公开(公告)号：US20050065144A1

公开(公告)日：2005-03-24

申请号：US10934308

申请日：2004-09-02

申请人： Jun Feng ,  Stephen Gwaltney ,  Jeffrey Stafford ,  Zhiyuan Zhang

发明人： Jun Feng ,  Stephen Gwaltney ,  Jeffrey Stafford ,  Zhiyuan Zhang

IPC分类号： A61K31/44 ,  A61K31/54 ,  C07D211/84 ,  C07D401/04

CPC分类号： C07D401/14 ,  C07D401/04

摘要： Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV inhibitors comprising Formula Ia or Ib: wherein the substituents are as described herein.

摘要翻译： 提供化合物，药物，试剂盒和方法用于包含式Ia或Ib的DPP-IV抑制剂：其中取代基如本文所述。

公开(公告)号：US06837927B2

公开(公告)日：2005-01-04

申请号：US10060922

申请日：2002-01-29

申请人： Peter R. David

发明人： Peter R. David

IPC分类号： C30B7/00 ,  G01N25/14 ,  C30B9/02

CPC分类号： C30B7/00 ,  B01J2219/00274 ,  B33Y80/00 ,  C30B29/58 ,  G01N25/147

摘要： A microfluidic device is provided that comprises: a substrate; and a plurality of microvolumes at least partially defined by the substrate, each microvolume comprising a first submicrovolume and a second submicrovolume that is in fluid communication with the first submicrovolume when the device is rotated, the plurality of microvolumes being arranged in the device such that fluid in the first submicrovolumes of multiple of the microvolumes are transported to second submicrovolumes of the associated microvolumes when the device is rotated.

公开(公告)号：US06837926B2

公开(公告)日：2005-01-04

申请号：US10060861

申请日：2002-01-29

申请人： Peter R. David

发明人： Peter R. David

IPC分类号： C30B7/00 ,  G01N25/14 ,  C30B29/54

CPC分类号： C30B7/00 ,  B01J2219/00274 ,  B33Y80/00 ,  C30B29/58 ,  G01N25/147 ,  Y10T117/10

摘要： A microfluidic device is provided that comprises: a card shaped substrate having first and second opposing faces; one or more microvolumes at least partially defined by a first face of the card shaped substrate; and one or more grooves at least partially defined by a second face of the card shaped substrate; wherein a lateral footprint of at least a portion of the one or more grooves overlaps with a lateral footprint of at least one of the one or more microvolumes.

摘要翻译： 提供一种微流体装置，其包括：具有第一和第二相对面的卡形基板; 至少部分地由卡片形基底的第一面限定的一个或多个微卷; 以及至少部分地由所述卡形基板的第二面限定的一个或多个凹槽; 其中所述一个或多个凹槽的至少一部分的横向足迹与所述一个或多个微卷轴中的至少一个微卷轴的横向覆盖区重叠。

公开(公告)号：US20040242566A1

公开(公告)日：2004-12-02

申请号：US10809638

申请日：2004-03-24

申请人： Syrrx, Inc.

发明人： Jun Feng ,  Stephen L. Gwaltney ,  Stephen W. Kaldor ,  Jeffrey A. Stafford ,  Michael B. Wallace ,  Zhiyuan Zhang

IPC分类号： A61K031/549 ,  A61K031/517 ,  A61K031/519

CPC分类号： C07D471/04 ,  C07D401/04 ,  C07D403/04 ,  C07D473/18 ,  C07D487/04

摘要： Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV and othe S9 proteases that comprise a compound comprising the formula: 1 wherein Q is selected from the group consisting of CO, SO, SO2, or CnullNR9; and R1, R2, R3 and R4 as defined herein.

摘要翻译： 提供化合物，药物，试剂盒和方法用于DPP-IV和S9蛋白酶，其包含下式的化合物：其中Q选自CO，SO，SO 2或C = NR 9; 和如本文所定义的R 1，R 2，R 3和R 4。