公开(公告)号：US20100208971A1

公开(公告)日：2010-08-19

申请号：US12679961

申请日：2008-09-24

Applicant: Christoph Neukirchen ,  Matthias Bertram

Inventor： Christoph Neukirchen ,  Matthias Bertram

IPC: G06K9/00

CPC classification number: A61B6/504 ,  A61B6/032 ,  A61B6/4441 ,  A61B6/481 ,  A61B6/507

Abstract: It is provided a method for imaging a dynamic process in a part of the body, especially blood perfusion, with an x-ray system as well as corresponding apparatuses and a corresponding computer readable medium. Especially it is described a method for imaging a dynamic process in a part of the body, especially blood perfusion, with an x-ray system, comprising: acquiring rotational projections of the part of the body over an angular range (2), deriving the anatomy of the part of the body subject to the dynamic process using a tomographic reconstruction from the projections (3), determining an optimal position of the x-ray system according to the derived anatomy for acquiring projections of the dynamic process (4), administering contrast agent to the part of the body (5), acquiring projections of the dynamic process from the determined position (6); calculating the dynamic contrast enhancement over time (7); and calculating and displaying perfusion parameters (8).

Abstract translation: 提供了一种用于利用x射线系统以及对应的装置和相应的计算机可读介质对身体的一部分，特别是血液灌注中的动态过程进行成像的方法。 特别地，描述了一种利用x射线系统对身体的一部分，特别是血液灌注中的动态过程进行成像的方法，包括：在角度范围（2）上获取身体部分的旋转突起，导出 使用来自投影（3）的断层摄影重建的动态过程的身体部分的解剖结构，根据导出的解剖结构确定x射线系统的最佳位置以获取动态过程（4）的投影，管理 造影剂到身体的一部分（5），从确定的位置（6）获取动态过程的投影; 随着时间的推移计算动态对比度增强（7）; 并计算和显示灌注参数（8）。

公开(公告)号：US20090202127A1

公开(公告)日：2009-08-13

申请号：US12305983

申请日：2007-06-13

Applicant: Matthias Bertram ,  Jens Wiegert ,  Jan Timmer ,  Nicolaas Jan Noordhoek

Inventor： Matthias Bertram ,  Jens Wiegert ,  Jan Timmer ,  Nicolaas Jan Noordhoek

IPC: G06K9/00

CPC classification number: G06T11/005 ,  G06T5/003 ,  G06T2207/10081 ,  G06T2207/30004

Abstract: A method for generating a set of kernels for convolution error compensation of a projection image of a physical object recorded by an imaging system comprises calculating the set of kernels in such a way that for each pixel of the projection image an asymmetric scatter distribution for error compensation is calculated representing a X-ray scatter originating along a ray from an X-ray source to the pixel.

Abstract translation: 用于生成用于由成像系统记录的物理物体的投影图像的卷积误差补偿的一组内核的方法包括以对投影图像的每个像素进行误差补偿的不对称散布分布的方式来计算该组内核 表示沿着从X射线源到像素的射线发生的X射线散射。

公开(公告)号：US20090154787A1

公开(公告)日：2009-06-18

申请号：US11719554

申请日：2005-11-22

Applicant: Matthias Bertram ,  Til Aach ,  Georg Hans Rose ,  Dirk Schaefer

Inventor： Matthias Bertram ,  Til Aach ,  Georg Hans Rose ,  Dirk Schaefer

IPC: G06K9/00

CPC classification number: G06T11/005

Abstract: The present invention relates to an image reconstruction device and a corresponding method for reconstructing a 3D image of an object (7) from projection data of said object (7). In order to obtain 3D images having sharp high-contrast structures and almost no image blur, and in which streak artifacts (and noise in tissue-like regions) are strongly reduced, an image reconstruction device is proposed comprising: a first reconstruction unit (30) for reconstructing a first 3D image of said object (7) using the original projection data, an interpolation unit (31) for calculating interpolated projection data from said original projection data, —a second reconstruction unit (32) for reconstructing a second 3D image of said object (7) using at least the interpolated projection data, a segmentation unit (33) for segmentation of the first or second 3D image into high-contrast and low-contrast areas, a third reconstruction unit (34) for reconstructing a third 3D image from selected areas of said first and said second 3D image, wherein said segmented 3D image is used to select image values from said first 3D image for high-contrast areas and image values from said second 3D image for low-contrast areas.

Abstract translation: 本发明涉及一种从所述物体（7）的投影数据重建物体（7）的3D图像的图像重建装置和相应的方法。 为了获得具有锐利的高对比度结构并且几乎没有图像模糊的3D图像，并且其中强烈减少了条纹伪影（和组织样区域中的噪声），提出了一种图像重建装置，包括：第一重建单元（30 ），用于使用原始投影数据重建所述对象（7）的第一3D图像;内插单元（31），用于从所述原始投影数据计算内插投影数据;第二重建单元（32），用于重建第二3D图像 使用至少内插投影数据的分割单元（33），用于将第一或第二3D图像分割为高对比度和低对比度区域的分割单元（33），用于重建第三或第二3D图像的第三重建单元 所述第一和第二3D图像的所选区域的3D图像，其中所述分割的3D图像用于从所述第一3D图像中选择用于高对比度区域的图像值，并且来自所述第二3D图像的图像值 D图像用于低对比度区域。

公开(公告)号：US08483363B2

公开(公告)日：2013-07-09

申请号：US12740366

申请日：2008-11-04

Applicant: Matthias Bertram ,  Jens Wiegert ,  John F. Vesel ,  David Sowards-Emmerd ,  Michael J. Petrilo

Inventor： Matthias Bertram ,  Jens Wiegert ,  John F. Vesel ,  David Sowards-Emmerd ,  Michael J. Petrilo

IPC: G21K3/00

CPC classification number: A61B6/032 ,  A61B6/037 ,  A61B6/4035 ,  G21K1/10

Abstract: When generating a 3D image of a subject or patient, a cone beam X-ray source (20a, 20b) is mounted to a rotatable gantry (14) opposite an offset flat panel X-ray detector (22a, 22b). A wedge-shaped attenuation filter (24a, 24b) of suitable material (e.g., aluminum or the like) is adjustably positioned in the cone beam to selectively attenuate the beam as a function of the shape, size, and density of a volume of interest (18) through which X-rays pass in order to maintain X-ray intensity or gain at a relatively constant level within a range of acceptable levels.

Abstract translation: 当产生被摄体或患者的3D图像时，锥形束X射线源（20a，20b）安装到与偏移平板X射线检测器（22a，22b）相对的可旋转机架（14）。 适当材料（例如铝等）的楔形衰减滤波器（24a，24b）可调节地定位在锥形束中，以根据感兴趣体积的形状，尺寸和密度来选择性地衰减光束 （18），以便在可接受水平的范围内使X射线强度或增益保持在相对恒定的水平。

公开(公告)号：US20120321156A1

公开(公告)日：2012-12-20

申请号：US13582124

申请日：2011-03-04

Applicant: Irina Waechter-Stehle ,  Alexandra Groth ,  Ronaldus Petrus Johannes Hermans ,  Matthias Bertram

Inventor： Irina Waechter-Stehle ,  Alexandra Groth ,  Ronaldus Petrus Johannes Hermans ,  Matthias Bertram

IPC: G06K9/00

CPC classification number: G06T7/2053 ,  A61B6/4441 ,  A61B6/4464 ,  A61B6/503 ,  A61B6/504 ,  A61B6/5235 ,  A61B6/5288 ,  G06T7/254 ,  G06T2207/10121 ,  G06T2207/30048 ,  G06T2207/30101

Abstract: A method and an apparatus for motion visualization of a moving object in angiographic images are described. In a preferred embodiment of the method, first a mask image of the object of interest is acquired and a sequence of angiographic images of the object in different phases of motion of the object is acquired. Then, a first angiographic subtraction image and at least a second angiographic subtraction image are generated by subtracting the angiographic images from the mask image. Subsequently, a twice subtracted image is generated by subtracting the first angiographic subtraction image from the second angiographic subtraction image. In this way a double subtraction, i.e. a twice subtracted angiography is performed, to facilitate the assessment of the motion.

Abstract translation: 描述了用于血管造影图像中的移动物体的运动可视化的方法和装置。 在该方法的优选实施例中，首先获取感兴趣对象的掩模图像，并且获取对象在运动对象的不同阶段中的血管造影图像序列。 然后，通过从掩模图像中减去血管造影图像来生成第一血管造影减影图像和至少第二血管造影减影图像。 随后，通过从第二血管造影减影图像中减去第一血管造影减影图像来产生两倍的减影图像。 以这种方式，执行双减法，即进行两次减去的血管造影术，以便于评估运动。

公开(公告)号：US20100308229A1

公开(公告)日：2010-12-09

申请号：US12740366

申请日：2008-11-04

Applicant: Matthias Bertram ,  Jens Wiegert ,  John F. Vesel ,  David Sowards-Emmerd ,  Michael J. Petrilo

Inventor： Matthias Bertram ,  Jens Wiegert ,  John F. Vesel ,  David Sowards-Emmerd ,  Michael J. Petrilo

IPC: G01T1/166 ,  G21K1/10 ,  A61B6/00

CPC classification number: A61B6/032 ,  A61B6/037 ,  A61B6/4035 ,  G21K1/10

Abstract: When generating a 3D image of a subject or patient, a cone beam X-ray source (20a, 20b) is mounted to a rotatable gantry (14) opposite an offset flat panel X-ray detector (22a, 22b). A wedge-shaped attenuation filter (24a, 24b) of suitable material (e.g., aluminum or the like) is adjustably positioned in the cone beam to selectively attenuate the beam as a function of the shape, size, and density of a volume of interest (18) through which X-rays pass in order to maintain X-ray intensity or gain at a relatively constant level within a range of acceptable levels.

Abstract translation: 当产生被摄体或患者的3D图像时，锥形束X射线源（20a，20b）安装到与偏移平板X射线检测器（22a，22b）相对的可旋转机架（14）。 适当材料（例如铝等）的楔形衰减滤波器（24a，24b）可调节地定位在锥形束中，以根据感兴趣体积的形状，尺寸和密度来选择性地衰减光束 （18），以便在可接受水平的范围内使X射线强度或增益保持在相对恒定的水平。

公开(公告)号：US20100189376A1

公开(公告)日：2010-07-29

申请号：US12692786

申请日：2010-01-25

Applicant: Matthias BERTRAM ,  Jens WIEGERT ,  Steffen Gunther WIESNER

Inventor： Matthias BERTRAM ,  Jens WIEGERT ,  Steffen Gunther WIESNER

IPC: G06K9/40

CPC classification number: A61B6/032 ,  A61B6/4441 ,  A61B6/482 ,  G06T5/003 ,  G06T5/20 ,  G06T2207/10081

Abstract: The present invention relates to a detection values correction apparatus for correcting detection values of a projection image of a multi-energy imaging system. A scatter contribution providing unit provides scatter contributions for different intensities, different energies and different locations on the detection surface of the detection values. A scatter contributions combining unit combines scatter contributions for correcting a detection value, wherein the combined scatter contributions represent the contribution of the scatter, which is caused by radiation of the other detection values of the projection image, to the detection value to be corrected and wherein the scatter contributions are combined under consideration of the intensity, energy and location on the detection surface of the other detection values. A correction unit scatter corrects the detection value of the projection image by using the combined scatter contributions.

Abstract translation: 本发明涉及一种用于校正多能量成像系统的投影图像的检测值的检测值校正装置。 散射贡献提供单元为检测值的检测表面上的不同强度，不同能量和不同位置提供散射贡献。 散射贡献组合单元组合用于校正检测值的散射贡献，其中组合散射贡献表示由投影图像的其他检测值的辐射引起的散射对待校正的检测值的贡献，并且其中 在考虑其他检测值的检测表面上的强度，能量和位置的情况下组合散射贡献。 校正单位散射通过使用组合散射贡献校正投影图像的检测值。

公开(公告)号：US20080205723A1

公开(公告)日：2008-08-28

申请号：US12090359

申请日：2006-10-06

Applicant: Joerg Bredno ,  Georg Rose ,  Juergen Weese ,  Alexandra Groth ,  Sabine Mollus ,  Matthias Bertram ,  Jens Wiegert ,  Christoph Neukirchen

Inventor： Joerg Bredno ,  Georg Rose ,  Juergen Weese ,  Alexandra Groth ,  Sabine Mollus ,  Matthias Bertram ,  Jens Wiegert ,  Christoph Neukirchen

IPC: A61B6/00

CPC classification number: A61B6/032 ,  A61B6/481 ,  A61B6/488 ,  A61B6/507 ,  A61B6/542

Abstract: Adaptively controlling an imaging system (200, 205) includes constructing model feature characteristics (105) of a process over time, determining parameters and commands (110) for controlling the imaging system for each state of the process, performing data acquisition (120) for the process, extracting current features (130) of the process from the acquired data, matching (135) the current features (130) with the model feature characteristics (105) to determine a state of the process (140), and controlling the data acquisition based on the state of the process to produce optimized data.

Abstract translation: 自适应地控制成像系统（200,205）包括构建处理过程的模型特征特征（105），确定参数和命令（110），以控制成像系统对于每个处理状态，执行数据采集（120） 该过程从所获取的数据提取过程的当前特征（130），将当前特征（130）与模型特征特征（105）匹配（135）以确定过程（140）的状态，以及控制数据 根据进程的状态获取生成优化数据。

公开(公告)号：US09025840B2

公开(公告)日：2015-05-05

申请号：US13582124

申请日：2011-03-04

Applicant: Irina Waechter-Stehle ,  Alexandra Groth ,  Ronaldus Petrus Johannes Hermans ,  Matthias Bertram

Inventor： Irina Waechter-Stehle ,  Alexandra Groth ,  Ronaldus Petrus Johannes Hermans ,  Matthias Bertram

IPC: G06K9/00 ,  G06T7/20 ,  H05G1/64

CPC classification number: G06T7/2053 ,  A61B6/4441 ,  A61B6/4464 ,  A61B6/503 ,  A61B6/504 ,  A61B6/5235 ,  A61B6/5288 ,  G06T7/254 ,  G06T2207/10121 ,  G06T2207/30048 ,  G06T2207/30101

Abstract: A method and an apparatus for motion visualization of a moving object in angiographic images are described. In a preferred embodiment of the method, first a mask image of the object of interest is acquired and a sequence of angiographic images of the object in different phases of motion of the object is acquired. Then, a first angiographic subtraction image and at least a second angiographic subtraction image are generated by subtracting the angiographic images from the mask image. Subsequently, a twice subtracted image is generated by subtracting the first angiographic subtraction image from the second angiographic subtraction image. In this way a double subtraction, i.e. a twice subtracted angiography is performed, to facilitate the assessment of the motion.

Abstract translation: 描述了用于血管造影图像中的移动物体的运动可视化的方法和装置。 在该方法的优选实施例中，首先获取感兴趣对象的掩模图像，并且获取对象在运动对象的不同阶段中的血管造影图像序列。 然后，通过从掩模图像中减去血管造影图像来生成第一血管造影减影图像和至少第二血管造影减影图像。 随后，通过从第二血管造影减影图像中减去第一血管造影减影图像来产生两倍的减影图像。 以这种方式，执行双减法，即进行两次减去的血管造影术，以便于评估运动。

公开(公告)号：US08379791B2

公开(公告)日：2013-02-19

申请号：US13120660

申请日：2009-10-05

Applicant: Peter Forthmann ,  Thomas Koehler ,  Udo Van Stevendaal ,  Matthias Bertram ,  Steffen Wiesner ,  Colas Schretter

Inventor： Peter Forthmann ,  Thomas Koehler ,  Udo Van Stevendaal ,  Matthias Bertram ,  Steffen Wiesner ,  Colas Schretter

IPC: A61B6/00

CPC classification number: A61B6/032 ,  A61B5/107 ,  A61B6/027

Abstract: A method and apparatus are provided to improve CT image acquisition using a displaced acquisition geometry. A CT apparatus may be used having a source (102) and a detector (104) transversely displaced from a center (114) of a field of view (118) during acquisition of the projection data. The amount of transverse displacement may be determined based on the size of the object (108). The source and the detector may be adjusted to vary the size of the transverse field of view. The first data set acquired by the detector may be reconstructed and used to simulate missing projection data that could not be acquired by the detector at each projection angle. The measured projection data and the simulated projection data may be used to obtain a second data set. The second data set may be compared to the first data set to produce a corrected data set.

Abstract translation: 提供了一种方法和装置，用于改善使用位移采集几何形状的CT图像采集。 可以使用CT装置，在获取投影数据期间具有从视场（118）的中心（114）横向移位的源（102）和检测器（104）。 可以基于物体（108）的尺寸来确定横向位移量。 源和检测器可以被调节以改变横向视场的大小。 由检测器获取的第一数据集可以被重构并用于模拟在每个投影角度不能由检测器获取的丢失的投影数据。 所测量的投影数据和模拟投影数据可用于获得第二数据集。 可以将第二数据集与第一数据集进行比较以产生校正数据集。