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    System, method and computer-accessible medium for treating circulating tumor cells in the blood stream
    4.
    发明授权
    System, method and computer-accessible medium for treating circulating tumor cells in the blood stream 有权

    公开(公告)号：US11596788B2

    公开(公告)日：2023-03-07

    申请号：US16082199

    申请日：2017-03-02

    申请人： MEMORIAL SLOAN-KETTERING CANCER CENTER

    发明人： Govindarajan Srimathveeravalli ,  Stephen Barnett Solomon

    IPC分类号： A61N1/36 ,  A61M1/36 ,  A61N1/04 ,  A61N1/32 ,  A61N1/40 ,  A61M60/279 ,  A61M60/441 ,  A61M60/36 ,  A61M60/113

    摘要： An exemplary apparatus, can include, for example, a circulating tumor cell (CTC) treatment arrangement, a pump arrangement configured to circulate a fluid through the CTC treatment arrangement, and an electric field generator electrically connected to the CTC treatment arrangement, and configured to apply an electric field to the fluid circulating through the CTC treatment arrangement. The pump arrangement can be a peristaltic pump, which can be configured to continuously circulate the fluid through the CTC treatment arrangement. According to another exemplary embodiment of the present disclosure, method, system and computer-accessible medium can be provided for killing at least one circulating tumor cell (CTC). Using such exemplary embodiment, blood can be pumped from a body of a patient to an electroporation chamber inside of a CTC treatment arrangement. An electric field can be applied to the blood located in the electroporation chamber in order to kill the CTC. The electric field-applied blood can be pumped back into the body.

    Cooling of a Drive System for Diaphragm Pumps
    5.
    发明申请
    Cooling of a Drive System for Diaphragm Pumps 有权

    公开(公告)号：US20220126084A1

    公开(公告)日：2022-04-28

    申请号：US17423099

    申请日：2020-01-15

    申请人： Berlin Heart GmbH

    发明人： Matthew OAKLEY ,  Norbert SCHWIERTZ

    IPC分类号： A61M60/441 ,  A61M60/117 ,  A61M60/268 ,  A61M60/435 ,  A61M60/835 ,  F04B43/04

    摘要： A drive unit for a diaphragm pump may be provided, wherein the drive unit comprises a hollow body and a piston which is arranged so as to be movable in the first hollow body along an axis of the hollow body, wherein the piston divides the hollow body into a first chamber, which is connectable to the diaphragm pump, and a second chamber, which is coupleable to a gas reservoir. The second chamber comprises an inlet valve and an outlet valve, such that a gas flow is drawn into the chamber via the inlet valve and is forced out of the chamber via the outlet valve.

    PUMP SYSTEM FOR PUMPING A FLUID AND METHOD FOR OPERATING A PUMP SYSTEM
    6.
    发明申请
    PUMP SYSTEM FOR PUMPING A FLUID AND METHOD FOR OPERATING A PUMP SYSTEM 有权

    公开(公告)号：US20220111196A1

    公开(公告)日：2022-04-14

    申请号：US17268900

    申请日：2019-08-16

    申请人： Berlin Heart GmbH

    发明人： Robert Steingräber

    IPC分类号： A61M60/554 ,  A61M60/523 ,  A61M60/268 ,  A61M60/441 ,  A61M60/427 ,  A61M60/894 ,  A61M60/178

    摘要： A pump system is provided for pumping a fluid and a method is provided for operating the pump system. The pump system comprises a first diaphragm fluid pump, a first inlet cannula connected to the first diaphragm fluid pump for supplying a fluid to the first diaphragm fluid pump, a first outlet cannula connected to the first diaphragm fluid pump for discharging the fluid out of the first diaphragm fluid pump, and a first service pump, which is connected via a first pressure line to the first diaphragm fluid pump and is confirmed to drive the first diaphragm fluid pump via the first pressure line. The pump system further comprises a first inlet flow sensor for detecting a first inlet flow of the fluid in the first inlet cannula and/or a first outlet flow sensor for detecting a first outlet flow of the fluid in the first outlet cannula.