公开(公告)号：US11122814B2

公开(公告)日：2021-09-21

申请号：US16801250

申请日：2020-02-26

Applicant: Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali ,  Shaheen Majeed

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali ,  Shaheen Majeed

IPC: A61K35/742 ,  A23F3/30 ,  A23L2/52 ,  A23F5/36

Abstract: The present invention discloses beverage compositions comprising probiotic Bacillus coagulans and water soluble prebiotic fibers that have been subjected to treatments under extreme stress, temperature and pressure conditions like brewing or aeration wherein the spore viability is maintained post said treatments.

公开(公告)号：US10323227B2

公开(公告)日：2019-06-18

申请号：US15661218

申请日：2017-07-27

Applicant: Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali

IPC: C12N1/20 ,  C12P7/52 ,  C12P7/54 ,  C12P7/64 ,  A61K35/00 ,  A61K35/742

Abstract: Disclosed herein is a composition containing turmeric starch for use as a prebiotic plant fiber. Also disclosed is a method to increase the viable counts of Bacillus coagulans MTCC 5856 by co-culturing with turmeric starch and the production of short chain fatty acids (SCFA) by Bacillus coagulans MTCC 5856 using turmeric starch.

公开(公告)号：US20190060337A1

公开(公告)日：2019-02-28

申请号：US15971069

申请日：2018-05-04

Applicant: Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali

IPC: A61K31/7032 ,  A61P3/10

Abstract: Disclosed are the compositions for the effective regulation of carbohydrate breakdown and absorption. More specifically, the invention discloses compositions containing at least 10% w/w or above of 1-O-galloyl-β-D-glucose (β-glucogallin) and additionally comprising of about 10% w/w to greater than 60% w/w total mucic acid gallates for the effective regulation of carbohydrate breakdown and absorption by the inhibition of enzymes amylase, glucosidase and dipeptidyl peptidase.

公开(公告)号：US20180344628A1

公开(公告)日：2018-12-06

申请号：US15996791

申请日：2018-06-04

Applicant: Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali ,  Lakshmi Mundkur ,  Shaheen Majeed

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali ,  Lakshmi Mundkur ,  Shaheen Majeed

IPC: A61K8/99 ,  A61Q19/08

Abstract: Disclosed is the use of partially purified extracellular metabolite isolated from Bacillus coagulans MTCC 5856 to prevent skin aging. More specifically the invention discloses the anti-collagenase, anti-elastase, anti-glycation activity and enhancement of TGF-β, epidermal growth factor and hyaluronic acid expression in human dermal fibroblasts, of extracellular metabolites isolated from Bacillus coagulans MTCC 5856.

公开(公告)号：US20180338508A1

公开(公告)日：2018-11-29

申请号：US15806485

申请日：2017-11-08

Applicant: Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali ,  Shaheen Majeed

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali ,  Shaheen Majeed

IPC: A23F5/36 ,  A61K35/742 ,  A23L2/52 ,  A23F3/30

Abstract: The present invention discloses beverage compositions comprising probiotic Bacillus coagulans and water soluble prebiotic fibers that have been subjected to treatments under extreme stress, temperature and pressure conditions like brewing or aeration wherein the spore viability is maintained post said treatments.

公开(公告)号：US20160129054A1

公开(公告)日：2016-05-12

申请号：US14536701

申请日：2014-11-10

Applicant: Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Natarajan Sankaran ,  Priti Vaidyanathan ,  Sivakumar Arumugam ,  Suresh Kumar Karri

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Natarajan Sankaran ,  Priti Vaidyanathan ,  Sivakumar Arumugam ,  Suresh Kumar Karri

IPC: A61K35/742

CPC classification number: A61K35/742 ,  A61K2035/115

Abstract: The present invention discloses a process for the therapeutic management of diarrhea predominant irritable bowel syndrome in humans comprising the oral administration of Bacillus coagulans SBC37-01, MTCC 5856 (containing not less than 2 billion spores) along with standard treatment of care in a specific manner.

Abstract translation: 本发明公开了一种用于治疗人体腹泻主要肠易激综合征的治疗方法，其包括口服施用凝结芽孢杆菌SBC37-01，MTCC5856（含有不少于20亿个孢子）以及以特定方式进行护理的标准治疗 。

公开(公告)号：US10806760B2

公开(公告)日：2020-10-20

申请号：US15995393

申请日：2018-06-01

Applicant: Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali ,  Shaheen Majeed

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali ,  Shaheen Majeed

IPC: A61K35/742 ,  A61P1/14 ,  C12N1/20 ,  C12R1/07

Abstract: Disclosed are the methods and compositions for the reduction of intestinal gas/flatulence. Specifically a method for reducing flatulence using a composition containing probiotic bacteria Bacillus coagulans MTCC 5856 is disclosed. More specifically, the invention discloses a method for inhibiting the growth of microorganisms that facilitate the production of intestinal gas, using a composition containing probiotic bacteria Bacillus coagulans MTCC 5856.

公开(公告)号：US10792295B2

公开(公告)日：2020-10-06

申请号：US16001096

申请日：2018-06-06

Applicant: Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali ,  Shaheen Majeed

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali ,  Shaheen Majeed

IPC: A61K31/7024 ,  A61P31/04 ,  A61K35/742

Abstract: Disclosed are compositions containing at least 10% w/w or above of 1-O-galloyl-β-D-glucose (β-glucogallin) which additionally comprising of about 10% w/w to greater than 60% w/w total mucic acid gallates including mucic acid 1,4-lactone 5-O-gallate, mucic acid 2-O-gallate, mucic acid 6-Methyl ester 2-O-gallate, mucic acid 1-Methyl ester 2-O-gallate and ellagic acid, and a probiotic bacteria Bacillus coagulans MTCC 5856, individually or in combination for inhibiting the growth and managing infections of Helicobacter pylori.

公开(公告)号：US20190328798A1

公开(公告)日：2019-10-31

申请号：US16396876

申请日：2019-04-29

Applicant: Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Furqan Ali ,  Sivakumar Arumugam ,  Shaheen Majeed ,  Lakshmi Mundkur ,  Anurag Pande

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Furqan Ali ,  Sivakumar Arumugam ,  Shaheen Majeed ,  Lakshmi Mundkur ,  Anurag Pande

IPC: A61K35/742 ,  C12N1/20

Abstract: The present invention discloses a composition comprising heat inactivated spores and/or comprising heat inactivated vegetative cells of probiotic bacteria Bacillus coagulans, and a process for preparing the same. The invention also discloses a method of modulating immune function in mammals by activating macrophages, using a composition comprising Bacillus coagulans in the form of live or heat inactivated spore and/or vegetative cells.

公开(公告)号：US10166261B2

公开(公告)日：2019-01-01

申请号：US15198158

申请日：2016-06-30

Applicant: Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali

IPC: A61K35/742 ,  A61K35/00

Abstract: The present invention discloses the use of probiotics for therapeutic management of major depressive disorder (MDD). Specifically, the invention discloses the method of therapeutically managing MDD in mammals with Irritable bowel syndrome using probiotic strain Bacillus coagulans MTCC 5856.