公开(公告)号：US07449452B2

公开(公告)日：2008-11-11

申请号：US11580936

申请日：2006-10-16

申请人： Tetsuya Suga ,  Yasuyo Suga ,  Masahiro Murata

发明人： Tetsuya Suga ,  Yasuyo Suga ,  Masahiro Murata

IPC分类号： A61N31/715

CPC分类号： G01N33/56972 ,  G01N2400/10 ,  Y10S435/975

摘要： The ability of a polysaccharide to act as an immunostimulant may be assessed by comparing the degree of binding of a detection reagent, which contains a fluorescence-labeled version of the polysaccharide, with the binding of a reference reagent, which contains a fluorescence-labeled version of a different polysaccharide. The ability of a polysaccharide to act as an immunostimulant may also be assessed by comparing the degree of binding of a detection reagent, which contains a fluorescence-labeled version of the polysaccharide, with the binding of a different type of reference reagent, which contains both the same fluorescence-labeled version of the polysaccharide and an unlabelled version of the same polysaccharide.

摘要翻译： 多糖用作免疫刺激剂的能力可以通过比较含有多糖的荧光标记形式的检测试剂与参考试剂的结合程度来评估，所述参考试剂含有荧光标记的版本 的不同多糖。 多糖用作免疫刺激剂的能力也可以通过比较含有多糖的荧光标记形式的检测试剂与不同类型参考试剂的结合的程度来评估，所述参考试剂含有两者 多糖的相同的荧光标记版本和相同多糖的未标记的版本。

公开(公告)号：US20070031898A1

公开(公告)日：2007-02-08

申请号：US11580936

申请日：2006-10-16

申请人： Tetsuya Suga ,  Yasuyo Suga ,  Masahiro Murata

发明人： Tetsuya Suga ,  Yasuyo Suga ,  Masahiro Murata

IPC分类号： G01N33/567 ,  A61K31/716

CPC分类号： G01N33/56972 ,  G01N2400/10 ,  Y10S435/975

摘要： A kit for the determination of the ability of a peripheral blood mononuclear cell to bind to a polysaccharide herein provided comprises a detection reagent comprising a fluorescence-labeled immunostimulant polysaccharide; and a reference reagent comprising a fluorescence-labeled material of a polysaccharide different from that used in the fluorescence-labeled immunostimulant polysaccharide, and/or an immunostimulant polysaccharide which is not labeled with any fluorescent material and whose polysaccharide moiety is identical to that included in the fluorescence-labeled immunostimulant polysaccharide. The use of this kit would permit the estimation of the polysaccharide-binding ability of a peripheral blood mononuclear cell in a higher precision of estimation.

摘要翻译： 用于测定外周血单核细胞与本文提供的多糖结合的能力的试剂盒包括含有荧光标记的免疫刺激多糖的检测试剂; 和包含不同于荧光标记的免疫刺激多糖中使用的多糖的荧光标记物质的参考试剂，和/或未用任何荧光材料标记的多糖部分与其中包含的多糖部分相同的免疫刺激多糖 荧光标记免疫刺激多糖。 该试剂盒的使用将允许以更高的估计精度估计外周血单核细胞的多糖结合能力。