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公开(公告)号:US20170010212A1
公开(公告)日:2017-01-12
申请号:US15113128
申请日:2015-02-12
发明人: Klaus GERWERT , Jens WILTFANG , Julian OLLESCH , Andreas NABER , Jonas SCHARTNER , Carsten KÖTTING
IPC分类号: G01N21/3577 , G01N21/64 , G01N33/68 , G01N21/552
CPC分类号: G01N21/3577 , G01N21/05 , G01N21/552 , G01N21/6428 , G01N21/6458 , G01N33/6896 , G01N2021/6421 , G01N2800/2821 , G01N2800/2835
摘要: Provided herein is a biosensor for conformation and secondary structure analysis, notably for the direct non-invasive qualitative secondary structure analysis of a single selected protein within a complex mixture, as e.g. a body fluid, by vibrational spectroscopic methods. For the analysis it is not required that the selected substance be isolated, concentrated, or pretreated by a special preparative procedure.
摘要翻译: 本文提供了用于构象和二级结构分析的生物传感器,特别是用于复杂混合物内单个选定蛋白质的直接非侵入性定性二级结构分析。 体液,通过振动光谱法。 对于分析,不要求所选物质通过特殊的制备方法进行分离,浓缩或预处理。