公开(公告)号：US06870368B2

公开(公告)日：2005-03-22

申请号：US10067429

申请日：2002-02-05

Applicant: Frederik Visser ,  Paulus Cornelius Hendrikus Adrianus Haans ,  Johan Samuel Van Den Brink

Inventor： Frederik Visser ,  Paulus Cornelius Hendrikus Adrianus Haans ,  Johan Samuel Van Den Brink

IPC: A61B5/055 ,  G01R33/3415 ,  G01R33/54 ,  G01V3/00

CPC classification number: G01R33/3415 ,  G01R33/4835

Abstract: The proposed MRI apparatus provides a solution to the problem of a limited number of receiver channels. The main idea is to make use of the imaging parameters when selecting and/or combining the RF signals of at least two RF coils into separate receiver channels. Such an imaging parameter may be, for example, the phase encoding direction.

Abstract translation: 所提出的MRI装置提供了有限数量的接收机通道的问题的解决方案。 主要思想是在将至少两个RF线圈的RF信号选择和/或组合成分离的接收器通道时，利用成像参数。 这样的成像参数可以是例如相位编码方向。

公开(公告)号：US06556010B2

公开(公告)日：2003-04-29

申请号：US09880209

申请日：2001-06-13

Applicant: Johan Samuel Van Den Brink ,  Julius Simon Cohen

Inventor： Johan Samuel Van Den Brink ,  Julius Simon Cohen

IPC: G01V300

CPC classification number: G01R33/5611 ,  G01R33/246 ,  G01R33/3415 ,  G01R33/56545 ,  G01R33/5659

Abstract: A magnetic resonance imaging system is provided with a system of emission antennas,: for example, emission coils, for generating RF excitation pulses. The RF excitation pulses generate magnetic resonance signals from an object to be examined. The system of emission antennas has a spatially inhomogeneous emission profile. The inhomogeneous emission profile is used for the partial spatial encoding of the magnetic resonance signals in addition to the encoding on the basis of magnetic gradient fields. The magnetic resonance image is reconstructed on the basis of the inhomogeneous emission profile

Abstract translation: 磁共振成像系统设置有用于产生RF激励脉冲的发射天线系统，例如发射线圈。 RF激励脉冲从被检查物体产生磁共振信号。 发射天线系统具有空间不均匀的发射特征。 除了基于磁梯度场的编码之外，不均匀发射分布用于磁共振信号的部分空间编码。 基于非均匀发射谱重建磁共振图像

公开(公告)号：US09297870B2

公开(公告)日：2016-03-29

申请号：US13700137

申请日：2011-05-19

Applicant: Johan Samuel Van Den Brink

Inventor： Johan Samuel Van Den Brink

IPC: G01V3/00 ,  G01R33/385 ,  G01R33/28 ,  G01R33/561 ,  G01R33/54

CPC classification number: G01R33/3852 ,  G01R33/285 ,  G01R33/288 ,  G01R33/54 ,  G01R33/5613

Abstract: An magnetic resonance examination system for examination of an object comprises an RF system to generate an RF transmission field and gradient system to generate temporary magnet gradient fields. A control module includes a sequence controller to control the RF system and the gradient system to produce acquisition sequences including RF pulses and magnetic gradient pulses to generate magnetic resonance signals. The sequence controller is configured to produce an detection scan including a steady state gradient echo acquisition sequence to generate steady state gradient echo signals and an RF spoiled echo acquisition sequence to produce RF spoiled echo signals. The control module further including an analysis unit to compare the gradient echo signals to the RF spoiled echo signals and for detection of an instrument in the object from the comparison of the gradient echoes and the RF spoiled echoes.

Abstract translation: 用于检查物体的磁共振检查系统包括用于产生RF传输场的RF系统和用于产生临时磁体梯度场的梯度系统。 控制模块包括用于控制RF系统和梯度系统以产生包括RF脉冲和磁梯度脉冲的采集序列以产生磁共振信号的序列控制器。 序列控制器被配置为产生包括稳态梯度回波采集序列的检测扫描，以产生稳态梯度回波信号和RF损坏的回波采集序列以产生RF损坏回波信号。 控制模块还包括分析单元，用于将梯度回波信号与RF损坏的回波信号进行比较，并且用于通过梯度回波和RF损坏回波的比较来检测物体中的仪器。

公开(公告)号：US20130225974A1

公开(公告)日：2013-08-29

申请号：US13883917

申请日：2011-10-31

Applicant: Johan Samuel Van Den Brink

Inventor： Johan Samuel Van Den Brink

IPC: A61N5/10 ,  A61B5/055

CPC classification number: A61N5/1039 ,  A61B5/055 ,  A61N5/1048 ,  A61N5/1049 ,  A61N5/1081 ,  A61N2005/1055 ,  G01R33/4808

Abstract: A therapeutic apparatus (100) comprising: a radio therapy apparatus (102) for treating a target zone (146) of a subject (144), wherein the radio therapy apparatus comprises a radio therapy source (110) for generating electromagnetic radiation (114), wherein the radio therapy apparatus is adapted for rotating the radio therapy source about a rotational point (116); a mechanical actuator (104) for supporting the radio therapy apparatus and for moving the position and/or orientation of the rotational point; and a magnetic resonance imaging system (106) for acquiring magnetic resonance data (170) from an imaging zone (138), wherein the target zone is within the imaging zone, wherein the magnetic resonance imaging system comprises a magnet (122) for generating a magnetic field within the imaging zone, wherein the radio therapy source is adapted for rotating at least partially about the magnet.

Abstract translation: 一种治疗装置，包括：用于治疗受检者（144）的目标区域（146）的放射治疗装置（102），其中所述无线电治疗装置包括用于产生电磁辐射的无线电治疗源（110） ，其中所述放射治疗装置适于围绕旋转点（116）旋转所述放射治疗源; 用于支撑所述无线电治疗装置并用于移动所述旋转点的位置和/或取向的机械致动器（104） 以及用于从成像区域（138）获取磁共振数据（170）的磁共振成像系统（106），其中所述目标区域在所述成像区域内，其中所述磁共振成像系统包括磁体（122），用于产生 所述成像区域内的磁场，其中所述无线电治疗源适于至少部分地绕所述磁体旋转。

公开(公告)号：US20100277174A1

公开(公告)日：2010-11-04

申请号：US12808399

申请日：2008-12-22

Applicant: Johan Samuel Van Den Brink ,  Cornelis Leonardus Gerardus Ham

Inventor： Johan Samuel Van Den Brink ,  Cornelis Leonardus Gerardus Ham

IPC: G01R33/48

CPC classification number: G01R33/3873 ,  G01R33/34007 ,  G01R33/341 ,  G01R33/3415 ,  G01R33/5659

Abstract: A magnetic resonance imaging system (10) includes a local coil (40) for receiving a resonance signal induced by a whole body quadrature coil (32). The local coil (40) includes a dielectric former (68) in which a plurality of receive coils (60, 74, 76, 78) and a passive B0 and B1 field shim (62, 82) are mounted. The passive shim includes a plurality of capacitively coupled elements (64) of an electrically conductive diamagnetic, paramagnetic, ferromagnetic material which passively shield and enhance the field in local regions. A surface configuration of the elements is tailored to optimize local B1 homogeneity and a mass of the elements is configured to optimize local B0 field homogeneity.

Abstract translation: 磁共振成像系统（10）包括用于接收由全身正交线圈（32）感应的谐振信号的局部线圈（40）。 局部线圈（40）包括电介质成形器（68），其中安装有多个接收线圈（60,74,76,78）和无源B0和B1场垫片（62,82）。 被动垫片包括多个电容耦合元件（64），其导电的抗磁性，顺磁性的铁磁材料被动地屏蔽和增强局部区域中的场。 元件的表面配置被定制以优化局部B1均匀性，并且元件的质量被配置为优化局部B0场均匀性。

公开(公告)号：US07746072B2

公开(公告)日：2010-06-29

申请号：US11909164

申请日：2006-03-20

Applicant: Marinus Johannes Adrianus Maria Van Helvoort ,  Marc Paul Saes ,  Johan Samuel Van Den Brink ,  Robert Paul Kleihorst ,  Paulus Cornelius Hendrikus Adrianus Haans

Inventor： Marinus Johannes Adrianus Maria Van Helvoort ,  Marc Paul Saes ,  Johan Samuel Van Den Brink ,  Robert Paul Kleihorst ,  Paulus Cornelius Hendrikus Adrianus Haans

IPC: G01V3/00

CPC classification number: G01R33/3621 ,  G01R33/3415 ,  G01R33/3692

Abstract: The present invention relates to a magnetic resonance imaging system, to a magnetic resonance imaging method for operating a magnetic resonance imaging system and to a computer program for operating a magnetic resonance imaging system. In order to considerably reduce the number of cabling in a magnetic resonance imaging system a magnetic resonance imaging system (1) is suggested, the system comprising: an examination zone (5) arranged to receive a body for examination; magnetic field generating means (9, 10, 24) for generating a magnetic field in the examination zone (5); a receiving unit (14) located in the examination zone (5) or in the vicinity of the examination zone (5); an interface unit (17) located in the examination zone (5) or in the vicinity of the examination zone (5), and arranged separately from the receiving unit (14); and a signal processing unit (21) disposed at a location (2) remote from the receiving unit (14) and the interface unit (17); wherein the receiving unit (14) comprising a receiver (15) adapted to receive a spin resonance signal generated in the examination zone (5), and a transmitter (16) adapted to transmit the spin resonance signal to the interface unit (17); and wherein the interface unit (17) comprises a receiver (20) for receiving the spin resonance signals, an analog to digital converter (19) adapted to generate a digital signal in response to the received spin resonance signal, and a transmitter (20) for transmitting the digitized signal to the signal processing unit (21).

Abstract translation: 磁共振成像系统技术领域本发明涉及一种用于操作磁共振成像系统的磁共振成像方法和用于操作磁共振成像系统的计算机程序的磁共振成像系统。 为了大大减少磁共振成像系统中的电缆数量，建议使用磁共振成像系统（1），该系统包括：检查区域（5），布置成接收检查体; 用于在检查区（5）中产生磁场的磁场产生装置（9,10,24）; 位于检查区（5）或检查区（5）附近的接收单元（14）; 位于所述检查区域（5）中或所述检查区域（5）附近的接口单元（17），并且与所述接收单元（14）分开布置; 以及设置在远离所述接收单元（14）和所述接口单元（17）的位置（2）处的信号处理单元（21）。 其中所述接收单元（14）包括适于接收在所述检查区（5）中产生的自旋共振信号的接收器（15）和适于将所述自旋共振信号传输到所述接口单元（17）的发射器（16）。 并且其中所述接口单元（17）包括用于接收所述自旋谐振信号的接收器（20），适于响应于所接收的自旋谐振信号产生数字信号的模数转换器（19），以及发射器（20） 用于将数字化信号发送到信号处理单元（21）。

公开(公告)号：US20080303519A1

公开(公告)日：2008-12-11

申请号：US11573019

申请日：2005-07-21

Applicant: Johan Samuel Van Den Brink ,  Tatiana Borisovna Sazonova

Inventor： Johan Samuel Van Den Brink ,  Tatiana Borisovna Sazonova

IPC: G01R33/34

CPC classification number: G01R33/3415

Abstract: The magnetic resonance apparatus comprises a carrier (8) to position an object (7), notably a patient to be imaged in an imaging volume V, first magnet system (2), a second magnet system (3), a power supply unit (4), an RF transmitter and modulator (6), an RF transmitter coil (5), a plurality of receiver elements (18, 19), a transmitter-receiver circuit (9), a signal amplifier and demodulation unit (10), a processing unit (12), an image processing unit (13), a monitor (14), and a control unit (11). The gradient coils (3) are fed by the power supply unit (4). The RF transmitter coil (5) serves to generate RF magnetic fields and is connected to the RF transmitter and modulator (6). The transmitter coil (5) is connected to the signal amplifier and demodulator unit (10) via the transmitter-receiver circuit (9). Receiver elements (18, 19), positioned at their respective locations L1, L2 on the carrier (8), are arranged to detect a response of the object to the RF magnetic fields. The control unit (11) controls the RF transmitter and modulator (6), the power supply unit (4) and automatically selects suitable receiver elements (18, 19) to detect the response of the object (7) to the magnetic resonance excitation.

Abstract translation: 磁共振装置包括用于将物体（7）定位的载体（8），特别是成像体积V中要被成像的患者，第一磁体系统（2），第二磁体系统（3），电源单元 4），RF发射器和调制器（6），RF发射器线圈（5），多个接收器元件（18,19），发射器 - 接收器电路（9），信号放大器和解调单元（10） 处理单元（12），图像处理单元（13），监视器（14）和控制单元（11）。 梯形线圈（3）由电源单元（4）馈送。 RF发射器线圈（5）用于产生RF磁场并连接到RF发射器和调制器（6）。 发射机线圈（5）经由发射机 - 接收机电路（9）连接到信号放大器和解调器单元（10）。 布置在位于载体（8）上的各自位置L1，L2处的接收器元件（18,19），用于检测物体对RF磁场的响应。 控制单元（11）控制RF发射器和调制器（6），电源单元（4）并自动选择合适的接收器元件（18,19）以检测对象（7）对磁共振激励的响应。

公开(公告)号：US07420369B2

公开(公告)日：2008-09-02

申请号：US11568331

申请日：2005-04-26

Applicant: Johan Samuel Van Den Brink ,  Paul Royston Harvey

Inventor： Johan Samuel Van Den Brink ,  Paul Royston Harvey

IPC: G01V3/00

CPC classification number: G01R33/5601

Abstract: In order to provide a magnetic resonance imaging system and method which allows an optimal timing of the imaging sequence at minimal procedure cost, a magnetic resonance imaging system and method is proposed, wherein a first MR scan of a structure of interest is performed for detecting the arrival of a contrast bolus in the structure of interest, the first MR scan using a first resonance frequency corresponding to first MR sensitive nuclei, the first performing step is repeated at least until the bolus arrival in the structure of interest has been detected, and a second MR scan of the structure of interest is performed for acquiring a MR image, the second MR scan using a second resonance frequency corresponding to second MR sensitive nuclei, the second nuclei being different from the first nuclei.

Abstract translation: 为了提供以最小程序成本实现成像序列的最佳定时的磁共振成像系统和方法，提出了一种磁共振成像系统和方法，其中执行感兴趣结构的第一MR扫描以检测 将造影剂团块到达感兴趣的结构中，使用对应于第一MR敏感核的第一共振频率的第一MR扫描，重复第一执行步骤，至少已经检测到到达感兴趣的结构中的推注， 执行感兴趣结构的第二MR扫描以获取MR图像，第二MR扫描使用对应于第二MR敏感核的第二共振频率，第二核与第一核不同。

公开(公告)号：US07057388B2

公开(公告)日：2006-06-06

申请号：US10535587

申请日：2003-10-27

Applicant: Paul Royston Harvey ,  Johan Samuel Van Den Brink

Inventor： Paul Royston Harvey ,  Johan Samuel Van Den Brink

IPC: G01V3/00

CPC classification number: G01R33/56341 ,  G01R33/56509

Abstract: The invention relates to a method for magnetic resonance imaging (MRI) of at least a portion of a body placed in a stationary and substantially homogeneous main magnetic field. The method comprises the steps of subjecting the body to a diffusion-weighting sequence (DW1), generating a train of MR echoes (E1, E2, E3, E4, E5) by an imaging sequence (EPI1), and measuring this train of MR echoes. These steps are repeated until a complete imaging data set with a sufficient number of phase-encoding steps is measured. Thereafter, the imaging data set is corrected for macroscopic motions by means of an individual phase-correction of each train of MR echoes. Finally, an image is reconstructed from the imaging data. In order to provide a method for diffusion-weighted imaging, which requires a minimum additional measurement time for determining the phase errors of the imaging signals and which also guarantees a robust compensation of image artifacts caused by macroscopic motions of the body of the examined patient, the invention suggests to select the phase-encoding scheme of the imaging sequence such that each train of MR echoes (E1, E2, E3, E4, E5) comprises at least one initial MR navigator echo (E1), which forms and integral part of the imaging data set, wherein the phase-correction is derived from the MR navigator echo.

Abstract translation: 本发明涉及一种放置在静止和基本上均匀的主磁场中的身体的至少一部分的磁共振成像（MRI）的方法。 该方法包括以下步骤：通过成像序列（EPI 1）对身体进行扩散加权序列（DW 1），产生MR回波序列（E 1，E 2，E 3，E 4，E 5） ，并测量这一列MR回波。 重复这些步骤，直到测量具有足够数量的相位编码步骤的完整成像数据集。 此后，通过对每个MR回波序列进行单独的相位校正，对宏观运动校正成像数据组。 最后，从成像数据重建图像。 为了提供扩散加权成像的方法，其需要用于确定成像信号的相位误差的最小额外测量时间，并且还保证对被检查患者的身体的宏观运动引起的图像伪像的鲁棒补偿， 本发明建议选择成像序列的相位编码方案，使得MR回波序列（E 1，E 2，E 3，E 4，E 5）包括至少一个初始MR导航回波（E 1）， 其形成和成像数据集的组成部分，其中从MR导航回波导出相位校正。

公开(公告)号：US06828790B2

公开(公告)日：2004-12-07

申请号：US10224049

申请日：2002-08-20

Applicant: Ulrich Katscher ,  Peter Boernert ,  Johan Samuel van den Brink

Inventor： Ulrich Katscher ,  Peter Boernert ,  Johan Samuel van den Brink

IPC: G01V300

CPC classification number: G01R33/446 ,  G01R33/3415 ,  G01R33/4616 ,  G01R33/5611

Abstract: A magnetic resonance imaging system comprises an excitation antennae system (13,16) including several antennae for emitting an RF-excitation field [B1(t)]. An activation control unit (ACU) is coupled to the excitation antennae system to activate the excitation antennae system. Individual antennae are activated to simultaneously emit separate RF-excitation constituents [Bn(t)]. The RF-excitation constituents have different activation distributions over k-space. and the time required for the RF-excitation is short even for complex spatial excitation patterns.

Abstract translation: 磁共振成像系统包括激励天线系统（13,16），其包括用于发射RF激励场[B1（t）]的几个天线。 激活控制单元（ACU）耦合到激励天线系统以激活激励天线系统。 单独的天线被激活以同时发射单独的RF激发成分[Bn（t）]。 RF激发成分在k空间上具有不同的激活分布。 即使对于复杂的空间激励模式，RF激发所需的时间也很短。