公开(公告)号：US12105019B2

公开(公告)日：2024-10-01

申请号：US17637617

申请日：2020-08-31

申请人： FUJIKIN INCORPORATED

发明人： Masaaki Nagase ,  Masahiko Takimoto ,  Kazuteru Tanaka ,  Kouji Nishino ,  Nobukazu Ikeda

IPC分类号： G01N21/27 ,  G01N21/05 ,  G01N21/17

CPC分类号： G01N21/274 ,  G01N21/05 ,  G01N21/1717 ,  G01N2021/1731

摘要： The concentration measurement device 100 includes an electric unit 20 having a light source 22 and a photodetector 24, a fluid unit 10 having a measurement cell 1, a first light-transmission member 11 for transmitting light from the light source to the measurement cell, a second light transmission member 12 for transmitting light from the measurement cell to the photodetector, a lens 3A provided in the fluid unit, the lens 3A being arranged such that light from the first light transmission member is to be incident on the first position and light is to be emitted from the second position to the second light transmission member, a pressure sensor 5 for measuring pressure of fluid flowing through the measurement cell, and an arithmetic circuit 28 for detecting concentration of the fluid flowing through the measurement cell, the arithmetic circuit being configured to calculate the fluid concentration based on the output of the photodetector and a correction factor related to the pressure output by the pressure sensor and the concentration of fluid in order to reduce the measurement error due to the refractive index of the fluid.

公开(公告)号：US20240319074A1

公开(公告)日：2024-09-26

申请号：US18615783

申请日：2024-03-25

申请人： Endress+Hauser Conducta GmbH+Co. KG

发明人： Alejandro Vaca Torres ,  Hans Meyer ,  Andreas Müller

IPC分类号： G01N21/05 ,  G01N21/03

CPC分类号： G01N21/05 ,  G01N21/0303 ,  G01N2021/0389

摘要： A device for measuring a measured variable of a medium includes: a measuring cell, through which the medium can flow, in the inner chamber of which a channel opens on an inlet side and on an outlet side; a first duct opening into the inner chamber; a first component in the first duct such that an end portion of the first component projects into the inner chamber; and a first molded part, which surrounds on the end portion of the first component and a hollow chamber adjacent to the first component in the inner chamber, and includes, for each channel, a recess which connects the hollow chamber to the corresponding channel and is configured as a cross-sectional converter.

公开(公告)号：US12087797B2

公开(公告)日：2024-09-10

申请号：US18175836

申请日：2023-02-28

申请人： Illumina, Inc.

发明人： Xiuyu Cai ,  Ali Agah ,  Tracy H. Fung ,  Dietrich Dehlinger

IPC分类号： H01L27/146 ,  G01J1/02 ,  G01J1/44 ,  G01N21/05 ,  G01N21/64

CPC分类号： H01L27/14636 ,  G01J1/0209 ,  G01J1/0214 ,  G01J1/44 ,  G01N21/6454 ,  H01L27/14601 ,  H01L27/14609 ,  H01L27/1462 ,  H01L27/14625 ,  H01L27/14629 ,  H01L27/14643 ,  G01N21/05 ,  G01N2201/0642 ,  H01L27/14623

摘要： An example image sensor structure includes an image layer. The image layer includes an array of light detectors disposed therein. A device stack is disposed over the image layer. An array of light guides is disposed in the device stack. Each light guide is associated with at least one light detector of the array of light detectors. A passivation stack is disposed over the device stack. The passivation stack includes a bottom surface in direct contact with a top surface of the light guides. An array of nanowells is disposed in a top layer of the passivation stack. Each nanowell is associated with a light guide of the array of light guides. A crosstalk blocking metal structure is disposed in the passivation stack. The crosstalk blocking metal structure reduces crosstalk within the passivation stack.

公开(公告)号：US12078594B2

公开(公告)日：2024-09-03

申请号：US17983383

申请日：2022-11-08

申请人： Wyatt Technology, LLC

发明人： Drew Amaral ,  Vincent Hsieh

IPC分类号： G01N21/51 ,  G01N21/05 ,  G01N21/53

CPC分类号： G01N21/51 ,  G01N21/05 ,  G01N21/53 ,  G01N2021/513

摘要： The present disclosure describes a flow cell, a read head, and a skid attachment for measuring real-time molecular weight for downstream process control. In an embodiment, the flow cell comprises a hollow cylindrical tube, an inlet flange connected to an inlet of the tube, and an outlet flange connected to an outlet of the tube. In an embodiment, the read head comprises at least one push rod, at least two line contacts, where the at least one push rod is configured to push an outer side wall of a flow cell against the at least two line contacts. In an embodiment, the skid attachment comprises a plurality of arms connected to an enclosure configured to house at least a multi-angle light scattering instrument comprising a read head.

公开(公告)号：US20240280443A1

公开(公告)日：2024-08-22

申请号：US18654218

申请日：2024-05-03

申请人： Precision Planting LLC

发明人： Todd Swanson ,  Dale Koch ,  Hayden Splechter ,  Timothy Schaefer

IPC分类号： G01N1/08 ,  A01C23/00 ,  B01D19/00 ,  B01D21/26 ,  B01D29/11 ,  B01F23/50 ,  B01F23/53 ,  B01F23/80 ,  B01F25/30 ,  B01F25/54 ,  B01F27/1125 ,  B01F27/808 ,  B01F27/906 ,  B01F35/00 ,  B01F35/10 ,  B01F35/21 ,  B01F35/45 ,  B01F101/00 ,  B01F101/23 ,  B04B5/04 ,  F04B43/06 ,  G01G17/04 ,  G01N1/38 ,  G01N1/40 ,  G01N21/05 ,  G01N21/25 ,  G01N21/78 ,  G01N33/24 ,  G01N35/00 ,  G01N35/10 ,  G05B15/02

CPC分类号： G01N1/08 ,  A01C23/007 ,  B01D19/00 ,  B01D21/262 ,  B01D29/112 ,  B01F23/53 ,  B01F23/807 ,  B01F23/808 ,  B01F25/30 ,  B01F25/54 ,  B01F27/11253 ,  B01F27/808 ,  B01F27/906 ,  B01F35/1452 ,  B01F35/187 ,  B01F35/2117 ,  B01F35/453 ,  B04B5/0421 ,  F04B43/06 ,  G01G17/04 ,  G01N1/38 ,  G01N1/4055 ,  G01N1/4077 ,  G01N21/05 ,  G01N21/251 ,  G01N21/78 ,  G01N33/24 ,  G01N35/00584 ,  G01N35/1004 ,  G01N35/1095 ,  G05B15/02 ,  B01D2201/4092 ,  B01F23/581 ,  B01F2101/005 ,  B01F2101/23 ,  G01N2001/4061 ,  G01N2001/4083 ,  G01N2001/4088 ,  G01N33/245 ,  G01N2035/00188 ,  G01N2035/00475 ,  G01N2035/00495 ,  G01N2035/00514

摘要： An automated computer-controlled sampling system and related methods for collecting, processing, and analyzing agricultural samples for various chemical properties such as plant available nutrients. The sampling system allows multiple samples to be processed and analyzed for different analytes or chemical properties in a simultaneous concurrent or semi-concurrent manner. Advantageously, the system can process soil samples in the “as collected” condition without drying or grinding. The system generally includes a sample preparation sub-system which receives soil samples collected by a probe collection sub-system and produces a slurry (i.e. mixture of soil, vegetation, and/or manure and water), and a chemical analysis sub-system which processes the prepared slurry samples for quantifying multiple analytes and/or chemical properties of the sample. The sample preparation and chemical analysis sub-systems can be used to analyze soil, vegetation, and/or manure samples.

公开(公告)号：US12066375B2

公开(公告)日：2024-08-20

申请号：US16464759

申请日：2017-11-30

申请人： Cytiva Sweden AB

发明人： Hanno Ehring ,  Mats Lundkvist ,  David Carl Martin Bergman ,  Andreas Marcstrom

IPC分类号： G01N21/05 ,  G01N21/03 ,  G01N21/85

CPC分类号： G01N21/05 ,  G01N21/03 ,  G01N21/0303 ,  G01N21/85 ,  G01N2201/0668 ,  G01N2201/08

摘要： The invention relates to an optical flow cell comprising a housing forming an enclosed and elongated fluid channel arranged along a first axis, an inlet arranged to connect a first outer surface area of the housing to a first end of the fluid channel and an outlet arranged to connect a second outer surface area to a second end of the fluid channel, a first light guide and a second light guide concentrically arranged along a second axis and on opposite side walls of the fluid channel. The invention further relates to a corresponding method to produce an optical flow cell.

公开(公告)号：US20240269976A1

公开(公告)日：2024-08-15

申请号：US18615677

申请日：2024-03-25

申请人： CyVek, Inc.

发明人： Martin A. Putnam

IPC分类号： B32B37/10 ,  B01L3/00 ,  B32B37/00 ,  B32B37/02 ,  G01N21/03 ,  G01N21/05 ,  G01N21/64 ,  G01N33/543 ,  G01N35/00

CPC分类号： B32B37/1009 ,  B01L3/502707 ,  B32B37/0076 ,  B32B37/02 ,  G01N21/05 ,  G01N21/645 ,  G01N33/54366 ,  B01L2200/0689 ,  B01L2200/16 ,  B01L2300/087 ,  B01L2300/0887 ,  B01L2300/168 ,  B01L2400/0481 ,  B01L2400/0638 ,  B01L2400/086 ,  G01N2021/0346 ,  G01N2021/058 ,  G01N2035/00158 ,  Y10T29/494 ,  Y10T156/10

摘要： A method of making at least a portion of at least one microfluidic actuator having a flexible diaphragm portion and an opposite surface portion, the diaphragm and opposite surface each having opposed faces, at least one of the faces comprising surface-activated PDMS, and the opposed faces being arranged such that when the opposed faces contact each other, they form a fluidic seal, including performing repeated make-and-break-contact protocol on the contacting opposed faces until the tendency for permanent bonds to form between the contacting faces has been neutralized, thereby enabling the diaphragm portion to perform actuated movements to engage and disengage with the opposite surface portion, without the diaphragm sticking to the opposite surface portion.

公开(公告)号：US12053776B2

公开(公告)日：2024-08-06

申请号：US17854741

申请日：2022-06-30

申请人： ILLUMINA CAMBRIDGE LIMITED ,  ILLUMINA, INC.

发明人： Geraint Evans ,  Stanley S. Hong

IPC分类号： G01N21/05 ,  B01L3/00 ,  C12Q1/6869 ,  G01N21/64 ,  G02B27/42

CPC分类号： B01L3/502715 ,  G01N21/05 ,  G02B27/4227 ,  B01L2300/0829 ,  B01L2300/0861 ,  B01L2300/0896 ,  C12Q1/6869 ,  G01N2021/6482

摘要： For example, a flowcell includes: a nanowell layer having a first set of nanowells and a second set of nanowells to receive a sample; a first linear waveguide associated with the first set of nanowells, and a second linear waveguide associated with the second set of nanowells; and a first grating for the first linear waveguide, and a second grating for the second linear waveguide, the first and second gratings providing differential coupling of first light and second light.

公开(公告)号：US12038355B2

公开(公告)日：2024-07-16

申请号：US17144093

申请日：2021-01-07

申请人： Precision Planting LLC

发明人： Todd Swanson ,  Dale Koch ,  Reid Harman

IPC分类号： B01D21/26 ,  A01C23/00 ,  B01D19/00 ,  B01D29/11 ,  B01F23/53 ,  B01F23/80 ,  B01F25/30 ,  B01F25/54 ,  B01F27/1125 ,  B01F27/808 ,  B01F27/906 ,  B01F35/00 ,  B01F35/10 ,  B01F35/21 ,  B01F35/45 ,  B04B5/04 ,  F04B43/06 ,  G01G17/04 ,  G01N1/08 ,  G01N1/38 ,  G01N1/40 ,  G01N21/05 ,  G01N21/25 ,  G01N21/78 ,  G01N33/24 ,  G01N35/00 ,  G01N35/10 ,  G05B15/02 ,  B01F23/50 ,  B01F101/00 ,  B01F101/23

CPC分类号： G01N1/08 ,  A01C23/007 ,  B01D19/00 ,  B01D21/262 ,  B01D29/112 ,  B01F23/53 ,  B01F23/807 ,  B01F23/808 ,  B01F25/30 ,  B01F25/54 ,  B01F27/11253 ,  B01F27/808 ,  B01F27/906 ,  B01F35/1452 ,  B01F35/187 ,  B01F35/2117 ,  B01F35/453 ,  B04B5/0421 ,  F04B43/06 ,  G01G17/04 ,  G01N1/38 ,  G01N1/4055 ,  G01N1/4077 ,  G01N21/05 ,  G01N21/251 ,  G01N21/78 ,  G01N33/24 ,  G01N35/00584 ,  G01N35/1004 ,  G01N35/1095 ,  G05B15/02 ,  B01D2201/4092 ,  B01F23/581 ,  B01F2101/005 ,  B01F2101/23 ,  G01N2001/4061 ,  G01N2001/4083 ,  G01N2001/4088 ,  G01N2033/245 ,  G01N2035/00188 ,  G01N2035/00475 ,  G01N2035/00495 ,  G01N2035/00514

摘要： An automated computer-controlled sampling system and related methods for collecting, processing, and analyzing agricultural samples for various chemical properties such as plant available nutrients. The sampling system allows multiple samples to be processed and analyzed for different analytes or chemical properties in a simultaneous concurrent or semi-concurrent manner. Advantageously, the system can process soil samples in the “as collected” condition without drying or grinding. The system generally includes a sample preparation sub-system which receives soil samples collected by a probe collection sub-system and produces a slurry (i.e. mixture of soil, vegetation, and/or manure and water), and a chemical analysis sub-system which processes the prepared slurry samples for quantifying multiple analytes and/or chemical properties of the sample. The sample preparation and chemical analysis sub-systems can be used to analyze soil, vegetation, and/or manure samples.

公开(公告)号：US12031913B2

公开(公告)日：2024-07-09

申请号：US15036181

申请日：2013-12-25

申请人： Hitachi, Ltd.

发明人： Takashi Anazawa ,  Takahide Yokoi ,  Yuichi Uchiho

IPC分类号： G01N21/64 ,  B01L3/00 ,  G01N21/03 ,  G01N21/05 ,  G01N27/447

CPC分类号： G01N21/6454 ,  B01L3/5027 ,  G01N21/6402 ,  G01N21/6452 ,  G01N27/447 ,  G01N27/44721 ,  G01N27/44726 ,  G01N27/44791 ,  B01L2300/0858 ,  B01L2300/0864 ,  G01N2021/0346 ,  G01N21/05 ,  G01N2201/06113

摘要： Efficient simultaneous laser-irradiation-fluorescence detection is performed for a plurality of channels of a microchip and simple and highly sensitive parallel analysis of a plurality of samples is enabled. In a microchip 1 made of an optically transparent solid material m1 with a refractive index n1, a plurality of channels 2 filled with a material m2 with a refractive index n2 and a plurality of channels 3 filled with a material m3 with a refractive index n3 are alternately arranged in parallel on the same plane. Here, m1, m2 and m3 are selected such that a relation of n2