公开(公告)号：US08167654B2

公开(公告)日：2012-05-01

申请号：US12098363

申请日：2008-04-04

Applicant: Joseph Elku ,  Jim Fraser ,  Richard Gratton

Inventor： Joseph Elku ,  Jim Fraser ,  Richard Gratton

IPC: H01K1/00

CPC classification number: A61L2/08 ,  A61L2/10 ,  C02F1/325 ,  C02F2201/004 ,  H01J5/50 ,  H01J5/56 ,  H01R33/0809 ,  H01R33/965 ,  H01R33/97

Abstract: There is disclosed a lamp device including a longitudinal axis, a first elongate electrical connector and a second elongate electrical connector, each of the first elongate electrical connector and the second elongate connector being non-parallel with respect to the longitudinal axis. The present lamp device provides a reliable electric connection on the one hand, yet is relatively inexpensive, uncomplicated and simple to implement on the other hand.

Abstract translation: 公开了一种灯装置，其包括纵向轴线，第一细长电连接器和第二细长电连接器，每个第一细长电连接器和第二细长连接器相对于纵向轴线不平行。 本灯装置一方面提供可靠的电连接，另一方面相对便宜，不复杂，易于实现。

公开(公告)号：US08148699B2

公开(公告)日：2012-04-03

申请号：US12185425

申请日：2008-08-04

Applicant: Wes From ,  Boyko M. Tchavdarov ,  Mike Marcu ,  Richard Gratton ,  David Olson ,  Jim Fraser ,  Dusko A. Kezele

Inventor： Wes From ,  Boyko M. Tchavdarov ,  Mike Marcu ,  Richard Gratton ,  David Olson ,  Jim Fraser ,  Dusko A. Kezele

IPC: B01J19/08

CPC classification number: C02F1/325 ,  A61L2/10 ,  C02F1/006 ,  C02F1/32 ,  C02F2201/3225 ,  C02F2201/3227 ,  C02F2201/3228 ,  C02F2201/324 ,  C02F2201/328

Abstract: The present invention relates to a fluid treatment system comprising: an inlet; an outlet; and a fluid treatment zone disposed between the inlet and the outlet. The fluid treatment zone has disposed therein: (i) an elongate first radiation source assembly having a first longitudinal axis, and (ii) an elongate second radiation source assembly having a second longitudinal axis. The first longitudinal axis and the second longitudinal axis are non-parallel to each other and to a direction of fluid flow through the fluid treatment zone. The present fluid treatment system has a number of advantages including: it can treat large volumes of fluid (e.g., wastewater, drinking water or the like); it requires a relatively small “footprint”; it results in a relatively lower coefficient of drag resulting in an improved hydraulic pressure loss/gradient over the length of the fluid treatment system; and it results in relatively lower (or no) forced oscillation of the radiation sources thereby obviating or mitigating of breakage of the radiation source and/or protective sleeve (if present). Other advantages are discussed in the specification.

Abstract translation: 本发明涉及一种流体处理系统，包括：入口; 一个出口 以及设置在入口和出口之间的流体处理区。 流体处理区已设置在其中：（i）具有第一纵向轴线的细长的第一辐射源组件，和（ii）具有第二纵向轴线的细长的第二辐射源组件。 第一纵向轴线和第二纵向轴线彼此不平行，并且流体流过流体处理区域的方向。 本流体处理系统具有许多优点，包括：它可以处理大量流体（例如，废水，饮用水等）; 它需要相对较小的“足迹”; 它导致相对较低的阻力系数导致在流体处理系统的长度上改善的液压损失/梯度; 并且其导致辐射源的相对较低（或不）强制振荡，从而消除或减轻辐射源和/或保护套筒（如果存在）的断裂。 其他优点在说明书中讨论。

公开(公告)号：US20110180723A1

公开(公告)日：2011-07-28

申请号：US13054701

申请日：2009-07-15

Applicant: Michael Sasges ,  Jim Fraser

Inventor： Michael Sasges ,  Jim Fraser

IPC: B01J19/12

CPC classification number: A23L3/26 ,  A23C3/07 ,  A23C3/076 ,  A23L2/50 ,  A23L3/28 ,  A61L2/08 ,  A61L2/10 ,  A61L2202/122 ,  C02F1/325 ,  C02F2201/3227 ,  C02F2201/328

Abstract: There is described a fluid treatment system in which fluid to be treated is impinged under pressure on a radiation emitting surface. The fluid treatment system includes at least one radiation source having a radiation emitting surface and at least one nozzle element having a fluid discharge opening spaced from the radiation emitting surface. The fluid discharge opening is configured to impinge fluid to be treated on to at least a portion of the radiation emitting surface. The fluid treatment system is well suited to treating low transmittance fluid.

Abstract translation: 描述了一种流体处理系统，其中待处理的流体在压力下撞击在辐射发射表面上。 流体处理系统包括具有辐射发射表面的至少一个辐射源和具有与辐射发射表面间隔开的流体排放口的至少一个喷嘴元件。 流体排放口构造成将待处理的流体冲击到辐射发射表面的至少一部分。 流体处理系统非常适合于处理低透光率液体。

公开(公告)号：US20100193421A1

公开(公告)日：2010-08-05

申请号：US12514894

申请日：2007-11-06

Applicant: Li Zheng Ma ,  George Traubenberg ,  Douglas Penhale

Inventor： Li Zheng Ma ,  George Traubenberg ,  Douglas Penhale

IPC: C02F1/32

CPC classification number: C02F1/325 ,  C02F2201/3225 ,  C02F2201/3227 ,  C02F2201/328

Abstract: In one of its aspects, the present invention relates to a fluid treatment system comprising: an inlet; an outlet; a fluid treatment zone disposed between the inlet and the outlet. The fluid treatment zone: (i) comprises a first wall surface and a second wall surface opposed to the first wall surface, and (ii) having disposed therein at least one array of rows of radiation source assemblies. Each radiation source assembly has a longitudinal axis transverse to a direction of fluid flow through the fluid treatment zone and each of the first wall surface and the second wall surface comprises a first fluid deflector element and a second fluid deflector element. The first fluid deflector element projecting into the fluid treatment zone to a greater extent than the second fluid deflector element.

Abstract translation: 在其一个方面，本发明涉及一种流体处理系统，包括：入口; 一个出口 设置在入口和出口之间的流体处理区。 流体处理区：（i）包括与第一壁表面相对的第一壁表面和第二壁表面，以及（ii）在其中设置有至少一排辐射源组件的阵列。 每个辐射源组件具有横向于流过流体处理区的流体流动方向的纵向轴线，并且第一壁表面和第二壁表面中的每一个包括第一流体偏转器元件和第二流体偏转器元件。 所述第一流体导流元件比所述第二流体导流元件突出到所述流体处理区域更大的程度。

公开(公告)号：US20100190691A1

公开(公告)日：2010-07-29

申请号：US12694122

申请日：2010-01-26

Applicant: Agamemnon A. Epenetos ,  Christina Kousparou

Inventor： Agamemnon A. Epenetos ,  Christina Kousparou

IPC: A61K38/16 ,  C07K9/00 ,  C12N5/02

CPC classification number: C12N15/113 ,  A61K47/64 ,  C12N15/111 ,  C12N2310/14 ,  C12N2310/3513 ,  C12N2320/32

Abstract: The present invention is based on the innovative concept of conjugating a cell-penetrating peptide (CPP), including a protein transduction domain, to a nucleic acid molecule to provide a nucleic acid-protein conjugate exhibiting enhanced cellular uptake. Accordingly, the invention provides a method of producing a cell permeable nucleic acid molecule conjugate nucleic acid including a nucleic acid conjugated with a homeodomain of an antennapedia homeotic transcription factor protein (Antp), or functional fragment thereof. The invention further provides compositions and methods treating a subject using the conjugates produced by the method described herein.

Abstract translation: 本发明基于将细胞穿透肽（CPP）（包括蛋白转导结构域）缀合到核酸分子以提供表现出增强的细胞摄取的核酸 - 蛋白质缀合物的创新概念。 因此，本发明提供一种生产细胞可渗透核酸分子缀合核酸的方法，所述核酸分子缀合核酸包含与触角异位转录因子蛋白（Antp）的同源结构域缀合的核酸或其功能片段。 本发明还提供了使用通过本文所述的方法产生的缀合物治疗受试者的组合物和方法。

公开(公告)号：US20100148094A1

公开(公告)日：2010-06-17

申请号：US12639142

申请日：2009-12-16

Applicant: DOUGLAS PENHALE ,  Joseph Elku ,  Bradley Hallett

Inventor： DOUGLAS PENHALE ,  Joseph Elku ,  Bradley Hallett

IPC: G21K5/02

CPC classification number: C02F1/325 ,  A61L9/20 ,  A61L2209/12 ,  C02F2201/006 ,  C02F2201/007 ,  C02F2201/3225 ,  C02F2201/3227

Abstract: There is disclosed an elongate radiation source cartridge. The cartridge comprises: (i) an elongate radiation source assembly having a proximal portion and distal portion, the distal portion of the elongate radiation source assembly being unsupported, (ii) a housing coupled to the proximal portion of the elongate radiation source assembly, and (iii) a power supply disposed within the housing, the power supply in electrical communication with the elongate radiation source assembly (in certain embodiments the power supply is optional). The elongate radiation source assembly and the housing are in substantial alignment with respect to a longitudinal axis of the elongate radiation source cartridge.

Abstract translation: 公开了一种细长的辐射源盒。 盒包括：（i）具有近端部分和远端部分的细长辐射源组件，细长辐射源组件的远端部分未被支撑，（ii）耦合到细长辐射源组件的近侧部分的壳体，以及 （iii）设置在壳体内的电源，与细长辐射源组件电连通的电源（在某些实施例中，电源是可选的）。 细长辐射源组件和壳体相对于细长辐射源盒的纵向轴线基本对准。

公开(公告)号：US20090294689A1

公开(公告)日：2009-12-03

申请号：US12158835

申请日：2006-12-21

Applicant: Jim Fraser ,  Michael Sasges

Inventor： Jim Fraser ,  Michael Sasges

IPC: G01N23/12 ,  G21G5/00

CPC classification number: A61L2/10 ,  C02F1/325 ,  C02F2201/004 ,  C02F2303/14

Abstract: There is described a fluid treatment system which may which may be used with radiation sources that do not require a protective sleeve—e.g., excimer radiation sources. An advantage of the present fluid system treatment is that the radiation sources may be removed from the fluid treatment zone without necessarily having to shut down the fluid treatment system, remove the fluid, break the seals which retain fluid tightness, replace/service radiation source and than reverse the steps. Instead, the present fluid treatment system allows for service/replacement of the radiation sources in the fluid treatment zone during operation of the fluid treatment system.

Abstract translation: 描述了可以与不需要保护套筒（例如准分子辐射源）的辐射源一起使用的流体处理系统。 本发明的流体系统处理的优点是可以从流体处理区域去除辐射源，而不必关闭流体处理系统，去除流体，破坏保持流体密封性的密封件，更换/使用辐射源和 反转步骤。 相反，本流体处理系统允许在流体处理系统的操作期间对流体处理区域中的辐射源进行维修/更换。

公开(公告)号：US20080260602A1

公开(公告)日：2008-10-23

申请号：US12144314

申请日：2008-06-23

Applicant: George A. TRAUBENBERG ,  Jason J. Cerny ,  Mike Marcu ,  Michael P. Sarchese ,  David E. Sproule

Inventor： George A. TRAUBENBERG ,  Jason J. Cerny ,  Mike Marcu ,  Michael P. Sarchese ,  David E. Sproule

IPC: B01J19/12 ,  C02F1/32 ,  A61L2/08

CPC classification number: C02F1/325 ,  C02F2201/3227 ,  C02F2303/14

Abstract: A radiation source module comprising a support member, a radiation source assembly connected to the support member and a seal disposed on a first surface of the module, the seal operable to provide a substantially fluid tight seal between the first surface and a second surface which is adjacent to the first surface.

Abstract translation: 辐射源模块，包括支撑构件，连接到支撑构件的辐射源组件和设置在模块的第一表面上的密封件，所述密封件可操作以在第一表面和第二表面之间提供基本上流体密封的密封， 邻近第一表面。

公开(公告)号：US07045102B2

公开(公告)日：2006-05-16

申请号：US10678637

申请日：2003-10-06

Applicant: Jim Fraser ,  Wesley From ,  Steven Bakker

Inventor： Jim Fraser ,  Wesley From ,  Steven Bakker

IPC: B01J19/08 ,  C02F1/32

CPC classification number: A61L2/10 ,  C02F1/325 ,  C02F2201/3227 ,  C02F2201/324

Abstract: A fluid treatment system for placement in a flanged pipe fluid conveyance system includes: a first flanged opening and a second flanged opening in substantial alignment to define a flow axis aligned substantially parallel to a direction of fluid flow though the first opening and the second opening; and a third flanged opening comprising a first cover element. The first cover element has connected thereto at least one radiation source assembly comprising at least one elongate radiation source having a longitudinal axis substantially transverse to the flow axis. The fluid treatment system may be advantageously utilized to treat fluid such as water, e.g., municipal waste water, municipal drinking water and the like. The fluid treatment system can be readily “spliced” into existing into existing piping systems. This facilitates installation of the system and also allows for a significant lowering of manufacturing costs of the system.

Abstract translation: 用于放置在法兰管道流体输送系统中的流体处理系统包括：第一凸缘开口和第二凸缘开口，其基本上对准以限定基本上平行于通过第一开口和第二开口的流体流动方向排列的流动轴线; 以及包括第一盖元件的第三凸缘开口。 第一覆盖元件已连接至少一个辐射源组件，该辐射源组件包括至少一个具有基本上横向于流动轴线的纵向轴线的细长辐射源。 流体处理系统可以有利地用于处理诸如水的流体，例如城市废水，市政饮用水等。 流体处理系统可以容易地“拼接”成现有的管道系统。 这有助于系统的安装，并且还可以显着降低系统的制造成本。

公开(公告)号：US07031849B2

公开(公告)日：2006-04-18

申请号：US10384782

申请日：2003-03-11

Applicant: Yuri Lawryshyn ,  David A. Olson ,  Harold Wright

Inventor： Yuri Lawryshyn ,  David A. Olson ,  Harold Wright

IPC: G06F19/00

CPC classification number: C02F1/325 ,  C02F1/008 ,  C02F1/32 ,  C02F2201/326 ,  G01F1/00

Abstract: An online device and method for predicting at least one fluid flow parameter in a process (which comprises a bounded flow domain having disposed therein a pre-determined matrix) includes a computer and/or process steps whereby: (i) a memory receives a database, the database comprising location information for a plurality of nodes or particle pathways in the matrix; (ii) input data is received from the process, and (iii) the at least one fluid flow parameter is calculated from the database and the input data. Preferably, structure and/or process steps are provided to adjust the database in the event that the input data does not correspond with at least one pre-determined flow state.

Abstract translation: 一种用于在过程（其包括其中设置有预定矩阵的有界流域）中预测至少一个流体流参数的在线设备和方法包括计算机和/或处理步骤，其中：（i）存储器接收数据库 所述数据库包括所述矩阵中多个节点或粒子通路的位置信息; （ii）从该过程接收输入数据，以及（iii）从数据库和输入数据计算至少一个流体流量参数。 优选地，提供结构和/或处理步骤以在输入数据与至少一个预定流量状态不对应的情况下调整数据库。