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公开(公告)号：US20140370543A1
公开(公告)日：2014-12-18
申请号：US13883187
申请日：2011-11-02
CPC分类号： C12P21/00 , C07K2319/02 , C07K2319/35 , C12N9/0051 , C12N9/90 , C12N15/70 , C12P21/02 , C12Y108/03002
摘要： A process for the production of a target recombinant polypeptide is provided. The process comprises expressing an expression cassette encoding the target polypeptide and co-expressing an expression cassette encoding a mitochondrial foldase. Preferred mitochondrial foldases include Mia 40 and Erv1, and homologs thereof.
摘要翻译： 提供了用于产生靶重组多肽的方法。 该方法包括表达编码靶多肽的表达盒，并共表达编码线粒体折叠酶的表达盒。 优选的线粒体折叠酶包括Mia 40和Erv1及其同系物。
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公开(公告)号：US20110270375A1
公开(公告)日：2011-11-03
申请号：US13181249
申请日：2011-07-12
IPC分类号： A61F2/84
CPC分类号： A61F2/954 , A61F2/07 , A61F2/82 , A61F2/90 , A61F2/958 , A61F2/962 , A61F2/966 , A61F2002/067 , A61F2002/9511 , A61F2002/9583 , A61F2002/9665
摘要： An introduction arrangement for a fenestrated or branched stent graft (13) intended for deployment into the lumen of a vessel having a blind vessel extending from it. The introducer (1) has a distal end intended to remain outside a patient in use and a proximal end with a nose cone dilator (11) and an arrangement to retain the branched stent graft distally of the nose cone dilator. A sheath (15) on the introducer extends over the branched stent graft to the nose cone dilator. An indwelling catheter (22) extends from the distal end of the introducer and enters the fenestration or side arm and through to the nose cone dilator, the indwelling catheter has a guide wire (29) extending through it. The guide wire can be extended beyond the nose cone dilator in use before the sheath is withdrawn from the branched stent graft so that it can be snared from the contra-lateral artery.
摘要翻译： 用于开窗或分枝的支架移植物（13）的引入装置，其用于展开到具有从其延伸的盲血管的血管的内腔中。 导引器（1）具有旨在在使用中保持在患者外部的远端和具有鼻锥形扩张器（11）的近端和用于将分支的支架移植物保持在鼻锥扩张器的远侧的布置。 引导器上的护套（15）在分支支架移植物上延伸到鼻锥扩张器。 留置导管（22）从引导器的远端延伸并进入开窗或侧臂并通过鼻锥扩张器，留置导管具有延伸通过其的导丝（29）。 引导线可以延伸到使用中的鼻锥扩张器之外，然后将护套从分支的支架移植物中取出，使得其可以从对侧动脉中截获。
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