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公开(公告)号：US08908939B2
公开(公告)日：2014-12-09
申请号：US13062227
申请日：2009-09-10
申请人： Joerg Bredno , Max Wintermark
发明人： Joerg Bredno , Max Wintermark
CPC分类号： A61B6/504 , A61B6/032 , A61B6/481 , A61B6/507 , G06F19/00 , G06F19/321 , G16H40/63 , G16H50/50
摘要： A system includes a perfusion information determiner (124) that determines perfusion information based on a combination of pre-perfusion scan image data and perfusion scan image data.
摘要翻译： 一种系统包括基于灌注前扫描图像数据和灌注扫描图像数据组合来确定灌注信息的灌注信息确定器（124）。
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公开(公告)号：US20130243298A1
公开(公告)日：2013-09-19
申请号：US13989152
申请日：2011-11-22
IPC分类号： G06T5/00
CPC分类号： G06T5/00 , A61B6/5258 , G06T5/50 , G06T11/008 , G06T2207/10072
摘要： When correcting for artifacts on an attenuation map caused by an artifact source in a computed tomography image, nuclear images are reconstructed two or more times, each time using a different correction technique or uncorrected attenuation data. Corresponding voxels in the reconstructed images are compared to identify local areas that change, i.e., are fragile and therefore low-confidence, and areas that do not vary or exhibit little variance among the plurality of reconstructed images and are thus accorded a higher confidence. The reconstructed nuclear image is overlaid with color encoding indicative of the amount of confidence accorded to each voxel value obtained by attenuation-corrected tomographic reconstruction.
摘要翻译： 当在计算机断层摄影图像中由伪像源引起的衰减图上的伪像进行校正时，每次使用不同的校正技术或未校正的衰减数据重建两次或更多次的核图像。 将重构图像中的相应体素进行比较，以识别改变的局部区域，即易碎且因此低置信度，以及在多个重建图像之间不变化或显示很小变化的区域，并因此赋予更高的置信度。 重建的核图像用表示通过衰减校正的断层摄影重建获得的每个体素值的置信度的颜色编码来叠加。
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公开(公告)号：US20100074504A1
公开(公告)日：2010-03-25
申请号：US12532459
申请日：2008-03-14
申请人： Antonius J.C. Bruijns , Ronaldus P.J. Hermans , Peter M.J. Rongen , Jarl J.P. Blijd , Herman Stegehuis , Joerg Bredno
发明人： Antonius J.C. Bruijns , Ronaldus P.J. Hermans , Peter M.J. Rongen , Jarl J.P. Blijd , Herman Stegehuis , Joerg Bredno
摘要： A method for acquiring fusion images of a periodically moving body organ and an apparatus adapted to implement such method is described. In a preferred embodiment of the method, X-rays are irradiated to the body organ and a multiplicity of mask images is acquired by X-ray detection at a high image acquisition rate of at least 60 frames per second. Then, contrast medium is injected into vessels of the body organ and subsequently at least one contrast image of the body organ with the contrast medium included in the vessels is acquired by X-ray detection. A matching image from the multiplicity of mask images is determined which has been acquired at substantially the same stage of the movement of the body organ as the contrast image. By calculating the difference between the matching mask image and the at least one contrast image a subtraction image of the body organ can be obtained and displayed. Using different image acquisition rates during mask image acquisition and contrast image acquisition high quality subtraction images can be achieved while at the same time reducing the overall X-ray exposure dose.
摘要翻译： 描述了一种用于获取定期移动的身体器官的融合图像的方法和适于实现这种方法的装置。 在该方法的优选实施例中，将X射线照射到身体器官，并且通过以至少60帧/秒的高图像采集率的X射线检测获取多个掩模图像。 然后，将造影剂注射到身体器官的血管中，随后通过X射线检测获得体内器官与包含在血管中的造影剂的至少一个对比图像。 确定来自多个掩模图像的匹配图像，其在与对比图像的身体器官的移动的基本相同的阶段已被获取。 通过计算匹配掩模图像和至少一个对比图像之间的差异，可以获得并显示身体器官的减影图像。 在掩模图像采集和对比度图像采集期间使用不同的图像采集率可以实现高质量的减影图像，同时减少整个X射线曝光剂量。
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公开(公告)号：US20090116715A1
公开(公告)日：2009-05-07
申请号：US12301639
申请日：2007-05-14
申请人： Joerg Bredno , Juergen Weese , Alexandra Groth
发明人： Joerg Bredno , Juergen Weese , Alexandra Groth
摘要： Diagnostic angiograms only provide the projected lumen of a coronary, which is only an indirect measure of blood flow and pressure decline. According to an exemplary embodiment of the present invention, a motion compensated determination of a flow dynamics and a pressure decline for stenosis grading is provided, in which the motion compensation is performed on the basis of a tracking of a first position of a first marker and a second position of a second marker in the projection data set. This may provide for a robust and precise flow dynamics and pressure decline determination.
摘要翻译： 诊断性血管造影仅提供冠状动脉的预计管腔，这仅是血流量和压力下降的间接测量值。 根据本发明的示例性实施例，提供了针对狭窄分级的流动动力学和压力下降的运动补偿确定，其中基于第一标记的第一位置的跟踪和 在投影数据集中的第二标记的第二位置。 这可以提供鲁棒和精确的流动动力学和压力衰减测定。
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公开(公告)号：US20080294038A1
公开(公告)日：2008-11-27
申请号：US12096436
申请日：2006-11-15
申请人： Juergen Weese , Alexandra Groth , Joerg Bredno , Tom Bruijns , Peter Rongen , Roel Hermans , Heidrun Steinhauser
发明人： Juergen Weese , Alexandra Groth , Joerg Bredno , Tom Bruijns , Peter Rongen , Roel Hermans , Heidrun Steinhauser
摘要： A system (900), method (100, 200) and apparatus (600, 700, 800) are provided for analyzing a blood flow in a vascular system from a dynamic diagnostic observation sequence (101) to determine blood flow parameters (112) for further determination of filters, replay speed and finally visualization of the replayed original and filtered sequences. A first embodiment (100) extracts features of the observation and uses these features to select an appropriate model from a database of pre-determined models of vascular system of interest which have associated parameters. These parameters are varied to create an instance of the model that best matches the original observation. A second embodiment (200) visualizes a replay of the original observation (101) and the observation (101′) predicted by the model to highlight differences therebetween. A third embodiment (800) provides filtering and control of the replay speed.
摘要翻译： 提供了一种系统（900），方法（100,200）和装置（600,700,800），用于从动态诊断观察序列（101）分析血管系统中的血流，以确定血流参数（112） 进一步确定滤镜，重放速度以及最终可重播的原始和过滤序列。 第一实施例（100）提取观察的特征并且使用这些特征从具有相关参数的感兴趣的血管系统的预定模型的数据库中选择适当的模型。 改变这些参数以创建与原始观察结果最匹配的模型实例。 第二实施例（200）可视化通过模型预测的原始观察（101）和观察（101'）的重放以突出其间的差异。 第三实施例（800）提供重放速度的过滤和控制。
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6.发明申请公开(公告)号：US20080192887A1
公开(公告)日：2008-08-14
申请号：US11815113
申请日：2006-01-31
申请人： Juergen Weese , Alexandra Groth , Joerg Bredno
发明人： Juergen Weese , Alexandra Groth , Joerg Bredno
CPC分类号： G06T11/003 , A61B6/481 , A61B6/504 , G06T7/0012 , G06T2207/10112 , G06T2207/10116 , G06T2207/30104 , G06T2211/404
摘要： The invention relates to a method and a system for the simultaneous reconstruction of the three-dimensional vessel geometry and the flow characteristics in a vessel system. According to one realization of the method, vessel segments (41) of a parametric models are fitted to differently oriented X-ray projections (Pl, Pk, PN) of the vessel system that are generated during the passage of a bolus of contrast agent, wherein the fitting takes the imaged contrast agent dynamics and physiological a priori knowledge into account. In an alternative embodiment, the vessel geometry is reconstructed progressively along each vessel, wherein a new segment of a vessel is added based on the continuity of the vessel direction, vessel radius and reconstructed contrast agent dynamics.
摘要翻译： 本发明涉及用于同时重建血管系统中三维血管几何形状和流动特征的方法和系统。 根据该方法的一个实现，参数模型的血管段（41）适合于不同取向的X射线投影（P ，P < 在造影剂团中通过期间产生的血管系统，其中拟合物考虑成像的造影剂动力学和生理学先验知识。 在替代实施例中，血管几何沿着每个血管逐渐重建，其中基于血管方向，血管半径和重建的造影剂动力学的连续性，添加血管的新的部分。
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公开(公告)号：US10111726B2
公开(公告)日：2018-10-30
申请号：US12597361
申请日：2008-04-23
申请人： Juergen Weese , Alexandra Groth , Joerg Bredno
发明人： Juergen Weese , Alexandra Groth , Joerg Bredno
摘要： The invention relates to a system (100) for computing a risk, the risk relating to injuring an anatomical structure by a medical device during a medical procedure, the system comprising: a structure unit (110) for obtaining a position of the anatomical structure; a device unit (120) for obtaining a position of the medical device; and a risk unit (130) for computing the risk relating to injuring the anatomical structure, based on the position of the medical device and the position of the anatomical structure. The system (100) may be used for planning a path of a medical device, which path minimizes said risk, or for monitoring said risk during the medical procedure.
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公开(公告)号：US09466133B2
公开(公告)日：2016-10-11
申请号：US14124289
申请日：2012-05-23
CPC分类号： G06T11/005 , A61B6/032 , A61B6/037 , A61B6/5205 , A61B6/5217 , A61B6/5235 , G06T11/008
摘要： A hybrid imaging system including a first imaging system configured to acquire low resolution anatomical data of a first field of view of an anatomical structure. A second imaging system is configured to acquire functional data of the first field of view of the anatomical structure. A reconstruction processor is configured to reconstruct the functional data based on attenuation data into an attenuation corrected image. In response to the attenuation corrected image showing regions of interest, with the first imaging system or another imaging system acquiring high resolution data of one or more portions of the first field of view containing the regions of interest. The reconstruction processor reconstructs the high resolution anatomical data into one or more high resolution images of the regions of interest.
摘要翻译： 一种混合成像系统，包括被配置为获取解剖结构的第一视野的低分辨率解剖学数据的第一成像系统。 第二成像系统被配置为获取解剖结构的第一视野的功能数据。 重构处理器被配置为基于衰减数据将功能数据重建成衰减校正图像。 响应于示出感兴趣区域的衰减校正图像，利用第一成像系统或另一成像系统获取包含感兴趣区域的第一视野的一个或多个部分的高分辨率数据。 重构处理器将高分辨率解剖数据重建成感兴趣区域的一个或多个高分辨率图像。
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公开(公告)号：US09299171B2
公开(公告)日：2016-03-29
申请号：US14007755
申请日：2012-04-02
CPC分类号： G06T11/005 , A61B5/0035 , A61B6/032 , A61B6/037 , A61B6/06 , A61B6/4085 , A61B6/4291 , A61B6/4417 , A61B6/5205 , A61B6/582 , F04C2270/041
摘要： A method comprises: acquiring imaging data using a tomographic radiological imaging apparatus (10); updating a calibration (42, 52) based on current information about the imaging apparatus; calibrating the imaging data using the up-to-date calibration; and reconstructing the calibrated imaging data to generate an image. The updating may be based on a current state of an idle or parked imaging modality that is not used in acquiring the imaging data, or on a measurement acquired together with the imaging data, or on the imaging data itself. For cone-beam computed tomography (CBCT) imaging data, the updating may comprise determining an intensity scale based upon intensity of at least one air pixel measured during the acquiring of the CBCT imaging data and updating an air scan template (60) by the intensity scale.
摘要翻译： 一种方法包括：使用断层摄影放射成像装置（10）获取成像数据; 基于关于成像设备的当前信息来更新校准（42,42）; 使用最新校准来校准成像数据; 并重构校准的成像数据以产生图像。 该更新可以基于在获取成像数据时不使用的空闲或停放的成像模式的当前状态，或者与成像数据一起获取的测量值，或者基于成像数据本身。 对于锥束计算机断层摄影（CBCT）成像数据，更新可以包括基于在获取CBCT成像数据期间测量的至少一个空气像素的强度来确定强度标度，并且将空气扫描模板（60）更新强度 规模。
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公开(公告)号：US09153012B2
公开(公告)日：2015-10-06
申请号：US13989152
申请日：2011-11-22
CPC分类号： G06T5/00 , A61B6/5258 , G06T5/50 , G06T11/008 , G06T2207/10072
摘要： When correcting for artifacts on an attenuation map caused by an artifact source in a computed tomography image, nuclear images are reconstructed two or more times, each time using a different correction technique or uncorrected attenuation data. Corresponding voxels in the reconstructed images are compared to identify local areas that change, i.e., are fragile and therefore low-confidence, and areas that do not vary or exhibit little variance among the plurality of reconstructed images and are thus accorded a higher confidence. The reconstructed nuclear image is overlaid with color encoding indicative of the amount of confidence accorded to each voxel value obtained by attenuation-corrected tomographic reconstruction.
摘要翻译： 当在计算机断层摄影图像中由伪像源引起的衰减图上的伪像进行校正时，每次使用不同的校正技术或未校正的衰减数据重建两次或更多次的核图像。 将重构图像中的相应体素进行比较，以识别改变的局部区域，即易碎且因此低置信度，以及在多个重建图像之间不变化或显示很小变化的区域，并因此赋予更高的置信度。 重建的核图像用表示通过衰减校正的断层摄影重建获得的每个体素值的置信度的颜色编码来叠加。
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