公开(公告)号：US07441900B2

公开(公告)日：2008-10-28

申请号：US10467159

申请日：2002-02-07

申请人： Toshifumi Mihashi ,  Yoko Hirohara

发明人： Toshifumi Mihashi ,  Yoko Hirohara

IPC分类号： A61B3/02

CPC分类号： A61B3/022 ,  A61B3/032 ,  A61B3/112

摘要： A contrast chart device of the present invention comprises a contrast target presenting part for presenting a contrast target for a contrast sensitivity test at prescribed timing; a pupil data measuring part for producing an image of an anterior ocular segment of a subject and measuring the diameter or area of a pupil region in the anterior ocular segment; and a measurement timing forming part for forming timing at which the pupil data measuring part performs measurement.

摘要翻译： 本发明的对比图装置包括对比度目标呈现部分，用于在规定的时刻呈现对比度敏感度测试的对比度目标; 瞳孔数据测量部分，用于产生对象的前眼部分的图像，并测量前眼部的瞳孔区域的直径或面积; 以及用于形成瞳孔数据测量部进行测量的定时的测量定时形成部。

公开(公告)号：US20080007691A1

公开(公告)日：2008-01-10

申请号：US11812079

申请日：2007-06-14

申请人： Toshifumi Mihashi ,  Yoko Hirohara

发明人： Toshifumi Mihashi ,  Yoko Hirohara

IPC分类号： A61B3/14

CPC分类号： A61B3/10 ,  A61B3/0025 ,  G06T7/33 ,  G06T2207/30041

摘要： To provide a spectroscopic fundus measuring apparatus capable of identifying each part in spectral fundus images easily and accurately based on its spectral characteristic and a measuring method therefor. A spectral fundus image measuring apparatus 1 of the present invention includes: an illumination optical system 10; a light receiving optical system 20 for photographing a series of spectral fundus images of different wavelengths; an image processing section 7 for processing the spectral fundus images; a storage section 7A; and a display section 7B. The image processing section 7 has a position correcting section 72 for correcting the series of spectral fundus images to match the positions of the same parts therein, and an image analyzing section 73 for calculating the spectral characteristic of each part in the spectral fundus images based on the series of spectral fundus images corrected in the position correcting section 72. The storage section 7A stores the spectral characteristics of the parts together with standard spectral characteristics of specific parts. The image processing section 7 has a first grouping section 74A for comparing the spectral characteristic of each part with the standard spectral characteristics of the specific parts to divide the parts into groups corresponding to the specific parts.

摘要翻译： 提供一种能够基于其光谱特性容易且准确地识别光谱眼底图像中的每个部分的光谱眼底测量装置及其测量方法。 本发明的光谱眼底图像测量装置1包括：照明光学系统10; 用于拍摄不同波长的一系列光谱眼底图像的光接收光学系统20; 用于处理光谱眼底图像的图像处理部分7; 存储部分7A; 以及显示部分7 B.图像处理部分7具有位置校正部分72，用于校正一系列光谱眼底图像以匹配其中相同部分的位置;以及图像分析部分73，用于计算各部分的光谱特性 在基于在位置校正部分72中校正的一系列光谱眼底图像的光谱眼底图像中。存储部分7A将这些部分的光谱特性与特定部分的标准光谱特性一起存储。 图像处理部分7具有第一分组部分74A，用于将各部分的光谱特性与特定部分的标准光谱特征进行比较，以将部分划分成与特定部分相对应的组。

公开(公告)号：US20070229760A1

公开(公告)日：2007-10-04

申请号：US11723624

申请日：2007-03-21

申请人： Yoko Hirohara ,  Toshifumi Mihashi

发明人： Yoko Hirohara ,  Toshifumi Mihashi

IPC分类号： A61B3/14

CPC分类号： A61B3/101

摘要： A subject is placed in a more natural state or is encouraged to blink at specified intervals to obtain a measurement result under a fixed condition, and the judgment of the degree of dry eye is facilitated. A measurement part obtains, based on a reflected light flux from a subject eye, optical characteristic data of a two-dimensional vector form representing the time course of each optical characteristic of the subject eye in an blink interval from a certain blink to a next blink with respect to the first to the nth blink intervals. An analysis part one-dimensionally arranges each of the optical characteristic data with respect to the first to the nth blink intervals measured by the measurement part, and arranges the one-dimensional arrangement of the optical characteristic in a p-th blink interval at a p column to create a two-dimensional array, and performs a principal component analysis processing on the two-dimensional array.

摘要翻译： 受试者处于更自然的状态，或鼓励以规定的间隔眨眼以在固定条件下获得测量结果，并且便于对干眼度的判断。 测量部件基于来自被检眼的反射光通量，从在特定的闪烁到下一次闪烁的眨眼间隔中获得表示被检眼的每个光学特性的时间过程的二维矢量形状的光学特性数据 相对于第一到第n个闪烁间隔。 分析部分对由测量部分测量的第一至第N闪烁间隔的每个光学特性数据进行一维排列，并将光学特性的一维布置在第p个闪烁间隔中排列在ap列 创建二维阵列，并对二维​​阵列进行主成分分析处理。

公开(公告)号：US07241012B2

公开(公告)日：2007-07-10

申请号：US10758285

申请日：2004-01-16

申请人： Toshifumi Mihashi ,  Yoko Hirohara ,  Teruhito Kuroda ,  Naoyuki Maeda ,  Takashi Fujikado

发明人： Toshifumi Mihashi ,  Yoko Hirohara ,  Teruhito Kuroda ,  Naoyuki Maeda ,  Takashi Fujikado

IPC分类号： A61B3/10 ,  A61B3/00

CPC分类号： A61B3/101

摘要： There is provided an ophthalmologic apparatus which can be effectively used for the clinic of a dry eye by using, as a basic principle, that when a tear film dries up, a corneal shape is changed and/or a wavefront aberration becomes large. When a measurement is started, the ophthalmologic apparatus is aligned. An arithmetic part performs an initial setting of a measurement interval of the apparatus, a measurement time and the like by a wavefront measurement part. An input part or the arithmetic part triggers a measurement start, and the arithmetic part repeats a measurement of the corneal shape and corneal wavefront aberrations by a measurement part until time reaches a measurement end time. When the time reaches the measurement end time, a judgment part analyzes a breakup state as one index for judgment of a state of a dry eye. The judgment part obtains values relating to the breakup to output them, and performs an automatic diagnosis about dry eye on the basis of the values.

摘要翻译： 作为基本原理，提供了一种可以有效地用于干眼症的眼科装置，当泪膜干燥时，改变角膜形状和/或波前像差变大。 当测量开始时，眼科装置对准。 算术部通过波阵面测量部进行装置的测定间隔，测定时间等的初始设定。 输入部分或算术部分触发测量开始，并且运算部分重复通过测量部分的角膜形状和角膜波前像差的测量，直到时间到达测量结束时间。 当时间到达测量结束时间时，判断部件将分解状态分析为用于判断干眼状态的一个指标。 判断部分获得与分解相关的值以输出它们，并且基于该值来执行关于干眼症的自动诊断。

公开(公告)号：US20050073647A1

公开(公告)日：2005-04-07

申请号：US10488790

申请日：2002-08-09

申请人： Toshifumi Mihashi ,  Yoko Hirohara ,  Takashi Fujikado ,  Naoyuki Maeda

发明人： Toshifumi Mihashi ,  Yoko Hirohara ,  Takashi Fujikado ,  Naoyuki Maeda

IPC分类号： A61B3/103 ,  A61B3/00

CPC分类号： A61B3/1015 ,  A61B3/10

摘要： Scattering can be measured by using an optical system having a Hartman-Shack wave-surface sensor. An eye optical characteristic measuring instrument comprises a light source unit (10) for emitting a light beam of a wavelength in the near-infrared region, an illumination optical system (40) for illuminating a small area of the retinal of an eye to be measured with the light beam from the light

摘要翻译： 可以通过使用具有Hartman-Shack波表面传感器的光学系统来测量散射。 一种眼睛光学特性测量仪器，包括用于发射近红外区域的波长的光束的光源单元（10），用于照射待测眼睛的视网膜的小区域的照明光学系统（40） 来自光的光束

公开(公告)号：US06536900B2

公开(公告)日：2003-03-25

申请号：US09819354

申请日：2001-03-28

申请人： Toshifumi Mihashi ,  Yoko Hirohara

发明人： Toshifumi Mihashi ,  Yoko Hirohara

IPC分类号： A61B310

CPC分类号： A61B3/1015

摘要： The present invention is intended to provide an eye characteristic measuring apparatus having a projection system for projecting a light source image of small amount onto a fundus of an eye by a reflected light from the fundus, and a wavefront detecting system for detecting a wavefront of luminous flux emitted from the interior of the pupil of the eye by a reflected light from the fundus, where the projection system projects a light source image of small amount onto a fundus of an eye, and the wavefront detection system detects the wavefront of luminous flux emitted from the interior of the fundus by a reflected light from the fundus, and a deflection prism having at least one transmission surface for aberration correction within both optical paths of the projecting system and the wavefront detecting system, can deflect the incident luminous flux.

摘要翻译： 本发明旨在提供一种眼睛特征测量装置，其具有投影系统，用于通过来自眼底的反射光将少量的光源图像投射到眼底，以及用于检测发光的波前的波前检测系统 通过来自眼底的反射光从眼睛的瞳孔内部发射的光束，其中投影系统将少量的光源图像投射到眼底，并且波前检测系统检测发射的光通量的波前 从眼底的内部通过来自眼底的反射光，以及在投影系统和波阵面检测系统的两个光路内具有用于像差校正的至少一个透射面的偏转棱镜，可偏转入射光通量。

公开(公告)号：US07311402B2

公开(公告)日：2007-12-25

申请号：US10488790

申请日：2002-08-09

申请人： Toshifumi Mihashi ,  Yoko Hirohara ,  Takashi Fujikado ,  Naoyuki Maeda

发明人： Toshifumi Mihashi ,  Yoko Hirohara ,  Takashi Fujikado ,  Naoyuki Maeda

IPC分类号： A61B3/10

CPC分类号： A61B3/1015 ,  A61B3/10

摘要： Scattering can be measured by using an optical system having a Hartman-Shack wave-surface sensor. An eye optical characteristic measuring instrument comprises a light source unit 10 for emitting a light beam of a wavelength in the near-infrared region, an illumination optical system 40 for illuminating a small area of the retinal of an eye to be measured with the light beam from the light source unit 10, a light-receiving optical system 20 for receiving a part of the reflected beam of the light beam from the light source unit 10 reflected from the retina through a converting member for converting the part of the reflected light beam into at least substantially 17 light beams, a light-receiving section 23 for receiving the received light beam directed by the light-receiving optical system 20 and generating a signal, and a calculating unit for determining the wavefront aberration of the light beam entering the light-receiving optical system 20 and the degree of scattering of the received light beam on the basis of the signal from the light-receiving section 23.

摘要翻译： 可以通过使用具有Hartman-Shack波表面传感器的光学系统来测量散射。 眼睛光学特性测量仪器包括用于发射近红外区域的波长的光束的光源单元10，用于用光束照射待测眼睛的视网膜的小区域的照明光学系统40 来自光源单元10的光接收光学系统20，用于接收来自光源单元10的光束的反射光束的一部分，该光源单元10从视网膜反射通过转换部件，用于将部分反射光束转换成 至少基本上17个光束，用于接收由光接收光学系统20引导的接收光束并产生信号的光接收部分23，以及用于确定进入发光装置的光束的波前像差的计算单元， 基于来自光接收部23的信号，接收光学系统20和接收光束的散射程度。

公开(公告)号：US07216980B2

公开(公告)日：2007-05-15

申请号：US10470737

申请日：2002-02-08

申请人： Toshifumi Mihashi ,  Yoko Hirohara

发明人： Toshifumi Mihashi ,  Yoko Hirohara

IPC分类号： A61B3/10

CPC分类号： A61B3/1015 ,  A61B3/107

摘要： The aberration and refraction power data of an eye to be examined obtained from a first light reception unit and cornea data of the eye to be examined are correlated with each other so as to be overlaid accurately. A first signal and a second signal are concurrently captured, and the optical characteristics and cornea shape of the eye to be examined are measured concurrently or almost concurrently. A measuring unit (111) measures dioptrical characteristics based on a first light reception signal from the first light reception unit (23), and measures a corneal topography based on a second light reception signal from the second light reception unit (35). A coordinates setting unit (112) converts signal in first and second coordinate systems, corresponding to the eye to be examined, included in the first and second reception signal into signal in reference coordinate systems respectively. A conversion unit (116) synthesizes the first and second optical characteristics of the eye to be examined obtained by the measuring unit (111) in association with each reference coordinate system formed by the coordinates setting unit (112). A measuring timing determining unit (117) determines the measuring timing of the first signal and the second signal to be subjected to measuring operation based on the first and/or second signal.

摘要翻译： 从第一光接收单元获得的被检查眼睛的像差和折射能量数据和要检查的眼睛的角膜数据彼此相关，以便被准确地重叠。 同时捕获第一信号和第二信号，同时或几乎同时测量要检查的眼睛的光学特性和角膜形状。 测量单元（111）基于来自第一光接收单元（23）的第一光接收信号测量透光特性，并且基于来自第二光接收单元（35）的第二光接收信号测量角膜形貌。 坐标设置单元（112）分别将包括在第一和第二接收信号中的对应于被检查眼睛的第一和第二坐标系中的信号转换为参考坐标系中的信号。 转换单元（116）与由坐标设置单元（112）形成的每个参考坐标系相关联地合成由测量单元（111）获得的要检查的眼睛的第一和第二光学特性。 测量定时确定单元（117）基于第一和/或第二信号来确定要进行测量操作的第一信号和第二信号的测量定时。

公开(公告)号：US20050270484A1

公开(公告)日：2005-12-08

申请号：US10525540

申请日：2003-08-13

申请人： Naoyuki Maeda ,  Yoko Hirohara ,  Toshifumi Mihashi

发明人： Naoyuki Maeda ,  Yoko Hirohara ,  Toshifumi Mihashi

IPC分类号： A61B3/14 ,  A61B3/10

CPC分类号： A61B3/185 ,  A61B3/10 ,  A61B3/107 ,  A61B3/1208 ,  A61B3/14 ,  A61B3/152

摘要： A portable ophthmic apparatus (1) according to the present invention comprises a supporting part (7) to which a cellular phone (2) having a photographing camera (5) is mounted detachably and a main body (6) which is provided with the supporting part (7) integrally and has an illumination optical system (13) projecting an illumination beam toward photographing objective eyes (E) along an illumination optical axis (O2) intersected at a predetermined angle with a photographing optical axis (O1).

摘要翻译： 根据本发明的便携式荧光装置（1）包括支撑部分（7），具有拍摄照相机（5）的便携式电话（2）可拆卸地安装在该支撑部分（7）上，主体（6）设置有支撑 部分（7）整体地具有照明光学系统（13），其沿着与拍摄光轴（O 1）以预定角度相交的照明光轴（O 2）将照明光束投射到拍摄目标眼睛（E）。

公开(公告)号：US06802609B2

公开(公告)日：2004-10-12

申请号：US09851729

申请日：2001-05-09

申请人： Toshifumi Mihashi ,  Yoko Hirohara

发明人： Toshifumi Mihashi ,  Yoko Hirohara

IPC分类号： A61B310

CPC分类号： A61B3/107 ,  A61B3/103

摘要： The invention includes an eye characteristic measuring apparatus which achieves accurate measurement by taking a difference component with relation with measured data in a reference optical path when optical characteristics of an eye are measured. Specifically the measuring apparatus is provided with a reference optical system separate from a light receiving system. Measurement of eye characteristics can include both aberration of an eye and aberration in the measuring apparatus. In order to achieve high accuracy, the eye characteristic measuring apparatus of the invention substantially removes aberration in strain of the equipment produced after the initial stage and aberration of the equipment caused by deformation due to temperature.

摘要翻译： 本发明包括一种眼睛特征测量装置，当测量眼睛的光学特性时，通过在参考光学路径中与测量数据相关的差分分量来获得精确的测量。 具体地说，测量装置设有与光接收系统分开的参考光学系统。 眼睛特征的测量可以包括眼睛的像差和测量装置中的像差。 为了实现高精度，本发明的眼睛特征测量装置基本上消除了在初始阶段之后产生的设备的应变和由于温度引起的变形引起的设备的像差。