专利检索 ap:("VALO EARLY DISCOVERY, INC.") AND inv:"Stephanos Ioannidis" 第 2 页

11.

发明授权
Thienopyrimidinones as ubiquitin-specific protease 7 inhibitors 有权

公开(公告)号：US10906916B2

公开(公告)日：2021-02-02

申请号：US16515194

申请日：2019-07-18

申请人： Valo Early Discovery, Inc.

发明人： Stephanos Ioannidis , Adam Charles Talbot , Bruce Follows , Alexandre Joseph Buckmelter , Minghua Wang , Ann-Marie Campbell , David R. Lancia, Jr.

IPC分类号： C07D495/04 , A61K31/519

摘要： The disclosure relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula: where R1, R2, R3, R5, R5′, X1, X2, n, and m are described herein.