Sample manager, system and method
    12.
    发明授权

    公开(公告)号:US11879875B2

    公开(公告)日:2024-01-23

    申请号:US17203021

    申请日:2021-03-16

    CPC classification number: G01N30/16 G01N35/1095 G01N2035/1027

    Abstract: A liquid chromatography sample manager includes a sampling mechanism; a sample platter mounted in the sampling mechanism, the sample platter configured to rotate about a first vertical axis; a needle arm mounted within the sampling mechanism, the needle arm configured to rotate about a second vertical axis; and a sample delivery system in fluidic communication with solvent delivery system, the sample delivery system including a sample needle attached to the needle arm, the sample delivery system configured to transfer a first sample from a first sample vial carrier located in the sample platter into a chromatographic flow stream.

    Liquid chromatography thermal system with thermal status detection

    公开(公告)号:US11555804B2

    公开(公告)日:2023-01-17

    申请号:US16516888

    申请日:2019-07-19

    Abstract: A liquid chromatography system including a solvent delivery system, a sample delivery system in fluidic communication with solvent delivery system, a liquid chromatography column located downstream from the solvent delivery system and the sample delivery system, a detector located downstream from the liquid chromatography column, a thermal chamber housing at least one of the solvent delivery system, the sample delivery system, the liquid chromatography column and the detector, an engine configured to control the temperature in the thermal chamber, a heatsink operably connected to the engine, a first temperature sensor in the thermal chamber, a second temperature sensor, and a computer system configured to receive temperature information from each of the first and second temperature sensors, and implement a method for controlling temperature in the thermal chamber.

    METERING PUMP FOR LIQUID CHROMATOGRAPHY

    公开(公告)号:US20210302397A1

    公开(公告)日:2021-09-30

    申请号:US17212329

    申请日:2021-03-25

    Abstract: Described is a metering pump that may be used to meter volumes of sample in a chromatography system. The metering pump has a modular configuration that allows for separation of a head pod from a drive assembly for easy serviceability. The head pod includes a pump head, cartridge housing, seal wash housing and plunger. The drive assembly can be implemented in an inline drive configuration. Alternatively, the drive assembly can be implemented in an offset drive configuration in which a stepper motor is displaced laterally from other drive assembly components but is coupled through a belt and pulley system.

    NEEDLE DRIVE, SYSTEM AND METHOD
    15.
    发明申请

    公开(公告)号:US20210293762A1

    公开(公告)日:2021-09-23

    申请号:US17203127

    申请日:2021-03-16

    Abstract: A liquid chromatography sample manager includes a thermal chamber, a sample platter mounted in the thermal chamber, and a needle drive including a base having a shaft configured to rotate about a vertical axis, the base attachable to an interior of a sample manager of a liquid chromatography system. The needle drive further includes a needle assembly attached to the base, the needle assembly including a sample needle, and a drive system attached to the base, the drive system including a sample needle motor configured to impart vertical movement of the sample needle. The liquid chromatography sample manager further includes a sample delivery system configured to transfer a first sample from a first sample vial carrier located in the sample platter into a chromatographic flow stream.

    SAMPLE MANAGER, SYSTEM AND METHOD
    16.
    发明申请

    公开(公告)号:US20210293761A1

    公开(公告)日:2021-09-23

    申请号:US17203021

    申请日:2021-03-16

    Abstract: A liquid chromatography sample manager includes a sampling mechanism; a sample platter mounted in the sampling mechanism, the sample platter configured to rotate about a first vertical axis; a needle arm mounted within the sampling mechanism, the needle arm configured to rotate about a second vertical axis; and a sample delivery system in fluidic communication with solvent delivery system, the sample delivery system including a sample needle attached to the needle arm, the sample delivery system configured to transfer a first sample from a first sample vial carrier located in the sample platter into a chromatographic flow stream.

    Sample organizer, tray, system and method

    公开(公告)号:US11002713B2

    公开(公告)日:2021-05-11

    申请号:US16438798

    申请日:2019-06-12

    Abstract: A liquid chromatography sample organizer includes a first chamber, a plurality of stacked sample organizer shelves mounted within the first chamber each individually configured to store a sample-vial carrier including a sample, and a shelf magnet affixed to a surface of each of the plurality of stacked sample organizer shelves. A portion of the first chamber is configured to be located adjacent to, and open to, a sample manager configured to inject liquid chromatography samples into a chromatographic flow stream. Disclosed further is a liquid chromatography system having the sample organizer, a sample drawer, and a method of transferring samples between a sample manager and the sample organizer.

    LIQUID CHROMATOGRAPHY THERMAL SYSTEM WITH THERMAL STATUS DETECTION

    公开(公告)号:US20200025724A1

    公开(公告)日:2020-01-23

    申请号:US16516888

    申请日:2019-07-19

    Abstract: A liquid chromatography system including a solvent delivery system, a sample delivery system in fluidic communication with solvent delivery system, a liquid chromatography column located downstream from the solvent delivery system and the sample delivery system, a detector located downstream from the liquid chromatography column, a thermal chamber housing at least one of the solvent delivery system, the sample delivery system, the liquid chromatography column and the detector, an engine configured to control the temperature in the thermal chamber, a heatsink operably connected to the engine, a first temperature sensor in the thermal chamber, a second temperature sensor, and a computer system configured to receive temperature information from each of the first and second temperature sensors, and implement a method for controlling temperature in the thermal chamber.

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