Ota ,  Yoshihiro Shibata ,  Toshiyuki Nakanishi ,  Yasusi Ueda ,  Nobuyuki Suzuki ,  Shinji Matuura

IPC分类号： A61K31/519 ,  A61P35/00

CPC分类号： A61K31/519 ,  C07D495/16

摘要： A pyrazolopyrimidine compound represented by formula (1) that inhibits the function of HSP90 as a chaperone protein and that has antitumor activity, a medicament comprising a compound represented by formula (1), a pharmaceutical composition comprising a compound represented by formula (1), and a method for treating cancer using a compound represented by formula (1).

摘要翻译： 由式（1）表示的吡唑并嘧啶化合物，其抑制HSP90作为伴侣蛋白的功能并具有抗肿瘤活性，包含式（1）表示的化合物的药物，包含式（1）表示的化合物的药物组合物， 和使用式（1）表示的化合物治疗癌症的方法。

公开(公告)号：US20110227571A1

公开(公告)日：2011-09-22

申请号：US13048314

申请日：2011-03-15

申请人： Takahiro Sekiguchi ,  Koji Akita ,  Toshiyuki Nakanishi ,  Kazuya Okamoto ,  Sojuro Kato

发明人： Takahiro Sekiguchi ,  Koji Akita ,  Toshiyuki Nakanishi ,  Kazuya Okamoto ,  Sojuro Kato

IPC分类号： G01R33/44

CPC分类号： G01R33/3692 ,  G01R33/3607

摘要： According to one embodiment, a apparatus includes a coil, a clock generator, an echo transmitter, a carrier generator, a clock transmitter, a regenerator, an receiver, a reconstructor, a detector, and a controller. The echo transmitter generates and transmits an echo transmission signal synchronously with a clock signal generated by the clock generator to wirelessly transmit an echo signal output from the col. The carrier generator generates a carrier signal have a frequency within a variable range. The clock transmitter wirelessly transmits a clock transmission signal. The regenerator regenerates the clock signal based on the transmitted clock transmission signal. The receiver extracts the echo signal synchronously with the regenerated clock signal from the transmitted echo transmission signal. The detector detects a frequency of an interference wave. The controller controls the carrier generator to generate the carrier signal having a frequency which comparatively small interference with respect to the detected frequency.

摘要翻译： 根据一个实施例，一种装置包括线圈，时钟发生器，回波发射器，载波发生器，时钟发射器，再生器，接收器，重建器，检测器和控制器。 回波发射机与由时钟发生器产生的时钟信号同步地生成和发送回波发送信号，以无线地发送从该列输出的回波信号。 载波发生器产生具有可变范围内的频率的载波信号。 时钟发射机无线传输时钟传输信号。 再生器基于发送的时钟传输信号再生时钟信号。 接收机从发送的回波发送信号中与再生的时钟信号同步地提取回波信号。 检测器检测到干扰波的频率。 控制器控制载波发生器以产生具有相对于检测到的频率具有相对小的干扰的频率的载波信号。

公开(公告)号：US20100054838A1

公开(公告)日：2010-03-04

申请号：US12549802

申请日：2009-08-28

申请人： Toshiyuki Nakanishi ,  Makoto Hashimoto

发明人： Toshiyuki Nakanishi ,  Makoto Hashimoto

IPC分类号： B41J15/00

CPC分类号： B41J13/0009

摘要： A printing apparatus that feeds a printing medium to a printing position and executes a printing processing is provided. In the printing apparatus, a paper feed operation performed when the rear end of the printing medium is positioned in the vicinity of a paper feed roller can be conducted accurately without hindering the printing operation. The printing apparatus that feeds a printing medium to a printing position and executes a printing processing, includes: a conveying unit that performs conveying of the printing medium including the paper feed operation and that has a paper feed roller provided before a position in which the printing processing is performed in the conveying direction; and a control unit that controls the printing processing and the conveying processing.

摘要翻译： 提供了一种将打印介质馈送到打印位置并执行打印处理的打印设备。 在打印装置中，当打印介质的后端位于送纸辊附近时执行的进纸操作可以精确地进行，而不会妨碍打印操作。 将打印介质供给到打印位置并执行打印处理的打印设备包括：输送单元，其执行包括进纸操作的打印介质的传送，并且具有设置在打印位置之前的供纸辊的输送单元 在输送方向进行处理; 以及控制打印处理和传送处理的控制单元。