公开(公告)号：US20230065107A1

公开(公告)日：2023-03-02

申请号：US17446730

申请日：2021-09-02

申请人： International Business Machines Corporation

发明人： Emanuel Marc Löertscher ,  Diego Monserrat Lopez

IPC分类号： A61M60/441 ,  A61M5/142 ,  A61M60/122 ,  A61M60/508 ,  A61M60/268

摘要： An invention directed to an implant device having a biointerface. The implant device comprises a cavity and a structure enabling a flow path between the cavity and an environment of the implant device. An actuatable membrane is interposed in the flow path. The device includes a power-generating unit and a control unit, where the latter is connected to the power-generating unit. An electromechanical is connected to both the control unit and the power-generating unit. The electromechanical system includes at least one actuator configured to mechanically contact the membrane. This actuator is permanently attached to the membrane. The control unit and the electromechanical system are jointly configured to cause the electromechanical system to controllably actuate the membrane via at least one actuator to control a transfer of substances between the cavity and the environment through the flow path. The invention is further directed to related operation and fabrication methods.

公开(公告)号：US20230025881A1

公开(公告)日：2023-01-26

申请号：US17784723

申请日：2020-10-10

申请人： GAMBRO LUNDIA AB

发明人： Christian VARTIA

IPC分类号： A61M1/34 ,  A61M1/36 ,  A61M60/279 ,  A61M60/113 ,  A61M60/441 ,  A61M60/37

摘要： A blood ultrafiltration system comprises a blood filter with first and second compartments separated by a semipermeable membrane. Blood input and blood output lines are connected in fluid communication with the first compartment. An effluent line is connected in fluid communication with the second compartment. A peristaltic pump is arranged for repeated engagement with first and second line segments. In a first arrangement, the first line segment is part of the blood input line or the blood output line and the second line segment is part of the effluent line. In a second arrangement, the first line segment is part of the blood input line and the second line segment is part of the blood output line. The system is operable, by the peristaltic pump, to pump blood through the blood filter and control the extraction of ultrafiltrate in the blood filter.